C-Flex TM was here.
PEOPLE. PRODUCTS. PROGRAMS. ®
*Mark S. Aloia, PhD et al., “Treatment Adherence and Outcomes in Flexible vs Standard Continuous Positive Airway Pressure,” Chest /127/ 6 / June 2005; pp. 2085-2093.
Feel and see the C-Flex difference.
It’s not hard to discover that C-Flex is a more comfortable
treatment for sleep apnea — you can feel the difference
with a quick demonstration. The difference is the C-Flex
waveform: a better way to deliver sleep therapy that
takes the work out of exhalation. You may also see a
difference in your patients who use C-Flex. Patients
simply feel better, and with good reason.
A study published in the June 2005 issue of Chest *
showed that patients using a REMstar Pro with C-Flex
used their therapy an average of 1.7 hours longer per
night than patients on CPAP after three months, and the
difference in adherence widened over time.
And to help you bring that promise of better results and
more comfortable therapy to more of your patients, we’ve
developed a family of REMstar devices with C-Flex so
you can match each of your patients to a device that fits
The REMstar family gives you a choice of therapy modes,
reporting modes and humidification options to deliver a truly
tailored therapy solution to your patients. And now you have
even more choices to offer with the new REMstar Auto with
C-Flex and the REMstar Pro 2 with C-Flex.
How C-Flex works.
The difference that patients feel when using C-Flex comes, in large part, from Digital Auto-Trak ® . This patented algorithm precisely
identifies the transition between inhalation and exhalation – even in the presence of mask leak and other variables. Digital Auto-Trak
helps therapy feel more natural by matching therapy to the patient’s natural breathing pattern. And by matching the patient’s breathing
pattern, C-Flex can reduce pressure at the moment of expiration.
With three C-Flex levels, patients have the ability to select the level of pressure relief that’s right for them. The amount of pressure
relief will vary on a breath-by-breath basis depending on the patient’s expiratory flow and the C-Flex setting. The device returns to the
prescribed pressure at the end of exhalation to ensure proper therapy.
C-Flex setting = 1
C-Flex setting = 2
C-Flex setting = 3
The new REMstar Pro 2 with C-Flex, like all REMstar devices with C-Flex,
reduces therapy pressure right at the point that a patient begins to exhale.
The level of pressure relief will vary with every breath and can be increased
or decreased with one of three C-Flex settings to make therapy more
comfortable. And that can make long-term compliance easier to achieve.
REMstar ® Pro 2 with C-Flex
and REMstar Auto with C-Flex:
Two new ways for patients to
feel the difference.
To complete the family of REMstar devices with C-Flex,
we’ve added powerful new reporting features to the
REMstar Pro. Also, we’ve combined auto-titration with
C-Flex to introduce the REMstar Auto with C-Flex – the
most comfortable smart CPAP we’ve ever produced.
REMstar Pro 2 with C-Flex advances the ability of our
top-of-line sleep therapy system by adding the ability to
record apnea/hypopnea index, leak levels and snoring.
This gives you even more insight into a patient’s therapy
regimen – and makes it easier to identify any need to
The REMstar Auto with C-Flex features a “multi-level”
algorithm that measures instances of flow limitation to
make systematic, subtle changes in pressure and assesses
the impact of these changes on the patient’s breathing
patterns. It can also determine how much of a response is
necessary to eliminate events and position the patients with
a more appropriate pressure – as well as compensate for
elevated leak levels and variable breathing.
Combining C-Flex and auto-titration makes the REMstar
Auto with C-Flex a particularly attractive device in a
sleep lab setting – especially when used in conjunction
with our Analog Output Module and Clinical Remote.
Breathing pattern recognition ensures the right therapy.
As impressive as the Proactive Algorithm therapy is, it would be useless without the Breathing Pattern Recognition ability of the
REMstar Auto with C-Flex. Breathing Pattern Recognition analyzes the shape curve of a patient’s airflow signal based on four
parameters (roundness, flatness, peak and shape). It can then seek out instances of flow limitation and respond accordingly –
either by cycling through the Pcrit, Popt and Ptherapy modes or by triggering the REMstar Auto’s secondary analysis.
REMstar Auto with C-Flex Theory of Operation
Flow Limitation/Primary Analysis
This simple mail-in card helps
reduce home visits and eliminates
the need for patients to transport
their device to your facility.
