1 month ago


14th EFMC Short Course

14th EFMC Short Course on Medicinal Chemistry 39 April 22-25, 2018 Oegstgeest (near Leiden), The Netherlands Course Organiser Bart DE SPIEGELEER (Ghent University, Belgium) Local Organiser Henk TIMMERMAN (VU University Amsterdam, The Netherlands) Peptide Therapeutics: Inspiring Beacon of Hope for the Pharmaceutical Future EFMC YEARBOOK 2018 In 2009, EFMC launched a series of short courses aimed to favour cultural and scientific growth of the medicinal chemistry community and organised with affordable fees for participation. These intensive courses are intended for scientists working in the field, and the presentations are given by senior scientists from industry and academia. The number of participants will be limited to 35, to favour in depth discussion. Should the number of applications exceed the maximum, preference will be given to applicants from EFMC adhering countries and employees of EFMC corporate members. Upon special request to the organisers, only based on financial conditions and supported by an argued recommendation of the head of the department of the applicant, a limited number of applicants from academia (maximum 3) may be admitted at a reduced fee. Course outline Peptides are a gigantic class of bioactive compounds, offering an immense chemical diversity as well as the potential for finding and characterizing new targets and also for developing non-peptidic ‘analogues’. However, the development of peptides into clinically useful pharmaceuticals is full of challenges including their pharmacokinetic properties (short biological half-life, lack of oral bioavailability, difficulties to reach intracellular or intranuclear targets) as well as their conformational flexibility which may cause reduced affinity and selectivity. However, recent developments in discovery, manufacturing and formulation, as well as in preclinical and clinical development, has triggered a lasting resurrection of pharmaceutical interest in peptide therapeutics. This EFMC seminar will bring together enthusiastic, approachable experts, both from academia and industry, on selected hot aspects in the discovery and development of peptide therapeutics. Real life examples and interactive discussions will give the participants a unique opportunity to learn in a short time how the challenges in peptide therapeutics can be handled and overcome. More details Comments of EFMC Short Course participants “Course covered whole range of interesting topics from the expert in the field. The strong and intensive interaction between participants and speakers made it really special meeting.” “I felt like every topic was discussed.” “Having the whole meeting ‘under one roof’ is appreciated. The castle is a very nice and comfortable location to organise an event such as the Short Course.” “I really enjoyed being part of a small group. Interaction between speakers and participants was great.” “One of the strong points of this course is the possibility to have good interaction with the speakers and ask a lot of questions, this makes it a real interactive school.” On a scale 0-5, the participants rated the speakers for content and presentation to an average of 4.2

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