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ultrasound diagnosis of fatal anomalies

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DETERMINATION OF ZYGOSITY

Fig. 15.4 Quadruplets. Tetra-amniotic, tetrachorionic

quadruplets at 9 + 3 weeks.

Fig. 15.5 Triplets. Triamniotic, monochorionic triplets

at 8 + 3 weeks. There is a thin membrane (only

amnion, with no chorion) separating the amniotic

cavities.

Measurement of nuchal translucency at

13 weeks also allows risk evaluation of TTTS. In

early TTTS, fluid accumulation in the recipient

twin causes nuchal edema, and nuchal translucency

measurements are significantly higher

than in the donor twin. If there is no significant

difference in nuchal translucency measurements

between the two twins, then the risk of

developing TTTS is assumed to be low.

From 16 weeks onwards, regular ultrasound

assessment of fetal growth and amniotic fluid

volume is necessary. Early warning signs of TTTS

development can be detected in this way, and

various therapy options can then be considered.

It may even be necessary to hospitalize the

mother.

To improve the prognosis of TTTS, continuous

assessment during the whole of the pregnancy is

advisable. The complications foreseen can be

discussed with a pediatrician to ensure the best

clinical management for the twins in this very

precarious situation.

In summary, ultrasound examination in early

pregnancy is a simple and reliable method of detecting

zygosity and thus whether there is a

high-risk pregnancy—allowing for risk-adjusted

antenatal management of twin pregnancies.

Self-Help Organizations

Title: National Organization of Mothers of

Twins Clubs

Description: Opportunity for mothers of multiple

births share information, concerns, and

advice on dealing with their unique problems

and joys. Literature, quarterly newspaper,

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