AN INTERNATIONAL JOURNAL OF TROPICAL & TRAVEL MEDICINE
AN INTERNATIONAL JOURNAL OF TROPICAL & TRAVEL MEDICINE
AN INTERNATIONAL JOURNAL OF TROPICAL & TRAVEL MEDICINE
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<strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
<strong>AN</strong> <strong>INTERNATIONAL</strong> <strong>JOURNAL</strong> <strong>OF</strong><br />
<strong>TROPICAL</strong> & <strong>TRAVEL</strong> <strong>MEDICINE</strong><br />
ISSN 1448-4706<br />
Volume 12 Supplement 1<br />
IN THIS ISSUE<br />
SUPPLEMENT 1<br />
THE TOWNSVILLE HOSPITAL <strong>AN</strong>D JAMES COOK UNIVERSITY,<br />
SCHOOL <strong>OF</strong> <strong>MEDICINE</strong> <strong>AN</strong>D DENTISTRY RESEARCH SYMPOSIUM<br />
FRIDAY 14 OCTObER 2011<br />
RObERT DOUgLAS AUDITORIUM,<br />
THE TOWNSVILLE HOSPITAL, AUSTRALIA<br />
• Editorial<br />
• SympoSium program<br />
• invitEd SpEakEr BiographiES<br />
• kEynotE addrESS aBStract<br />
• oral aBStractS<br />
• poStEr aBStractS<br />
• diScuSSion papEr<br />
ACTM MEMBERSHIP APPLICATION<br />
Official Journal of The Australasian College of Tropical Medicine<br />
Volume 12 Supplement 1 October 2011<br />
1 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
S1
Officers of The Australasian College of<br />
Tropical Medicine<br />
President<br />
Associate Professor David Porter<br />
Vice President<br />
Dr Kym Daniell<br />
Honorary Secretary<br />
Dr Richard bradbury<br />
Honorary Treasurer<br />
Professor Peter A. Leggat<br />
Immediate Past President<br />
Associate Professor Tim Inglis<br />
Council Members<br />
Dr Vlas Efstathis, OAM, RFD, Associate Professor<br />
John Frean, Dr Sue Heydon, Associate Professor<br />
Wayne Melrose, Associate Professor geoff Quail,<br />
Associate Professor Marc Shaw,<br />
Professor Richard Speare<br />
Chair, Faculty of Travel Medicine<br />
Dr Jennifer Sisson<br />
Chair, Faculty of Expedition and Wilderness Medicine<br />
Associate Professor Marc Shaw<br />
Chairs of Standing Committees<br />
Dr Vlas Efstathis, OAM, RFD (Disaster Health)<br />
Dr Richard S. bradbury (Medical Parasitology & Zoonoses)<br />
Professor Derek R. Smith (Publications)<br />
Dr Ken D. Winkel (Toxinology)<br />
Secretariat<br />
ACTM Secretariat, PO box 123,<br />
Red Hill QLD 4059 AUSTRALIA<br />
Tel: +61-7-3872-2246<br />
Fax: +61-7-3856-4727<br />
Email: actm@tropmed.org<br />
Website: http://www.tropmed.org<br />
Editorial Board<br />
<strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
Editor-in-Chief<br />
Professor Derek R. Smith<br />
Emeritus Editor-in-Chief<br />
Emeritus Professor John M. goldsmid<br />
Executive Editors<br />
Professor Peter A. Leggat<br />
Associate Professor John Frean<br />
ACTM BULLETIN<br />
Editor ACTM Bulletin<br />
Professor Peter A. Leggat<br />
Sub-Editor<br />
Associate Professor Arun Menon<br />
Board Members and Review Panel<br />
Dr Irmgard bauer, Emeritus Professor Roderick SF<br />
Campbell, AM, Professor David Durrheim, Associate<br />
Professor John Frean, Dr Michael Humble, Associate<br />
Professor Tim Inglis, Professor Justin La brooy,<br />
Professor Ahmed Latif, Dr Alan Mills, Professor John H.<br />
Pearn, AO, RFD, Dr Ken D. Winkel<br />
<strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
<strong>AN</strong> <strong>INTERNATIONAL</strong> <strong>JOURNAL</strong> <strong>OF</strong> <strong>TROPICAL</strong> & <strong>TRAVEL</strong> <strong>MEDICINE</strong><br />
CONTENTS<br />
SUPPLEMENT 1<br />
THE TOWNSVILLE HOSPITAL <strong>AN</strong>D JAMES COOK UNIVERSITY,<br />
SCHOOL <strong>OF</strong> <strong>MEDICINE</strong> <strong>AN</strong>D DENTISTRy RESEARCH SyMPOSIUM<br />
FRIDAY 14 OCTOBER 2011<br />
ROBERT DOUgLAS AUDITORIUM,<br />
THE TOWNSVILLE HOSPITAL, AUSTRALIA<br />
© Copyright 2011 ACTM<br />
OCTOBER 2011<br />
EDITORIAL S1<br />
SyMPOSIUM PROgRAM S2<br />
INVITED SPEAkER BIOgRAPHIES S3<br />
kEyNOTE ADDRESS ABSTRACT S3-S4<br />
ORAL ABSTRACTS S4-S7<br />
POSTER ABSTRACTS S8-S12<br />
DISCUSSION PAPER S13<br />
MEMBERSHIP<br />
ACTM MEMBERSHIP APPLICATION S15-S16<br />
Cover photo: The Australian Institute of Tropical Medicine in 1916 (photo courtesy of James Cook University)<br />
Material published in the Annals of the ACTM is covered by copyright and all rights are reserved, excluding “fair use”, as<br />
permitted under copyright law. Permission to use any material published in the Annals of the ACTM should be obtained in<br />
writing from the authors and Editorial board.