The true database architecture
of the Encore Pro software
gives you the power to create
customized reports based on
your needs, including detailed
daily reports, compliance reports
and long-term therapy trends.
Encore ® Pro SmartCard ® Compatible
The secondary analysis determines the occurrence
of breathing problems like apnea, hypopnea, snoring,
variable breathing and elevated leak levels based on
their effects on the patient’s airflow signal. Once it
detects one of these events, the secondary analysis
immediately begins to ramp up the pressure level to
a point that eliminates or compensates for the event.
REMstar Auto with C-Flex and the new REMstar Pro 2 with C-Flex come complete with Respironics’
Encore Pro SmartCard technology built in. This powerful tool allows you to handle patient files, develop
patient reports and track overall treatment progress of patient populations. Encore Pro’s true database
architecture unleashes its ability to manipulate and manage patient data. You can even compare the
wellness trends of different patients to explore ways to improve overall care based on different criteria
such as insurance provider or sleep lab.
The SmartCard records the date, time, ramp usage and duration of each session. Additionally, both
machines allow the SmartCard to record leak, apnea/hypopnea index and snoring – data previously
only available from the REMstar Auto with C-Flex. It can even be programmed to update the patient’s
prescription – when the programmed SmartCard is inserted, the prescription settings are automatically
transferred into the device – so, no in-home visit is required.
The REMstar family of devices with C-Flex is your choice for designing
customized outcomes-based treatment plans for sleep apnea patients,
while helping you to meet your clinical and business goals. All systems
feature a sleek, updated design that includes backlit controls for the unit
and humidification system.
REMstar Plus with C-Flex
REMstar Plus with C-Flex offers optional integrated humidification,
lighted controls, an easy-to-read display and the revolutionary comfort
of C-Flex – all in a sleek design. This is the device that will redefine
the entry-level CPAP market.
REMstar Pro 2 with C-Flex
REMstar Pro 2 with C-Flex combines the amazing comfort of C-Flex and
optional integrated humidification with the power of Encore ®
Management Software. And now with the ability to record apnea/hypopnea
index, elevated leak levels and snoring, it’s the most versatile CPAP
we’ve ever offered.
REMstar Auto with C-Flex
The REMstar Auto with C-Flex is an ideal flow-based Smart CPAP for
use in the lab or home. Its Proactive Algorithm looks for and adjusts
to a patient’s needs based on optimal and critical pressure levels. And
the new Encore Pro software allows you to track events like snoring,
elevated leak levels and apnea/hypopnea. Add that to a host of other
great patient features, and it’s easy to see why REMstar Auto with
C-Flex is the smartest Smart CPAP we’ve ever made.
REMstar Heated Humidifier
Designed as an integrated addition to our REMstar family, this unique,
tubeless platform brings heated humidification to a new level. Its clear,
two-piece water chamber is easy to fill and is dishwasher safe. The
humidifier controls are on the CPAP unit, and the heated humidifier
plugs directly into the REMstar unit – so there is only one plug going
into the wall.
REMstar Integrated Pass-over Humidifier
This integrated pass-over humidifier’s revised design allows you to
choose unheated humidification without sacrificing the convenience
of the REMstar heated humidifier’s sleek, integrated design.
