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11 months ago

Drug List Book

Diflucan (Fluconazole)

Diflucan (Fluconazole) floo-KON-a-zole Classification: Antifungal IFU: Fungal Infection Action: Inhibits fungal cytochrome P-450 (responsible for fungal sterol synthesis) and weakens fungal cell walls Dosage: 50 mg, 100 mg, 150 mg, 200 mg Route: P.O., I.V. Adverse Reaction: headache, dizziness, nausea, leukopenia, thrombocytopenia, anaphylaxis Interactions: Cyclosporine: Possible increased plasma levels of cyclosporine. Monitor serum, cyclosporine, and phenytoin. Page 61

Dilantin (Phenytoin) FEN-i-toyn Classification: Antiepileptic IFU: Seizures Action: Unknown. A hydantoin derivative that probably stabilizes neuronal membranes and limits seizure activity by either increasing efflux or decreasing influx of sodium ions across cell membranes in the motor cortex during generation of nerve impulses. Dosage: 50 mg, 125 mg/5 ml Route: P.O., I.V., I.M. Adverse Reaction: decreased coordination, mental confusion, nervousness, slurred speech, trouble with breathing, speaking, or swallowing Interactions: Antihistamines: May increase phenytoin activity and toxicity. Monitor patient. Page 62

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