The Townsville Hospital and James<br />
Cook University, School of Medicine<br />
and Dentistry Research Symposium<br />
Friday 14 October 2011 (12:30-4:00pm)<br />
Robert Douglas Auditorium,<br />
The Townsville Hospital<br />
EDITORIAL<br />
Fostering Research in Hospitals<br />
Lynden J. Roberts<br />
Director, Tropical Alliance for Clinical Excellence by Research (TRACER), Townsville Health<br />
Service District, The Townsville Hospital, Townsville<br />
Hospitals have long-provided a fertile environment for medical research.<br />
Much of the knowledge base underpinning modern medicine was derived<br />
from hospital-based research. That hospitals co-locate collections of the<br />
sickest patients and enquiring clinical minds provides a ready explanation.<br />
For reasons of efficiency, hospitals have also traditionally served as the<br />
setting for medical student clinical training. For both of these reasons,<br />
university medical faculties and research institutes have conventionally<br />
sought to co-locate with large hospitals around the world. In Australia, this<br />
model meant that a select group of “university teaching hospitals” evolved.<br />
These delivered high concentrations of academically active clinicians<br />
attached to the hospitals, and inevitably generated highly productive<br />
research environments.<br />
Much has changed. Research has become vastly more complex and<br />
specialized requiring full-time research commitments, substantial funding,<br />
and collaborating teams. The romantic idea that an astute clinician might<br />
still make a major research discovery by isolated pottering in research,<br />
without much time or resources, is unfortunately fanciful. Separately,<br />
university medical schools have been increasingly providing clinical training<br />
in community settings. this has been driven by the need to find sufficient<br />
clinical resources to train students, but also out of a desire to improve the<br />
breadth of clinical exposure during training, and with the realistic hope that<br />
community-based training might encourage more people to choose to work<br />
in those settings. Our own James Cook University has provided national<br />
leadership in this area by demonstrating that this works. Lastly, hospitals<br />
have been increasingly focused on optimizing the efficiency of the care they<br />
provide. This has meant that clinical service demands consume an everincreasing<br />
percentage of a clinician’s time. While all of these drivers of<br />
change have sound underlying rationales, their combined effect has seen<br />
the fading of academic life from modern Australian hospitals.<br />
Yet, there remain two compelling reasons for fostering a culture of<br />
research in hospitals. First, the hospitals traditional advantage of<br />
clustering the sickest patients remains. When considering potential<br />
impact, undertaking research on the sickest patients makes for a large<br />
potential research yield and finding them all in one place makes the work<br />
efficient. Second, and perhaps as important, a culture of research actually<br />
underpins the quality of clinical care and of clinical education. Only a<br />
research culture can deliver the enquiring minds with the skills to ask and<br />
answer the contemporary health questions, to challenge dogma, and to<br />
drive continuous improvements. Without a culture that teaches and applies<br />
these skills, our hospitals become factories for the sick filled with ‘factory’<br />
workers. this factory model might seem superficially appealing to generic<br />
managers, but it fails to serve healthcare efficiently or effectively. rather,<br />
we need hospitals to be flexible, adaptive and self-improving entities filled<br />
with flexible, adaptive, and self-improving staff; only an organization-wide<br />
culture of enquiring minds can deliver this. Although these advantages<br />
of hospital-based research are compelling, our research attention must<br />
Volume 12 Supplement 1<br />
also embrace those long-neglected research areas of community health,<br />
underserved populations, disease prevention, and the new problems of<br />
chronic disease, workforce shortage and health services research to name<br />
a few; but abandoning medical research in hospitals altogether represents<br />
a sizeable opportunity lost.<br />
There is some reason to be optimistic. There is growing recognition of<br />
the importance of embedding research within integrated teaching hospital<br />
environments. influential australian health leaders have pointed to the<br />
high correlation between the quality of clinical care, education, and the<br />
presence of research at the best institutions throughout the world and<br />
have called for similar strategies here. 1;2 Our NHMRC in its strategic plan<br />
2010-2012 has one of its objectives as “integrating the conduct of research<br />
with high quality education of health professionals and with the care of<br />
patients”. 3 Other countries are well ahead though. In fact, the USA has<br />
been integrating patient care, research and education well ever since the<br />
Flexner report laid out the strategy in 1910! In the UK, similar concerns to<br />
those outlined above have driven major reforms of the NHS. These have<br />
delivered substantial new funding targeting the clinical and translational<br />
end of health research. Tellingly, the UK Health Minister has recently been<br />
explicitly tasked with promoting research within the health portfolio. 4 All of<br />
these authorities highlight the value of bringing research experiences into<br />
training across the training spectrum and maintaining them throughout the<br />
clinical working life.<br />
Pleasingly, a local response is underway. The Townsville Health Service<br />
District has established three streams of research activity in nursing,<br />
allied health, and medical disciplines. To bolster the medical stream, the<br />
District has recently appointed a Director of Clinical Research to lead a<br />
new organization TRACER – the TRopical Alliance for Clinical Excellence<br />
by Research. broadly, the aims of these three research streams are to lead<br />
and support research within the District by building research capacity and<br />
attracting resources, but they have a particular focus on research activities<br />
that have visible ties to patient outcomes. The time is ripe for these<br />
initiatives. This year’s NQ Clinical Research Symposium shows that there<br />
is already a growing local base of research activity on which to build. Next<br />
year the Symposium will form part of a multidisciplinary research week for<br />
the District, which will come on the back of JCUs “Celebrating Research”<br />
month of activities. I encourage you all to get involved and join the exciting<br />
world of knowledge-making.<br />
References<br />
1. Penington Dg. Rediscovering university teaching hospitals for Australia. Med J Aust 2008; 189, 332-5.<br />
2. Van Der Weyden Mb. The viability of Australia’s teaching hospitals. Med J Aust 2008; 189, 330-1.<br />
3. Anderson W, good M. National Health and Medical Research Council Strategic Plan 2010-2012. Available online<br />
at: http://www.nhmrc.gov.au/guidelines/publications/nh132 (Accessed: 13 September 2011)<br />
4. Sanderson A. government response to the NHS Future Forum. Available online at: http://www.dh.gov.uk/prod_<br />
consum_dh/groups/dh_digitalassets/documents/digitalasset/dh_127578.pdf (Accessed: 13 September 2011)<br />
Acknowledgements<br />
We would like to formally acknowledge all the members of the<br />
2011 Organising Committee who kindly assisted in making this<br />
year’s Symposium possible: Rebecca Evans, Jenine Lawlor, Lynden<br />
Roberts, Shantae Ryle, Sabe Sabesan and Laura Simpson. We would<br />
