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Drug List Book

Diovan (Valsartan)

Diovan (Valsartan) val-SAR-tan Classification: ARB IFU: Hypertension Action: Blocks the binding of angiotensin II to receptor sites in vascular smooth muscle and the adrenal gland, which inhibits the pressor effects of the renin-angiotensin-aldosterone system. Dosage: 80 mg, 160 mg Route: P.O. Adverse Reaction: dizziness, headache, neutropenia, nausea, abdominal pain Interactions: Diuretics: Risk of excessive hypotension. Assess fluid status before starting concomitant therapy. Page 63

Diovan HCT (Valsartan/ Hydrochlorothiazide) HYE-droe-klor-oh-THYE-a-zide / val-SAR-tan Classification: ARB/diuretic IFU: Hypertension Action: Blocks the binding of angiotensin II to receptor sites in vascular smooth muscle and the adrenal gland to relax the blood vessels. Helps the kidneys eliminate fluid and sodium from the body. Dosage: 160/12.5 mg, 320/25 mg Route: P.O. Adverse Reaction: cold or flu-like symptoms, difficulty swallowing, sore throat, unusual tiredness or weakness Interactions: Quinapril: May increase risk of side effects such as low blood pressure, kidney function impairment, and hyperkalemia Page 64

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