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Drug List Book

Elavil (Amitriptyline)

Elavil (Amitriptyline) a-mee-TRIP-ti-leen Classification: TCA (Tricyclic antidepressants) IFU: Depression Action: Unknown. Increases amount of norepinephrine, serotonin, or both in the CNS by blocking their reuptake by the presynaptic neurons. Dosage: 50 mg, 100 mg, 150 mg, 300 mg, (P.O.); 20 mg, 30 mg, (I.M.) Route: P.O., I.M. Adverse Reaction: coma, seizures, MI, CVA, arrhythmias, heart block, hypotension, dry mouth, thrombocytopenia Interactions: Epinephrine, norepinephrine: Increased hypertensive effect. Use with caution. Page 68

Enablex (darifenacin) dar-e-FEN-e-sin Classification: Urinary antispasmodic IFU: Overactive bladder Action: Reduces leaking of urine, feelings of needing to urinate right away, and frequent trips to the bathroom Dosage: 7.5 mg, 15 mg Route: P.O. Adverse Reaction: bladder pain, bloody or cloudy urine, difficult, burning, or painful urination, frequent urge to urine, lower back or side pain Interactions: Ketoconazole: May significantly increase the blood levels of darifenacin. This can increase side effects such as nausea, dry mouth, abdominal pain, constipation, and heartburn. Page 69

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