18.02.2019 Views

Gene Variant Report issued

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Lifestyle Genomics Research Centre Ltd.<br />

Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM<br />

contact us<br />

SAMPLE PROCESSED BY:<br />

METHOD:<br />

DATA CHECKED FOR ACCURACY BY:<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />

sequencing<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

NOTES:<br />

genotype has no risk alleles<br />

genotype has one risk allele<br />

READ THIS FIRST JOIN US ON FACEBOOK BOOK AN APPOINTMENT<br />

genotype has two risk allels<br />

either allele can be a risk or be<br />

beneficial<br />

Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />

SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />

rs887829 rs887829 UGT1A1 Chemoprotection / Detox II TT CC<br />

rs3755319 rs3755319 UGT1A1 Chemoprotection / Detox II AA AC<br />

rs6742078 rs6742078 UGT1A1 G179250T Chemoprotection / Detox II TT GG<br />

rs4148323 rs4148323 UGT1A1 G211A Chemoprotection / Detox II AA GG<br />

rs1523127 rs1523127 PXR Chemoprotection / Detox II & III CC AA<br />

rs2062541 rs2062541 ABCC1 / MRP1 Chemoprotection / Detox III AA GG<br />

rs4148382 rs4148382 ABCC1 / MRP1 Chemoprotection / Detox III AA GG<br />

rs246240 rs246240 ABCC1 / MRP1 Chemoprotection / Detox III GG AG<br />

rs2273697 rs2273697 ABCC2 Chemoprotection / Detox III AA GG<br />

rs8187710 rs8187710 ABCC2 Chemoprotection / Detox III AA GG<br />

rs717620 rs717620 ABCC2 Chemoprotection / Detox III TT CC<br />

rs1405655 rs1405655 LXR Chemoprotection / Detox III TT TT<br />

rs17373080 rs17373080 LXR Chemoprotection / Detox III GG CC<br />

rs2695121 rs2695121 LXR Chemoprotection / Detox III TT CC<br />

rs3741049 rs3741049 ACAT1 G22670A Chemoprotection / Detox III / Bile Flow AA GG<br />

rs3733890 rs3733890 BHMT Chemoprotection / Detox III / Bile Flow AA GG<br />

rs7946 rs7946 PEMT Chemoprotection / Detox III / Bile Flow TT TT

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