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Drug List Book

Deltasone (Prednisone)

Deltasone (Prednisone) PRED-ni-sone Classification: Corticosteroid IFU: Severe inflammation, immunosuppression Action: Decreases inflammation, mainly by stabilizing leukocyte lysosomal membranes; suppresses immune response; stimulates bone marrow; and influences protein, fat, and carbohydrate metabolism Dosage: 1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg, 50 mg Route: P.O. Adverse Reaction: euphoria, insomnia, vertigo, headache, seizures, heart failure, arrhythmias, pancreatitis, hypokalemia, muscle weakness Interactions: NSAIDS: Increased risk of GI distress and bleeding Page 55

Depakote ER (Divalproex Sodium) dye-val-PRO-ex Classification: Neurologic IFU: Seizure, bipolar, migraine Action: Unknown. Probably increases brain levels of gamma-aminobutyric acid, which transmits inhibitory nerve impulses in the CNS. Dosage: 250 mg/5 ml, 100-500 mg Route: P.O., I.V. Adverse Reaction: sedation, headache, dizziness, nausea, vomiting, indigestion, diarrhea, thrombocytopenia, pancreatitis Interactions: Aspirin: May cause valproic acid toxicity Page 56

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