also like to acknowledge the assistance of the following members<br />
of the Townsville Hospital Research Steering Committee, who have<br />
graciously given their time: Peter Aitken, Rhys Edwards, John Evans,<br />
Jeremy Furyk, Sarah Larkins, Richard Murray, Robert Norton, Carl<br />
O’Kane, David Porter, John Reilly, Kunwarjit Sangla and Andrew White.<br />
This special supplementary issue of the Annals of the Australasian<br />
College of Tropical Medicine (AACTM) was edited by Derek R. Smith<br />
and glenn Courtenay from the University of Newcastle, Ourimbah,<br />
with graphic design undertaken by Jerry Liu from Jerry Liu Design &<br />
Photography, brisbane. Thanks also to the AACTM Executive Editorial<br />
board of John M. goldsmid, Peter A. Leggat and John Frean.<br />
1 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
S1
SyMPOSIUM PROgRAM<br />
The Townsville Hospital and James Cook University,<br />
School of Medicine and Dentistry Research Symposium<br />
Friday 14 October 2011 (12:30-4:00pm)<br />
Robert Douglas Auditorium, The Townsville Hospital<br />
TIME TOPIC SPEAkER<br />
12:00 LUNCH<br />
12:30 Welcome Address<br />
12:35<br />
Introduction and Overview<br />
An epidemiological review of invasive Staphylococcus aureus infections in children of Far<br />
North Queensland<br />
Dr Andrew Johnson, CEO,<br />
Townsville Health Service District<br />
Dr Lynden Roberts, Chairperson,<br />
2011 North Queensland Medical Research<br />
Symposium<br />
Ms Tiarna Ernst<br />
12:40 injury and illness on the West coast trail: Still the graveyard of the pacific? Dr Jonathon Malo<br />
12:45 Exposure to Coxiella burnetii in Townsville Dr Katie Eales<br />
12:50<br />
12:55<br />
A study of outcome following Percutaneous Coronary Interventions (PCIs) in the Aboriginal<br />
and Torres Strait Islanders (ATSIs) population of North Queensland<br />
Maintaining intern learning in the ED despite a 50% increase in intern numbers: Can a<br />
structured learning program be part of the answer?<br />
Dr Akhlaq Khan<br />
Dr Catriona Slater<br />
1:00 Retinal vessels in low birth-weight babies Mr Leo Hartley<br />
1:15<br />
Diagnosing CT-negative spontaneous (non-traumatic) subarachnoid haemorrhage across<br />
Australasia: Perceived versus actual practice<br />
Dr Cassandra Farris<br />
1:30 Keynote address: Then and now: 64 years a Surgeon Emeritus Professor Tom Reeve<br />
2:15 AFTERNOON TEA<br />
2:45 Intra- and inter-observer consistency in visual inspection for “xanthochromia” Ms Donna Rudd<br />
2:55 Improving discharge summaries through education Dr Lesley Stainkey<br />
3.00 glycaemic control post open heart surgery at the The Townsville Hospital Dr Ching-Siang Cheng<br />
3:05<br />
a longitudinal study of the career paths of the first James cook university medical school<br />
graduates<br />
Dr Aileen Traves<br />
3:20 The Diabetic Host: Tropical paradise for a killer bug Dr Jodie Morris<br />
3:35 Hospital access block - Exit block interaction Dr Paul goldstraw<br />
3:50 bacteraemias in North Queensland Dr Robert Norton<br />
4:05 Improving rural and indigenous cancer outcomes: A clinical research perspective Dr Sabe Sabesan<br />
4:20 Closing Address<br />
4.25<br />
WINE <strong>AN</strong>D CHEESE<br />
AWARDINg <strong>OF</strong> PRIZES<br />
Associate Professor Richard Murray, Dean<br />
and Head of School, School of Medicine<br />
and Dentistry, James Cook University<br />
S2 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM October 2011
INVITED SPEAkER BIOgRAPHIES<br />
Volume 12 Supplement 1<br />
Emeritus Professor Tom Reeve, AC, CBE.<br />
Tom Reeve, AC, CbE, is an Emeritus Professor<br />
in Surgery of the University of Sydney. Professor<br />
Reeve graduated from the University in 1947 and<br />
after working in Sydney entered general Practice in<br />
Collinsville, North Queensland. In July 1950 he went<br />
to Albany Medical College in upstate New York and<br />
completed training in general and Thoracic Surgery.<br />
Returning to Sydney in 1956, he worked as a Surgical<br />
Research Fellow in the Unit of Clinical Investigation at Royal North Shore<br />
hospital. in 1958 he became certified by the american Board of Surgery and<br />
in 1967 became a Fellow of the Royal Australasian College of Surgeons. In<br />
1961 he was appointed as a Senior Lecturer in the Department of Surgery,<br />
The University of Sydney, based at Royal North Shore Hospital. He built on a<br />
Thyroid Unit to develop a strong Endocrine Surgical Unit, which continues.<br />
He also developed a strong association in the applied research activities of<br />
the Ultrasonics Institute and became involved in clinical ultrasound during<br />
its development for the study of the breast, thyroid and parathyroid glands,<br />
working with Dr george Kossoff, the Institute’s Director and Dr Jack Jellins,<br />
taking the modality into clinical practice. He was Chairman of Surgery at the<br />
University from 1982 until 1988. He Chaired the Northern Sydney Health<br />
Area from 1988-1996. He was awarded Commander of the Order of the british<br />
Empire - for services to Medicine in 1973 and a Companion to The Order<br />
of australia in 1994 ‘For service to medicine and to academic and clinical<br />
surgery, particularly in the field of endocrinology’. on retirement, tom reeve<br />
became President of the Royal Australasian College of Surgeons and has had<br />
a role in best Practice and Quality activities at both a clinical and administrative<br />
level. In 1993 he prepared a report “Quality Assurance and Utilisation<br />
Review in Hospitals” for the Department of Health & Human Services.<br />
He was appointed by the Australian Cancer Society (now known as Cancer<br />
council australia) as Executive officer, australian cancer network in late<br />
1993. He was Chair of the Working Party that developed “Clinical guidelines<br />
for the Management of Early breast Cancer” for the NHMRC. These were the<br />
first evidence-based cancer management guidelines produced in australia.<br />
Professor Reeve developed a database in Thyroid and Parathyroid Surgery<br />
commencing in 1957 and continues to the present. He is still active with a<br />
number of young people in publishing papers in the thyroid field. he continues<br />
to publish papers in refereed journals, including recent contributions<br />
to papers on ‘Surgical trends in the management of thyroid lymphoma’ and<br />
‘increasing incidence of thyroid cancer is due to increased pathologic detection’.<br />
He holds honorary membership of the American Surgical Association,<br />
kEyNOTE ADDRESS ABSTRACT<br />
Then & Now: 64 Years a Surgeon<br />
Emeritus Professor Tom Reeve, AC, CBE.<br />
Professor of Surgery, University of Sydney<br />
being a surgeon is a great privilege. being a surgeon for 64 years is an even<br />
greater privilege. As a child, I saw Australia to be growing and beginning to<br />
establish the institutions that are now an important part of our daily fabric. A<br />
national parliament was opened. The nation survived a great and degrading<br />
depression. It had distinguished itself in War. Nationhood had been achieved<br />
in a demanding crucible and its achievements continue. Medical school was<br />
still heavily dependent on Anatomy as the major subject in the curriculum.<br />
The elements of history taking and clinical examination were the basis of<br />
clinical medicine. Investigations were rather rudimentary as compared to<br />
what is now available.<br />
the Coller Society and the Alpha Omega Alpha (AΩA) Medical Honor Society.<br />
He is an honorary MD of the University of Sydney and Honorary Fellow of<br />
the American, Canadian, South African and Philippine Colleges of Surgeons.<br />
He enjoys interacting with his colleagues, travel, reading and weekends in<br />
the garden.<br />
Dr Sabe Sabesan<br />
