Senior Design Expo 2022

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Biomedical Engineering NeuroNotice Golda Daphna, Luis Muncharaz Duran, Kalsoum Mbacke, Rhea Sablani, Elaine Tan Peripheral neuropathy (PN) is a common consequence of diabetes marked by damage to peripheral nerves. PN usually originates in the extremities (hands and feet,) and if left undiagnosed can lead to infections, amputation, and life-threatening illness. Current diagnostic procedures include electromyograms and nerve conduction studies. However, the high cost, inconvenience, and invasiveness associated with these procedures may deter at-risk patients from regularly getting checked for PN. We propose NeuroNotice, an affordable, at-home, and user-friendly solution that allows patients to monitor symptoms of PN. NeuroNotice is a size-adjustable device that randomly stimulates, via vibration, regions of the foot. Users respond based on whether they detect the stimulation, indicating potential loss of sensation that would occur with PN. Acquired data will be presented in a simple graphical interface. Initial prototype testing demonstrates that NeuroNotice can successfully determine a difference between healthy and simulated symptomatic feet, thereby allowing for frequent tracking of PN and supporting physicians’ continuous monitoring of neuropathy. deSTIgma: A Digital STI Test Recommendation Platform Susanna Baek, Katharyn Fatehi, Andy Garcia, Vivian Shi, Ruxandra Tonea Despite the many medical advances of the last decade, sexually transmitted infections and diseases (STIs) continue to pose a significant public health issue, with cases increasing continuously for 7 years up to 2020. STI testing, which typically requires an in-person clinic visit, can be inaccessible due to time, travel, and financial limitations. Due to a lack of education and awareness, STIs are also highly stigmatized. The deSTIgma STI Test Recommendation Digital Platform streamlines the STI test-seeking process with a test recommendation questionnaire, clinic map, and educational resources in an app and website. The questionnaire uses relevant medical history, sexual activity history, and symptoms to inform and guide users to appropriate tests and resources in NYC. The machine-learning-based algorithm, stored on a HIPAA approved platform, may be trained with real patient data, pending IRB approval. deSTIgma aims to make STI testing an easily accessible component of regular healthcare for all. 8
Biomedical Engineering budDLS: Buddy for Daily Living Skills Kaitlin Abrantes, Amy Jang, Hyunjee Lim, Kelly Pu, Joa Yun Autism Spectrum Disorder (ASD) is a developmental disability affecting 1 in 44 children in the U.S. Although symptoms vary, ~90% of children with autism struggle to learn daily living skills (DLS) like hand washing and toileting due to difficulties with task sequencing, transferring skills from school to home, and initiating independently. In particular, atypical sensory behavior can result in excessive playing or avoidance of household liquids. The burden is on caregivers to supervise or use hand-over-hand assistance to ensure successful and safe completion of DLS. Children with ASD and their caregivers need a solution that enhances independence during household tasks requiring the use of hygienic liquids. The budDLS dispenser provides a multimodal solution: (1) a dispenser that locks to prevent excess pumping, (2) combination-locked liquid reservoir to prevent pouring liquids out of a bottle, and (3) built-in screen that displays stepby-step instructions and responds to user interactions to teach DLS. LUMA Jui Buamahakul, Leanne Pichay, Justin Saintil, Pavin Sethbhakdi, Joanne W. Wang A root canal procedure is a mechanical and chemical intervention that treats dental pulp infections. It relies on chemical irrigants such as sodium hypochlorite (NaOCl) to sterilize the canal after the removal of infected material. However, NaOCl’s cytotoxicity prevents dentists from irrigating within 2-4 mm of the tooth’s apex, where the majority of bacteria resides, leading to a 35% reinfection and retreatment rate. To address these shortcomings, our Luma device leverages photodynamic therapy, using the combination of a photosensitizer with a high-powered laser to eradicate bacteria. The Luma device seamlessly integrates into the root canal protocol, clamping onto the dental dam isolating the tooth. Here, it irradiates the root canal over a period of minutes, effectively disinfecting the tooth without adverse effects to surrounding tissue. Initial testing indicates that Luma is capable of reaching the energy density required to eliminate more than 97% of most reinfection-causing dental bacteria. 9
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