ultrasound diagnosis of fatal anomalies
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ABDOMEN
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smaller omphaloceles, vaginal delivery is
possible and here there is no indication for cesarean
delivery.
Procedure after birth: The omphalocele should
be covered immediately with a sterile plastic bag
to avoid fluid loss. A nasogastric tube should be
placed to remove stomach contents. Early surgical
intervention within the first week. The earlier
practice of smearing a sterile antiseptic solution
on the lesion and delaying surgical intervention
has ceased to be used except in rare
cases of an extremely large omphalocele.
Prognosis: This is determined by the presence of
associated anomalies and the extent of the lesion.
The overall survival lies between 30–70%.
In a small isolated case of omphalocele, the prognosis
is very good (mortality below 5%). The
mortality increases considerably ( 30%) if the
defect is large ( 5 cm in the second trimester)
and if the liver is prolapsed, even if no other
anomalies are present.
Information for the mother: Surgical correction
is very successful nowadays. If rare cases of large
lesions with liver protrusion, associated malformations
and chromosomal anomalies are excluded,
then the long-term survival of the infant
is very good, without significant long-term impairment.
References
Achiron R, Soriano D, Lipitz S, Mashiach S, Goldman B,
Seidman DS. Fetal midgut herniation into the umbilical
cord: improved definition of ventral abdominal
anomaly with the use of transvaginal sonography.
Ultrasound Obstet Gynecol 1995; 6: 256–60.
Bonilla-Musoles F, Machado LE, Bailao LA, Osborne NG,
Raga F. Abdominal wall defects: two- versus threedimensional
ultrasonographic diagnosis. J Ultrasound
Med 2001; 20: 379–89.
Curtis JA, Watson L. Sonographic diagnosis of omphalocele
in the first trimester of fetal gestation. J Ultrasound
Med 1988; 7: 97–100.
Hughes MD, Nyberg DA, Mack LA, Pretorius DH. Fetal
omphalocele: prenatal US detection of concurrent
anomalies and other predictors of outcome. Radiology
1989; 173: 371–6.
Kilby MD, Lander A, Usher SM. Exomphalos (omphalocele).
Prenat Diagn 1998; 18: 1283–8.
Nyberg DA, Fitzsimmons J, Mack LA, et al. Chromosomal
abnormalities in fetuses with omphalocele: significance
of omphalocele contents. J Ultrasound Med
1989; 8: 299–308.
Pagliano M, Mossetti M, Ragno P. Echographic diagnosis
of omphalocele in the first trimester of pregnancy. J
Clin Ultrasound 1990; 18: 658–60.
Salvesen KA. Fetal abdominal wall defects: easy to diagnose—and
then what? Ultrasound Obstet Gynecol
2001; 18: 301–4.
Skupski DW. Prenatal diagnosis of gastrointestinal
anomalies with ultrasound: what have we learned?
Ann NY Acad Sci 1998; 847: 53–8.
Towner D, Yang SP, Shaffer LG. Prenatal ultrasound findings
in a fetus with paternal uniparental disomy
14 q12-qter [review]. Ultrasound Obstet Gynecol
2001; 18: 268–71.
Tseng JJ, Chou MM, Ho ES. In utero sonographic diagnosis
of a communicating enteric duplication cyst in a
giant omphalocele. Prenat Diagn 2001; 21: 540–2.
van de Geijn EJ, van Vugt JM, Sollie JE, van Geijn HP. UItrasonographic
diagnosis and perinatal management
of fetal abdominal wall defects. Fetal Diagn
Ther 1991; 6: 2–10.
Wilson BR, Turner D, Langendoerfer S, Haverkamp AD.
Prenatal diagnosis and subsequent team approach to
the management of omphalocele. J Reprod Med
1980; 24: 134–6.
Wilson RD, McGillivray BC. Omphalocele: early prenatal
diagnosis by ultrasound [letter]. JCU J Clin Ultrasound
1984; 12: A4.
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