Dr Sabe Sabesan, MbbS, FRACP, is the Director of<br />
Medical Oncology at the Townsville Cancer Centre,<br />
Townsville Hospital and the convenor of cancer education<br />
at the School of Medicine and Dentistry at the<br />
James Cook University. As a member of the Oncology<br />
Education Committee of the Cancer Council of<br />
Australia, he has contributed to the development of<br />
ideal oncology curriculum for medical students and<br />
published in the area of medical education. He was a member of the <strong>AN</strong>Z<br />
Melanoma and Prostate Cancer guidelines Writing Committees and has written<br />
chapters relating to medical therapies in both cancers. In his Queensland<br />
Health role, he pioneered the largest teleoncology network in the country<br />
for which his department was a finalist in the Qld premier’s award for Excellence<br />
in Service Delivery in 2010. He has published, presented and conducted<br />
workshops in the area of rural and indigenous health and telehealth.<br />
SyMPOSIUM CHAIR<br />
Dr Lynden J. Roberts<br />
Dr Lynden J. Roberts, MbbS, PhD, FRACP, is the<br />
newly appointed Director of Clinical Research for the<br />
Townsville Health Service District. After graduating<br />
with an MbbS from the University of Melbourne in<br />
1994, he completed a PhD in Immunogenetics at the<br />
Walter and Eliza Hall Institute of Medical Research in<br />
2000. Currently Director of Rheumatology, his previous<br />
appointments include Director of Physician<br />
Training, and the Director of Internal Medicine at the Townsville Hospital,<br />
and Senior Lecturer in the Department of Medicine, University of Melbourne.<br />
dr roberts looks forward to helping raise the profile, quality and quantity of<br />
clinical research in North Queensland.<br />
Immediate postgraduate education was quite rudimentary and most specialisation<br />
was begun in and from general practice. To move from a city hospital<br />
to a country or regional area was commonplace and many doctors who later<br />
became specialists commenced their progress along the training path in this<br />
way. good understanding between the local community and doctors was<br />
strong and patient expectations were less than they are now. Most graduates<br />
who wanted to become highly specialised went to train in England. The odd<br />
one chose to go the uSa only to find that their ambitions were overturned<br />
by the Korean War which drained American hospitals of the young surgeons<br />
and surgical trainees. Trainees in US teaching and regional hospitals were<br />
well taught and expected to be involved in research activities - a feature being<br />
considered in Australian programmes although the desirable extent is<br />
still not determined.<br />
3 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
S3
Returning to Australia allowed the study of some areas which would be different<br />
today. Some matters came along unexpectedly at the time. Community<br />
generosity allowed a surgeon to advance overseas to acquire training<br />
in the use of cytotoxic drugs and their use in treatment before the arrival<br />
of medical oncologists who quickly transformed the field. the compulsory<br />
mass chest x-ray survey for detection of tuberculosis yielded signs of other<br />
pathology than just in the chest and allowed a useful epidemiological study<br />
into to other pathological processes. Opportunities also presented in the<br />
field of diagnostic ultrasound which was materially advanced by members<br />
of the Ultrasonics Institute. At the time, there was a strong realisation of the<br />
important role played by training and the practiced management of professional<br />
matters by strong mentors. Every young doctor can benefit from “an<br />
experienced trusted adviser, counsellor and guide”.<br />
ORAL ABSTRACTS<br />
The Townsville Hospital and James Cook University,<br />
School of Medicine and Dentistry Research Symposium<br />
Friday 14 October 2011 (12:30-4:00pm)<br />
Robert Douglas Auditorium, The Townsville Hospital<br />
An Epidemiological Review of Invasive Staphylococcus aureus Infections<br />
in Children of Far North Queensland<br />
Tiarna Ernst<br />
School of Medicine and Dentistry, James Cook University, Townsville<br />
Aims: The objective of this study was to identify the prevalence of invasive<br />
Staphylococcus aureus infections within Far north Queensland, australia;<br />
in addition to obtaining epidemiological data of the patient demographics,<br />
clinical consequences and severity of these infections. Methods: A<br />
retrospective clinical record audit of all 172 paediatric patients admitted<br />
to Cairns base Hospital between 1 st January 2000 and 31 st December 2009<br />
with an invasive Staphylococcus aureus infection. High resolution melting<br />
analysis was performed on a subsample population of 48 patients for<br />
clonal complex (CC) identity and Panton Valentine Leukocidin (PVL) toxin<br />
production. Results: The rate of admission to Cairns base Hospital with<br />
an invasive S. aureus infection increased over the 10 year study period.<br />
there was a significant increase in the proportion of infections caused by<br />
ca-mrSa. indigenous children were significantly more likely to have a ca-<br />
MRSA infection than non-indigenous children. On univariate analysis, PVL<br />
positive infections were significantly more likely to have longer hospital<br />
stay, higher C-reactive protein levels, severity scoring and ICU admission.<br />
cc30 South West pacific was the most predominant clone. Five pvl positive<br />
cc1 isolates were identified. Conclusion: ca-mrSa has significantly<br />
contributed to an increase in paediatric invasive S. aureus infections within<br />
Far North Queensland. There appears to be a heavy burden of invasive S.<br />
aureus infections on the indigenous child population. A larger subsample is<br />
required to confidently comment on the severity of pvl positive S. aureus<br />
infections. There is observation of an increase in PVL positive CC emerging<br />
within Far North Queensland.<br />
Injury and Illness on the West Coast Trail: Still the graveyard of<br />
the Pacific?<br />
Jonathan A Malo¹ and Eiman Zargaran²<br />
¹The Townsville Hospital, Townsville<br />
²Parks Canada, Vancouver, Canada<br />
Objective: To review the epidemiology of injuries, illnesses, and causes<br />
of evacuations on the WCT and make recommendations for improving<br />
One mentor in 1955 advised that a database be established in an area of<br />
surgical speciality. He said, “Computers are coming - be ready”. Little did he<br />
know that there would be a testing of personal interest and tenacity as there<br />
would be no usable results for at least three years. However, a database in<br />
Endocrine Surgical Procedures was commenced in 1957 and continues to<br />
this day. It took 24 years before a single observation produced from the database<br />
led to change in the world. Practice results are reported. The resultant<br />
activities can be performed by trained surgeons in the cities and provinces.<br />
Professionalism and attributes of clinical surgical researchers can be discussed.<br />
Surgeons, however, need to carefully maintain their role in a highly<br />
competitive research environment despite frequent criticism of their role.<br />
participant safety. Methods: parks canada staff provided de-identified<br />
public safety occurrence data within the WCT from 2005 to 2010. These<br />
reports were retrospectively reviewed and the relevant data was extracted.<br />
Only reports involving hikers during the May 1st to September 30th hiking<br />
season were included. The two-proportion z-test was used to determine<br />
statistical significance. Results: We reviewed 457 occurrence reports of<br />