REMstar Plus with C-Flex
REMstar Pro 2 with C-Flex
REMstar Auto with C-Flex
REMstar Heated Humidifier
REMstar Plus with C-Flex REMstar Pro 2 with C-Flex REMstar Auto with C-Flex
PRESSURE RANGE 4 to 20 cm H2O 4 to 20 cm H2O 4 to 20 cm H2O RAMP TIME 0 to 45 min. (5-min. increments) 0 to 45 min. (5-min. increments) 0 to 45 min. (5-min. increments
– CPAP mode only)
STARTING RAMP PRESSURE 4 to CPAP; patient-adjustable 4 to CPAP; patient-adjustable 4 to CPAP; patient-adjustable
(CPAP mode only)
DIMENSIONS 9.45" (l) x 6.69" (w) x 4.72" (h) 9.45" (l) x 6.69" (w) x 4.72" (h) 9.45" (l) x 6.69" (w) x 4.72" (h)
24 cm (l) x 17 cm (w) x 12 cm (h) 24 cm (l) x 17 cm (w) x 12 cm (h) 24 cm (l) x 17 cm (w) x 12 cm (h)
WEIGHT < 4 lbs (1.8 kg) < 4 lbs (1.8 kg) < 4 lbs (1.8 kg)
FILTERS Pollen and optional ultra-fine Pollen and optional ultra-fine Pollen and optional ultra-fine
DEVICE SET-UP On-board keypad On-board keypad and SmartCard On-board keypad and SmartCard
DATA STORAGE CAPACITY Therapy meter 6 months @ 3 usage sessions/day, 6 months @ 3 usage sessions/day,
(minimum) 7-9 days in-depth data analysis 7-9 days in-depth data analysis
DATA STORAGE CONTENT Total hours Date/time, duration at pressure, Date/time, duration at pressure,
Usage sessions > 4 hours patient event histograms, short-term patient event histograms, short-term
detailed events, long-term trends, detailed events, long-term trends,
FOSQ tests FOSQ tests
COMPLIANCE METER Therapy hours Breathing detection Breathing detection
ALTITUDE COMPENSATION Low, medium or high Automatic Automatic
ELECTRICAL REQUIREMENTS 100 – 240 AC, 12 VDC 100 – 240 AC, 12 VDC 100 – 240 AC, 12 VDC
DC POWER Direct-connect cord Direct-connect cord Direct-connect cord
WARRANTY 2 years 2 years 2 years
MISCELLANEOUS Integrated heated humidification control, Integrated heated humidification Integrated heated humidification
lighted keys on pad, pressure calibration key, control, lighted keys on pad, control, lighted keys on pad,
automatic on/off, mask off alert automatic on/off, mask off alert automatic on/off, mask off alert
CPAP Systems (North America only) Part #
REMstar Pro 2 with C-Flex 1020923
REMstar Pro 2 with C-Flex Core Pkg. (Incl. Humidifier) 1020926
REMstar Plus with C-Flex 1009586
REMstar Plus with C-Flex Core Pkg. (Incl. Humidifier) 1009871
REMstar Auto with C-Flex 1017453
REMstar Auto with C-Flex Core Pkg. (Incl. Humidifier) 1017476
Encore Pro Software and SmartCard Part #
ENCORE PRO SOFTWARE 1009583
ENCORE SHIELDED COMMUNICATIONS CABLE (6 ft/1.83 m) 1000814
ENCORE 9 TO 25 PIN CABLE ADAPTER 532348
SMARTCARD READER STATION
(Incl. universal supply, 115 VAC cord and interface cable. 220V cord sold separately.) 1003543
PACK OF SMARTCARDS (10 cards) 1003304
FOSQ CLINICAL REPRINT (Sleep, 20(10): 835-843) 1000141
FOSQ QUESTIONNAIRE, ENGLISH
(Call Customer Service for other languages.) 1004550
CPAP Accessories Part #
POLLEN FILTERS (Reusable; 2 per pack) 1005964
ULTRA-FINE FILTERS (Disposable; 2 per pack) 1005945
FILTER CAP 1008479
CARRYING CASE 1005965
DC ADAPTER CORD 1001956
SHIELDED DC CORD SYSTEM
(Incl. shielded DC cord and battery adapter cable) 1001979
REUSABLE PATIENT TUBING (6 ft. (1.8 m), GRAY) 622038
Humidifiers Part #
REMstar HEATED HUMIDIFIER 1005792
REMstar HEATED HUMIDIFIER CHAMBER (Replacement) 1008619
REMstar INTEGRATED PASS-OVER HUMIDIFIER 1011785
Customer Service: 1-800-345-6443 or 724-387-4000
Respironics Europe: +33-1-55-60-19-80
Respironics Asia Pacific: +81-3-5280-9611
CAUTION: U.S. federal law restricts these devices to sale by or on the order of a physician.
Respironics, REMstar, Encore, SmartCard and Auto-Trak are trademarks and “People. Products.
Programs.” is a registered service mark of Respironics, Inc. and its affiliates. The C-Flex mark is
used under license. Covered by one or more patents. Other patents pending.
©2005 Respironics, Inc. and its affiliates. All rights reserved.
Hoech KW 06/29/05 MCI 4100278 PN 1024560