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Join the CONFIRM Initiative<br />

The CONFIRM Initiative is aimed at generating evidence that minipigs are a relevant non-rodent<br />

species for the immunological safety evaluation of human pharmaceuticals by setting up, promoting<br />

and coordinating a COllaborative Network For Immunological safety Research in <strong>Minipigs</strong>, abbreviated<br />

into ‘CONFIRM’.<br />

The CONFIRM Initiative is intended to:<br />

• serve as a trigger for immunological safety research in Göttingen <strong>Minipigs</strong><br />

• assist and synergize fundamental, translational and regulatory investigative efforts relevant to immunological safety<br />

evaluation in Göttingen <strong>Minipigs</strong><br />

• spread current knowledge and new findings to the scientific and regulatory toxicology community<br />

The first major meeting of the CONFIRM Initiative was held at the Minipig Research Forum in Barcelona in May and included<br />

three presentations which can be read at https://minipigresearchforum.org/members-area/the-mrf-meeting-2018/. We call<br />

on you to actively participate in the Initiative. Learn more at https://minipigs.dk/knowledge-base/the-confirm-initiative/ and<br />

please fill in the application form online If you are interested in joining. You can also apply for membership of our LinkedIn<br />

Group at https://www.linkedin.com/groups/13544253<br />

<strong>52</strong> AUTUMN 2018<br />

NEWSLETTER<br />

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Towards 3Rs: Multiplex protein profiling<br />

from minipig, cyno, dog and rat samples,<br />

to get the most out of preclinical safety<br />

studies page 3<br />

Experience with mixed groups of intact<br />

female and castrated male Göttingen <strong>Minipigs</strong><br />

See<br />

where you<br />

can meet us<br />

in 2018<br />

page 28<br />

Minipig<br />

Research<br />

Forum 2018<br />

page 20<br />

for pharmacokinetic studies in drug discovery research<br />

– summary of behavioral observations and collected<br />

back-ground data page 6<br />

Anti-cancer drug development: Comparison of toxicity<br />

in Göttingen <strong>Minipigs</strong> and mouse page 10<br />

Body surface area measurement in Göttingen <strong>Minipigs</strong><br />

using a computed tomography scanner page 14<br />

The Göttingen Minipig for the study of buccal and sublingual<br />

products page 17<br />

Update from Oriental Yeast Co., Ltd., Japan page 24<br />

Update from WOOJUNGBIO, Korea page 25<br />

Update from Marshall BioResources North America page 26<br />

New scientific publications on the Göttingen Minipig page 27<br />

Join the CONFIRM Initiative page 28<br />

Clean pigs<br />

for clear results<br />

The next <strong>Newsletter</strong> delivered<br />

directly to your inbox<br />

Our scientific newsletter is published three times a year. We welcome new and former<br />

subscribe that we might have lost contact with during the recent GDPR process, and<br />

ask you to sign up at https://minipigs.dk/contact-us/sign-up-for-our-newsletter/.<br />

If you have suggestions for topics and/or author, for a comming issue of the <strong>Newsletter</strong>,<br />

please email the editor: Søs Pihl-Poulsen at spp@minipigs.dk.<br />

Meeting Calendar Autumn 2018<br />

Name Date Location<br />

EUROTOX 2 - 5 September Brussels, Belgium<br />

ESTP 11 - 14 September Copenhagen, Denmark<br />

GV-SOLAS + IGTP 12 - 14 September Munich, Germany<br />

SPS 30 September - 3 October Washington, Columbia, USA<br />

LAVA-ESLAV-ECLAM 15 - 16 October Barcelona, Spain<br />

STP-I 26 - 28 October Hyderabad, India<br />

ACT 4 - 7 November Palm Beach, Florida, USA<br />

AFLAS 28 November - 1 December Bangalore, India<br />

Europe and Asia<br />

<strong>Ellegaard</strong> Göttingen <strong>Minipigs</strong> A/S<br />

Sorø Landevej 302,<br />

DK-4261 Dalmose,<br />

Denmark<br />

Tel.: +45 5818 5818<br />

ellegaard@minipigs.dk<br />

North America<br />

Marshall BioResources<br />

North Rose, NY 14516, USA<br />

Tel.: +1 315 587 2295<br />

Fax: +1 315 587 2109<br />

infous@marshallbio.com<br />

Japan & Taiwan<br />

Oriental Yeast Co. Ltd.<br />

3-6-10, Azusawa, Itabashi-ku<br />

Tokyo, 174-8505, Japan<br />

Tel.: +81 3 3968 1192<br />

Fax: +81 3 3968 4863<br />

fbi@oyc.co.jp<br />

Korea<br />

WOOJUNGBIO<br />

B-3F, 145 Gwanggyo-ro,<br />

Yeongtong-gu, Suwon, Korea<br />

Tel.: +82 31 888 9369<br />

Fax: +82 31 888 9368<br />

wj@woojungbsc.co.kr<br />

www.minipigs.dk<br />

JANNERUP GRAFISK

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