which 310 met inclusion criteria, corresponding to an incident rate of 1<br />
per 104 hikers. this was significantly increased (p
and rainfall data was collected. Results: Serological evidence of exposure<br />
to C. burnetii was demonstrated in 243 patients, including 92 patients with<br />
confirmed acute disease. clustering of cases in suburbs of townsville<br />
was demonstrated with a rate of 24.9 per 100,000 population in the most<br />
affected area. A seasonal peak was found, with the greatest number of cases<br />
observed in May. Conclusion: to our knowledge, this is the first study to<br />
demonstrate an association between rainfall and the incidence of Q fever in<br />
North Queensland. Townsville has historically been closely associated with<br />
cattle farming and several old cattle grazing sites now lie within residential<br />
zones. Furthermore, C. burnetii is known to commonly infect local wildlife<br />
and tick populations. Possible reasons for the seasonal variation in acute<br />
cases are discussed and further areas for research suggested.<br />
A Study of Outcome following Percutaneous Coronary Interventions<br />
(PCIs) in the Aboriginal and Torres Strait Islanders (ATSIs)<br />
Population of North Queensland<br />
Akhlaq Khan, Vishwanathan Venkatachalam, Raibhan Yadav and<br />
Dinesh Sivananthan<br />
Department of Cardiology, The Townsville Hospital, Townsville<br />
Aim: A retrospective observational analysis of immediate, early & late<br />
outcomes following PCIs in the ATSIs population of North Queensland.<br />
Methods: 254 PCIs were performed on 190 ATSIs patients from May 2006<br />
to February 2011. Details were obtained from the Townsville Hospital<br />
Cardiology Database (Cardiobase) and hospital charts. The sample<br />
population had a wide geographic distribution. Results: 195 hospitalization<br />
with ischemic heart disease (IHD) comprised of 122 men (63%) and 73<br />
women (37%). 234 urgent PCIs were performed on various coronary<br />
arteries included 224 stent deployment (95.72%) and 10 angioplasties<br />
(4.27%). 241 (94%) first pci procedure were performed in 132 men (55<br />
%) & 109 women (45%) and 19 had repeat PCIs depending on the nature<br />
of indication. 101 (53%) patients were followed up (men = 60 [51%] &<br />
women = 41 [56%]) for an average period of 5 yrs at the Townsville hospital.<br />
Overall immediate procedural success was (94.09%) and Immediate PCIrelated<br />
complications were acute re-occlusion, residual thrombus, residual<br />
stenosis, coronary artery dissection and VF arrest were 0.39%, 0.78%,<br />
1.18%, 1.18% and 1.57% respectively. Late PCI-related complications<br />
including early Instent thrombosis, subacute instent restenosis, late<br />
Instent thrombosis and late instent restenosis was 0.52% for each<br />
respectively. Overall M.A.C.C.E was 0.52% at 30 days, 6 months and at 1<br />
year respectively. Conclusion: In 254 PCIs performed on ATSI population,<br />
an excellent immediate procedural success rate was achieved with a low<br />
rate of immediate, early & late PCI related-complications. Medication noncompliance<br />
remained a significant challenging issue. however, the overall<br />
M.A.C.C.E was low.<br />
Maintaining Intern Learning in the ED despite a 50% Increase in<br />
Intern Numbers: Can a Structured Learning Program be Part of the<br />
Answer?<br />
Catriona Slater, Michelle Lees and Jenine Lawlor<br />
Post Graduate Medical Education Unit, The Townsville Hospital, Townsville<br />
Introduction: the ‘more learning for interns in Emergency’ (moliE)<br />
program was designed to provide targeted Emergency Medicine<br />
education, while increasing the capacity of the Emergency Departments<br />
to accommodate interns. Objective: To assess the effects of a structured<br />
learning program on interns’ self-rated confidence in practical and<br />
professional skills. Setting and Participants: The MoLIE program was<br />
implemented in early 2010 in the Townsville Hospital ED, coinciding with<br />
a 50% increase in intern numbers. it consisted of 8 hours of ‘off the floor’<br />
consultant-led case-based teaching plus 2 to 4 shifts of additional ‘on<br />
the floor’ consultant supervision per week. Methods: Data was collected<br />
prospectively for 2 years from ED interns at the beginning and end of each<br />
ED term, using a 25 item 5-point Likert scale questionnaire, addressing<br />
interns’ self-reported confidence in practical and professional skills. the<br />
Volume 12 Supplement 1<br />
MoLIE program was implemented 1 year into the data collection period.<br />
Summed likert Scores were calculated and the change in confidence in<br />
both practical and professional skills was compared. Results: Interns<br />
consistently reported an increase in confidence regarding their practical<br />
and professional skills during a term in Emergency medicine. no significant<br />
difference was found for the increase in confidence between the 2009 and<br />
2010 cohorts of interns. Conclusion: The structure of the MoLIE program<br />
has allowed for a significant increase in the capacity of the townsville<br />
Hospital to accommodate interns, without compromising the educational<br />
experience of an ED term, as perceived by the interns. We present the<br />
MoLIE program as a viable model for accommodating the rapid expansion<br />
in intern numbers in the ED.<br />
Retinal Vessels in Low-Birth-Weight Infants<br />
Yoga Kandasamy¹, Roger Smith¹, Ian Wright2 and Leo Hartley¹<br />
¹Department of Neonatology, The Townsville Hospital, Townsville<br />
²School of Medicine and Dentistry, James Cook University, Townsville<br />
Aims: The purposes of this study were to determine the normal retinal<br />
microvasculature measurements in human infants who are born at<br />
term and to determine whether birth weight influences measurements<br />
of retinal microvasculature. Study Design: Retinal arteriole and venule<br />
measurements were obtained in a cohort of 24 infants who were born at<br />
term. Digital images of both retinas were obtained using a digital retinal<br />
camera after pupillary dilation. Results: In all, 24 newborn infants born at<br />
term (12 females and 12 males) were analysed in this study. The measured<br />
retinal arteriole diameters were 66.8–147.8 μm (mean, 94.2±19.6 μm), and<br />
the venule diameters were 102.0-167.8 μm (mean, 135.2±19.1 μm). Seven<br />
babies in the sample had low birth weight, while 17 babies were born<br />
with normal weight. babies with lower birth weights had larger arteriole<br />
(113.1±17.9 μm vs. 86.4±14.4 μm; p=0.0009) and venule diameters<br />
(151.7±14.9 μm vs. 128.4±16.9 μm; p=0.0040). Conclusion: Retinal<br />
venules and arterioles in low-birth-weight babies are larger compared<br />
to those of normal-birth-weight babies. We postulate that the difference<br />
observed in our study was due to in utero pathophysiological changes<br />
that occurred in the cerebral circulation of growth-restricted foetuses.<br />
Reprinted from the Journal of Perinatology (advance online publication, 2011: doi: 10.1038/<br />
jp.2011.118). Full version available online at: http://www.nature.com/jp/journal/vaop/ncurrent/<br />
full/jp2011118a.html<br />
Diagnosing CT-negative Spontaneous (non-traumatic)<br />
Subarachnoid Haemorrhage across Australasia: Perceived versus<br />
Actual Practice<br />
Cassandra Faris, Ryan Duell, Laurence Marshman, Jason McMilen,<br />
Felix Ng, David Anderson and Eric guazzo<br />
Department of Neurosurgery, The Townsville Hospital, Townsville<br />
Aim: The diagnosis and management of spontaneous subarachnoid<br />
haemorrhage (sSah) with normal plain ct findings is controversial.<br />
Interventional risks may outweigh natural history risks for unruptured<br />
aneurysms: proof of sSAH is therefore usually sought by LP. Unfortunately,<br />
