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AHT Life Magazine 2018

Leading science and care

Leading science and care for animals We treat thousands of animals every year and help thousands more through our research... Our research to help dogs includes a mixture of clinical, genetics, cancer and stem cell research, which cover a wide range of diseases and injuries. Here are some of the key research themes: Blinding eye conditions… such as glaucoma, cataracts, lens luxation and corneal disease and injury. Dogs Neurological problems… such as epilepsy, cerebellar ataxia and intervertebral disc degeneration. Cancer… there are over 200 different types of cancer that can affect dogs. Our research aims to help dogs fight the most common aggressive cancers, such as mast cell tumours and lymphoma. Our research to help cats is currently focusing on deafness, heart disease and eye cancer. Distinguishing cancer from a natural change in cats’ eye colour A change in eye colour can be due to old age or iridal melanoma. We are looking at the ‘genetic blueprints’ of this cancer to try and create a clinical test to help vets make a diagnosis. Cats Why are some cats born deaf? We’re trying to understand more about the prevalence of congenital deafness in some breeds and the genetics involved. Finding new ways to treat heart disease We are starting to use stem cell technology to grow beating heart cells in the lab to better study feline heart disease. 18 AHT Life

Find out more at www.aht.org.uk Equine Herpesvirus (EHV) A viral infection that can cause abortion and respiratory and neurological disease in adult horses. We are working towards a vaccine. Flu We’re keeping an eye on the active equine flu viruses affecting horses in the UK, to make sure vaccines stay effective. Go to www.equiflunet.org.uk for updates. PPID / Equine Cushing’s Cancer We’re looking at the most important unanswered questions (which still need researching) to help ensure vets and horse owners get the most relevant and practical advice. Strangles The AHT’s diagnostic tests prevent thousands of horses getting Strangles every year, all around the world. Now we’re developing better vaccines to finally stop this plague on our horses. Through our clinical research, the AHT is constantly updating and improving radiation treatments for equines, to get the best possible outcomes Horses Tendon Injuries Developing new, safe and effective ready-to-use cell therapies to regenerate injured tendon tissue. Fractures We’re using stem cells to make bone in the lab in order to better understand why some racehorses are predisposed to fracture, and to develop a pioneering DNA test for at-risk horses. Equine Grass Sickness Our research hopes to establish if vaccination can be used to prevent this horrible, often fatal disease. Over 95% of horses and ponies that get equine grass sickness do not survive. Laminitis We’re creating the first set of evidence-based guidelines to help horse owners protect their animals from laminitis, which causes long-term changes in the foot. Lameness Our clinical research aims to provide scientific evidence for the prevention, identification, diagnosis and treatment of lameness and poor performance in both sports and pleasure horses. For more info on our clinical research go to pg 35 and 37. We need £15 million a year to fund our vital work, which is why the support of people like you is so important. Find out more about ways to support us on page 41. AHT Life 19

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