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Review of Pharmacology - 9E (2015)

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Gastrointestinal Tract<br />

recent Questions asked by National Board<br />

1. Which <strong>of</strong> the following stool s<strong>of</strong>teners does not interfere<br />

with fat absorption?<br />

(a) Docussates<br />

(b) Phenolphthalein<br />

(c) Liquid paraffin<br />

(d) Castor oil<br />

2. All <strong>of</strong> the following are true about ondansetron except:<br />

(a) Drug <strong>of</strong> choice for chemotherapy induced vomiting<br />

(b) Dopamine antagonist<br />

(c) 5HT 3<br />

antagonist<br />

(d) Used to prevent relapse in alcohol dependence<br />

3. Which <strong>of</strong> the following is the most potent 5HT 3<br />

antagonist?<br />

(a) Ondansetron<br />

(b) Granisetron<br />

(c) Dolasetron<br />

(d) Palonosetron<br />

4. Which drug is given in delayed vomitting after chemotherapy:<br />

(a) Metoclopramide<br />

(b) Hyoscine<br />

(c) Domperiodone<br />

(d) Aprepitant<br />

5. Antiemetic used in vomiting induced by anticancer<br />

drugs is:<br />

(a) Ondansetron<br />

(b) Cisapride<br />

(c) Metoclopramide<br />

(d) Trifluopromazine<br />

6. Which is not an adverse effect <strong>of</strong> cimetidine?<br />

(a) Impotence<br />

(b) Gynaecomastia<br />

(c) Atrophic gastritis<br />

(d) Galactorrhea<br />

7. Which <strong>of</strong> the following is not used in Crohn’s disease?<br />

(a) Infliximab<br />

(b) Adalimumab<br />

(c) Ustekinumab<br />

(d) Natalizumab<br />

8. Drug used in cancer chemotherapy induced vomiting<br />

is?<br />

(a) Aprepitant<br />

(b) Dexamethasone<br />

(c) Ondansetron<br />

(d) All <strong>of</strong> the above<br />

9. Which laxative acts by opening <strong>of</strong> chloride channels?<br />

(a) Docusate<br />

(b) Anthraquinone<br />

(c) Lubiprostone<br />

(d) Bisacodyl<br />

10. Primary role <strong>of</strong> antacids in peptic ulcer is:<br />

(a) Pain relief<br />

(b) Ulcer healing<br />

(c) H Pylori eradication<br />

(d) All <strong>of</strong> the above<br />

11. Drug not used in the treatment <strong>of</strong> H.pylori is:<br />

(a) Cisapride<br />

(b) Clarithromycin<br />

(c) Metronidazole<br />

(d) Omeprazole<br />

12. Which one <strong>of</strong> the following drugs increases gastrointestinal<br />

motility?<br />

(a) Glycopyrrolate<br />

(b) Atropine<br />

(c) Neostigmine<br />

(d) Fentanyl<br />

13. All <strong>of</strong> the following are true for metoclopramide except:<br />

(a) Chemically related to procainamide<br />

(b) Speeds gastric emptying<br />

(c) Stimulates chemoreceptor trigger zone<br />

(d) Blocks D 2<br />

receptors<br />

14. Which <strong>of</strong> the following purgative increases the fecal bulk<br />

due to their water absorbing and retaining capacity:<br />

(a) Methyl cellulose<br />

(b) Lactulose<br />

(c) Liquid paraffin<br />

(d) Dioctyl sodium sulfosuccinate<br />

15. A vitamin that is reducing agent, a property that may<br />

explain its function is:<br />

(a) Nicotinamide<br />

(b) Thiamine<br />

(c) Vitamin B 12<br />

(d) Vitamin C<br />

16. Which <strong>of</strong> the following 5-HT receptors play an important<br />

role in causing emesis?<br />

(a) 5HT 1<br />

(b) 5HT 2A/2C<br />

(c) 5HT 3<br />

(d) 5HT 4<br />

17. A prokinetic drug which lacks D 2<br />

receptor antagonistic<br />

action is which one <strong>of</strong> the following:<br />

(a) Metoclopramide<br />

(b) Domperidone<br />

(c) Cisapride<br />

(d) Chlorpromazine<br />

18. All <strong>of</strong> the following antibiotics have been used in<br />

treatment <strong>of</strong> H.pylori infection, except:<br />

(a) Clarithromycin<br />

(b) Amoxicillin<br />

(c) Metronidazole<br />

(d) Cipr<strong>of</strong>loxacin<br />

General Gastrointestinal <strong>Pharmacology</strong> Tract<br />

501<br />

https://kat.cr/user/Blink99/

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