variation is possible in CSF sampling timing, CSF diagnostic criterion (DC)<br />
definition, or cSF dc detection. We aim to document current laboratory<br />
practice across australasia; the attitudes and knowledge of neurosurgical<br />
registrars towards cSF-sSah diagnosis; and their familiarity with local<br />
laboratory practice. Methods: N=51 laboratories (n=22 in neurosurgical<br />
units) across Australasia were surveyed regarding their current practice in<br />
dcdefinitionanddcdetectionmethodologywithcSF-sSahdiagnosis.n=55<br />
neurosurgical registrars were then surveyed across each unit to document:<br />
1) their knowledge and attitudes towards CSF-sSAH diagnosis, and 2) their<br />
familiarity with local laboratory practice. Results: our results confirmed<br />
maximal heterogeneity (both inter- and intra-state) in laboratory CSF-sSAH<br />
diagnosis: in both dc definition (3/3 definitions practiced) and dc detection<br />
methodology (6/6 methodologies practiced). there was also significant<br />
5 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
S5
heterogeneity in knowledge and attitudes amongst neurosurgical registrars<br />
towards cSF-sSah diagnosis (65% considered [un-recommended] ‘Xi’<br />
the desired dc), significant heterogeneity in perceived sampling timing<br />
(56% did not cite 12hrs) or sampling practicalities (1.8% considered these<br />
irrelevant), whilst 84% incorrectly identified their own laboratory’s dc<br />
definition and a further 42% incorrectly stated their own laboratory’s dc<br />
detection methodology. Conclusion: CSF-sSAH diagnosis in CT-negative<br />
patients in neurosurgical units across Australasia is currently confused:<br />
both in principle, and in practice. National guidelines are required for CSF<br />
dc definition, cSF dc laboratory detection methodology, and in the timing<br />
and practicalities of CSF sampling.<br />
Intra- and Inter-Observer Consistency in Visual Inspection for<br />
‘Xanthochromia’<br />
Ryan Duell¹, Cassandra Faris¹, Donna Rudd², Laurence Marshman¹,<br />
David Anderson¹ and Eric guazzo¹<br />
¹Department of Neurosurgery, The Townsville Hospital, Townsville<br />
²Department of Physiology, James Cook University, Townsville<br />
Aim: Where CT is negative after putative subarachnoid haemorrhage (SAH),<br />
a lumbar puncture (LP) is usually performed. Whilst spectrophotometry to<br />
measure cerebrospinal fluid (cSF) bilirubin is the currently recommended<br />
diagnostic standard, some laboratories continue to perform visual<br />
inspection to assess “xanthochromia” (viX) in the cSF supernatant.<br />
However, to our knowledge, no study to date has demonstrated the intraand<br />
inter-observer consistency of viX. We aim to demonstrate the intraand<br />
inter-observer consistency of viX. Methods: A laboratory study was<br />
devised to simulate viX analysis clinically. a series of tubes with mock<br />
CSF containing increasing concentrations of added haemoglobin (0, 0.5,<br />
1.0, 2.5, 5.0 and 6.0 g/L), bilirubin (0, 0.34, 1.0, 1.5, 3.0 and 6.0 umol/L)<br />
and albumin (0.3 and 2.0 g/L), were subsequently mixed to simulate<br />
varying degrees of blood, protein and bilirubin contamination from ‘clear’<br />
through to ‘maximally contaminated’ in both cases. n=26 non-colourblind<br />
observers (M11, F15) were then randomly assigned each known<br />
mixture on two separate occasions: in two separate rooms of significantly<br />
differing ambient luminosity (400-430 versus 950-1020lux). viX was<br />
performed against a white background in all four circumstances. Results:<br />
intra-observer viX consistency was poorer in males than in females.<br />
intra-observer viX consistency was also poorer in lower than in higher<br />
ambient luminosity. inter-observer viX consistency was significantly<br />
poorer than intra-observer consistency. Inter-observer consistency was<br />
also significantly poorer in lower ambient luminosity: especially regarding<br />
‘orange’ hues. in general, with increased haemoglobin and bilirubin<br />
concentrations, ‘red’ hues consumed ‘yellow’ hues. Conclusion: Even<br />
excluding colour blindness (present in 8% males), both poor ambient<br />
illumination and male sex appear to adversely affect viX consistency. viX<br />
inconsistency is therefore clinically significant. viX should be abandoned<br />
at a National level in favour of more objective analysis for CSF bilirubin.<br />
Light in the Interior of a Tropical Hospital - Could This Affect Patients’<br />
Circadian Rhythm?<br />
Sandra Burton and Paul goldstraw<br />
Dementia-Delirium Ward, Gerontology Services, The Townsville Hospital, Townsville<br />
Introduction: The inner environment of buildings in the Tropics is a<br />
balance between heat and ventilation, shade and light. This may result in<br />
low internal light levels, below the required 2000 lux to maintain circadian<br />
rhythm and mood. Patients with delirium and dementia easily lose that<br />
rhythm. Night disorientation is a major problem in hospitals. Aim: This<br />
study was undertaken to evaluate light levels inside a modern hospital in<br />
the tropics as the first phase of a project on light and circadian rhythm<br />
in at risk patient groups. Methods: Light level was measured in lux by a<br />
TES Electrical Electronic Corporation Light Meter (model number 1330).<br />
Recordings were taken during 12-1400 hours in the medical wards of TTH.<br />
Results: The average lux level in single patient rooms of the Dementia-<br />
Delirium ward was mean 267, the four bed room was 536 lux. The common<br />
patient areas recorded an average of 90, with the dining room at 694 lux.<br />
The future ward area recorded similar low levels. general Medical Ward 4<br />
bed bays recorded 110-460, corridors and staff write-up areas 134 lux.<br />
Conclusion: all ward areas had low levels of light; sufficiently low enough<br />
to affect circadian rhythm of patients, particularly those at risk of poor<br />
circadian entrainment. This is worthy of further study.<br />
glycaemic Control Post Open Heart Surgery at the Townsville Hospital<br />
Ching-Siang Cheng and Wei-Yan Tan<br />
The Townsville Hospital, Townsville<br />
Aim: The objective of the our study is to study and document the patterns<br />
of blood glucose control post cardiac surgery at The Townsville Hospital,<br />
and to contribute to the guidelines for blood glucose control for our<br />
post cardiac surgical patients. Methods: Retrospective cohort study of<br />
consecutive diabetic and non-diabetic patients undergoing open heart<br />
surgery between January 2011 and July 2011 who survived for at least 24<br />
hours postoperatively. Queensland health auslab defines the normal Bgl<br />
range as 3.0 -7.8 mmol/L. Results: Of the 166 patients in this study, 9.1%<br />
had type 2 diabetes at baseline. During hospitalisation, (median 10.9 days)<br />
8 of these patients suffered a non-fatal stroke, myocardial infarction, septic<br />
complication or died (termed “adverse outcomes”) 80.4% had optimal<br />
glycaemic control (Bgl 3.0-7.8 mmol/l) on the first post-operative day,<br />
and this decreased to only 65.8% at day 5 with optimal glycaemic control.<br />
The majority of our patients had bgL within tight limits, with the highest<br />
bgL in the cohort as 12.4mmol/L. There was no association between our<br />
patients outside of the bgL limits and adverse outcomes (P=NS). This<br />
was consistent with the findings of Estrada et al. who measured 30 day<br />
mortality, infection rates (sternum, harvest site, sepsis, pneumonia,<br />
urinary tract) and resource utilisation in a retrospective cohort of 1574<br />
patients and found no association between hyperglycaemia and mortality<br />
or infection rates, although their patients with hyperglycaemia experienced<br />
longer hospital stays. Conclusion: Although the perioperative glycaemic<br />
control in our cohort of patients was optimal, there remains opportunity for<br />
improvement. Hyperglycaemia is physiologically associated with oxidative<br />
stress in the myocardium, and hence the closure of any care gap leading to<br />
hyperglycaemia is imperative.<br />
A Longitudinal Study of the Career Paths of the First James Cook<br />
University Medical School graduates<br />
Aileen Traves¹ , ², Sarah Larkins², Tarun Sen gupta² and Richard Hays²<br />
¹Tropical Medical Training, Townsville<br />
²School of Medicine and Dentistry, James Cook University, Townsville<br />
Aim: to collect information regarding the career paths of the first graduates<br />
of the James cook university School of medicine during their first five<br />
postgraduate years, including where postgraduate employment and<br />
training has taken place, and what factors have influenced postgraduate<br />
employment and training. Methods: A longitudinal mixed methods study<br />
with data collection from the first cohort of graduates from the James<br />
Cook University School of Medicine (n=58). Following ethics approval,<br />
the quantitative data was collected via an online survey. A subgroup of<br />
participants was interviewed to explore their experiences in more depth,<br />
with a specific focus on those pursuing general practice careers. Survey<br />
data was collated and analysed using simple bivariate descriptive statistics.<br />
Interviews were transcribed in full and analysed with an iterative thematic<br />
analysis. Results: Many graduates have worked in rural, remote, Indigenous<br />
and tropical health related employment since graduation, with the majority<br />
remaining in Queensland. While only 10% of the cohort indicated an<br />
intention to work in general practice at the beginning of medical school,<br />
nearly 40% of the graduates have undertaken general practice training.<br />
there are many factors influencing career path decisions. more than<br />
80% of graduates intend to participate in teaching during their careers,<br />
and nearly 50% intend to participate in research. Conclusion: The focus<br />
S6 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM October 2011
on rural, remote, Indigenous and tropical health and strong promotion of<br />
general practice throughout the James Cook University medical course<br />
encouraged graduates to pursue careers in these fields.<br />
The Diabetic Host: Tropical Paradise for a Killer Bug<br />
Jodie Morris¹, Kelly Hodgson¹, Natasha Williams¹, Catherine Rush¹,<br />
Brenda govan¹, Kunwarjit Sangla², Robert Norton³ and Natkunam<br />
Ketheesan¹<br />
¹Microbiology and Immunology, James Cook University, Townsville<br />
²Department of Endocrinology, The Townsville Hospital, Townsville<br />
³Pathology Queensland, The Townsville Hospital, Townsville<br />
Aim: While there is increasing appreciation of immune dysfunction<br />
associated with type 2 diabetes (T2D), relatively few studies have<br />
investigated the implications of these alterations on subsequent hostpathogen<br />
interactions following infection. We developed a whole blood<br />
model of co-morbidity, together with an animal model to investigate early<br />
host-pathogen interactions that contribute to the increased susceptibility of<br />
individuals with T2D to gram negative infection. Methods: Peripheral blood<br />
from individuals with T2D, with poor or well-controlled glycaemia, and<br />
healthy non-diabetic (ND) individuals was stimulated with B. pseudomallei.<br />
Oxidative burst, expression of pathogen recognition receptors (TLR2,<br />
TLR4, CD14) and activation markers (CD11b, HLA-DR) were measured on<br />
neutrophils and monocytes. plasma inflammatory cytokine (il-6, il-12p70,<br />
TNF-α, MCP-1, IL-8, IL-1β, IL-10) concentrations were also determined. In<br />
parallel, we developed a diet-induced model of T2D to investigate disease<br />
progression following b. pseudomallei infection. Results: Differences were<br />
observed in expression of TLR2, CD14 and CD11b on phagocytes and in IL-<br />
12p70, MCP-1 and IL-8 plasma levels in blood from T2D and ND individuals<br />
in response to B. pseudomallei. Similarly, increased expression of TNF-α,<br />
IL-1 and IL-6 was observed following infection with b. pseudomallei in T2D<br />
mice, compared to nd mice. this paralleled extensive neutrophil infiltration<br />
and tissue damage at sites of infection in T2D mice and preceded mortality<br />
within the first few days following infection. Conclusion: Early interactions<br />
between B. pseudomallei and phagocytes are altered in hosts with T2D.<br />
These changes contribute to impaired leukocyte migration and activation,<br />
thus facilitating bacterial persistence and dissemination – a ticket to<br />
paradise!<br />
Bacteraemias in North Queensland: Trends, Susceptibilities and<br />
Outcomes<br />
Selina Porter¹, Natkunam Ketheesan¹ and Robert Norton²<br />
¹School of Medicine and Dentistry, James Cook University, Townsville<br />
²Pathology Queensland, The Townsville Hospital, Townsville<br />
Aim: to determine the source, significance, trends and antibiotic<br />
Make the move to<br />
Queensland Health<br />
Medical practitioners who possess medical registration with the<br />
Medical Board of Australia (MBA), or are otherwise eligible for<br />
registration with the Medical Board of Australia may apply through<br />
the RMO2012 Recruitment Campaign.<br />
For more information visit: http://www.health.qld.gov.au/rmo<br />
Volume 12 Supplement 1<br />
susceptibility patterns of bacteraemias seen in North Queensland over the<br />
period 2000-2009. Methods: Analysis of data prospectively collected in the<br />
Department of Microbiology, Townsville Hospital, relating to organisms<br />
from blood cultures. Results: A total of 64,126 blood cultures were<br />
collected over the period stated. Of these 8976 were positive and 61%<br />
(5524) of these were significant clinically. this was equivalent to 4407<br />
bacteraemic episodes (10.3/1000 admissions) Staphylococcus aureus,<br />
Coagulase negative Staphylococci and E.coli were the commonest isolates.<br />
There was a progressive increase in non multiresistant MRSA (nmMRSA)<br />
and group b streptococci with a decrease in Streptococcus pneumoniae.<br />
apart from a significant decrease in susceptibility of E.coli to gentamicin,<br />
there were no other significant trends in antimicrobial susceptibilities.<br />
Organisms unique to the region are Burkholderia pseudomallei, Brucella<br />
suis and group A streptococcus. Conclusion: To date this is the largest<br />
review of bacteraemias in australia and the first in this region. progressive<br />
increases in nmMRSA and gp b streptococci were noted. a significant<br />
decrease in S. pneumoniae is likely to be related to the introduction of<br />
immunisation. Regional differences in causative organisms of bacteraemia<br />
are also noted.<br />
Hospital Access Block – Exit Block Interaction<br />
Paul goldstraw, Desley Joyce, Yuwati Santoso and Cheryl White<br />
Gerontology Services, The Townsville Hospital, Townsville<br />
Introduction: Access block to TTH has focussed on beds and hospital<br />
admission processes. The exit process to the community services post<br />
hospital care has not been explored. Services are particularly required for<br />
older people. Aim: To review exit block, the provision of community support<br />
and to explore why people queue in hospital for home or nursing home<br />
(NH) care. Methods: Data was reviewed on patients waiting for nursing<br />
home placement (NHP), care decision making, Acute Care of the Elderly<br />
(ACE), readmission to ACE and availability of Aged Care Packages (ACP) in<br />
the community. Results: The NHP numbers peaked in 2009/10 at 29 and<br />
30 respectively. A NH discharge analysis showed 45% had not received any<br />
community support and carers stress occurred in 76% with rapid decision<br />
making in 70%. Subsequent to ACE, there has been a maximum reduction<br />
in the NH queue of up to 90%. ACE readmissions highlighted lack of family,<br />
lack of ACP availability and that a stressed carer was twice as likely to opt<br />
out of care. acp analysis 2010-2011 confirms significant delays at a cost<br />
of 4447 bed days. Conclusion: geriatric Medicine in the Acute Care setting<br />
reduces queuing for nh. lack of community services has significant<br />
impact on the carer and the demand for hospital beds. A paradigm shift<br />
in access concepts is required to include exit block focussing on subacute<br />
and community services.<br />
7 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
S7
POSTER ABSTRACTS<br />
The Townsville Hospital and James Cook University,<br />
School of Medicine and Dentistry Research Symposium<br />
Friday 14 October 2011 (12:30-4:00pm)<br />
Robert Douglas Auditorium, The Townsville Hospital<br />
Calciphylaxis at The Townsville Hospital: An Emerging Concept<br />
Usman Malabu¹, Darshan Shah², Valli Manickam², george Kan² and<br />
Kunwarjit Sangla¹<br />
¹Department of Endocrinology, The Townsville Hospital, Townsville<br />
²Department of Renal Medicine, The Townsville Hospital, Townsville<br />
Background: calciphylaxis is characterised by vascular calcification and<br />
painful skin necrosis with high mortality of up to 80% (1). With the use of<br />
multimodality and multidisciplinary care of the disease (2), it is not known<br />
whether the course and prognosis will improve. Objectives: The aim of<br />
the study was to review clinical cases and course of calciphylaxis at our<br />
hospital. Methods: All patients admitted to the Townsville Hospital from<br />
1 March 2006 to 28 February 2011 with diagnosis of calciphylaxis were<br />
studied. Results: Seven patients were reviewed comprising 5 females and<br />
2 males. All except one were Caucasians. Only one Australian aborigine<br />
was recorded. Aetiology of the ESRF was diabetes in 4 subjects while<br />
chronic glomerulonephritis and obstructive uropathy contributed one in<br />
each. only one patient confirmed to have calciphylaxis had normal renal<br />
function. All subjects received variable modalities of care including surgical<br />
wound debridement, sodium thiosulphate, cinacalcet, pamidronate<br />
infusion, hyperbaric oxygen and parathyroidectomy. Five of 7 patients<br />
representing 71% died. The causes of death: sepsis in 3 whose wounds<br />
failed to heal and acute myocardial infarction following completely healed<br />
skin lesions in the other 2. Of the 2 surviving subjects, a male still has<br />
partially healed ulcer on follow up as outpatient. The other, a female who<br />
presented with normal renal function responded well to pamidronate<br />
infusion. Conclusion: Calciphylaxis is not a rare syndrome at our centre,<br />
occurring predominantly in subjects with ESRF and Caucasians with poor<br />
outcome even after successful healing of the wounds. Deaths occurred<br />
principally from sepsis and myocardial infarction. Further prospective<br />
studies on a larger population are needed to verify our findings.<br />
Tele-oncology for Indigenous Patients: The Perspectives of Patients,<br />
Families and Health-workers<br />
Jennifer Mooi¹, Lisa Whop², Patricia Verery² and Sabe Sabesan¹ , ³<br />
¹Department of Medical Oncology, Townsville Cancer Centre, Townsville<br />
² Health Systems and Epidemiology Division, Cancer Epidemiology, Menzies School of<br />
Health Research, Darwin<br />
³School of Medicine, James Cook University, Townsville<br />
Aims: To describe the perspectives of Indigenous patients, their families<br />
and rural health-workers on video-consultation and this tele-oncology<br />
health service. Methods: Indigenous patients, their family members and<br />
health-workers who were involved in video-consultations were invited to<br />
participate in interviews using standardised questionnaires. These were<br />
conducted face-to-face, via telephone or video-conference. Responses<br />
from patients and families were recorded on a 5-point Likert Scale and<br />
grouped under 4 themes. Interviews with health-workers consisted of<br />
open-ended questions. Results: Of 23 Indigenous patients who had<br />
participated in video-consultations between 2007 and 2011, 13 had<br />
deceased at the time of this study, nine were interviewed and one could<br />
not be contacted. Two family members and six health-workers were also<br />
interviewed. Of the patients and family members interviewed, all (n=11,<br />
100%) were satisfied with the quality of video-consultation [first theme];<br />
able to establish satisfactory rapport with the specialist [second theme];<br />
and reported benefits of video-consultation over face-to-face consultation<br />
[third theme]. most (n=9, 82%) were highly satisfied with the care received<br />
via tele-oncology in partnership with their local health-workers [fourth<br />
theme]. Health-workers described overall positive experiences with videoconsultation<br />
and felt empowered to be actively involved in providing cancer<br />
care for Indigenous patients. All groups interviewed indicated an overall<br />
preference for video-consultation over face-to-face consultation - reasons<br />
quoted included reducing waiting time, cost, burden of travel and removal<br />
from local supports for Indigenous patients. Conclusion: This study<br />
suggests that tele-oncology is an acceptable model of care for Indigenous<br />
patients, allowing partnership with local health-workers to provide quality<br />
care for Indigenous cancer patients “at their door step”.<br />
The Relationship between Blood Pressure and Aortic Dilation in<br />
the Angiotensin II Mouse Model of AAA<br />
Tammy Dougan, Sai-Wang Seto, Corey Moran, Catherine Rush, Lynn<br />
Woodward and Jonathan golledge<br />
Vascular Biology Unit, James Cook University, Townsville<br />
Aim: Abdominal aortic aneurysm (AAA) is an abnormal ballooning of the<br />
body’s main artery. Sudden aneurysm rupture is responsible for ~1000<br />
deaths annually in Australia. The cause of AAA is poorly understood.<br />
Angiotensin II (AngII), a potent mediator of increased blood pressure<br />
(hypertension), contributes significantly to the development of vascular<br />
disease in humans; however experimental data supporting the involvement<br />
of angii-induced hypertension in aortic aneurysm remains conflicting.<br />
The aim of the present study was to assess effect of blood pressure<br />
on aneurysm formation in a mouse model of AAA. Methods: AAA was<br />
induced in mice genetically prone to vascular disease (apoE-/-; n=55) via<br />
subcutaneous infusion of angiotensin ii (angii; 1ug/kg/min) over 28 days.<br />
blood pressure (tail-cuff) and suprarenal aortic diameter (ultrasound) was<br />
determined at day 0 (baseline) then measured at 7-day intervals. Data were<br />
analysed using parametric or non-parametric tests in accordance with<br />
distribution of data, applying one-way analysis of variance (<strong>AN</strong>OVA) and<br />
Spearman r-squared test. p value less than 0.05 was considered significant.<br />
Results: Subcutaneous infusion of AngII over 28 days resulted in a timedependent<br />
increase in both mean blood pressure (MbP) and suprarenal<br />
aortic diameter (SRA). Mean maximum aortic diameter (MMD) and SRA<br />
diameter measured from harvested aortas was positively correlated<br />
with mean blood pressure measures at day 28 (r=0.3600; p=0.0111,<br />
r=0.3545; p=0.0079 respectively. Conclusion: AngII-induced hypertension<br />
contributes significantly to aaa formation in the apoE-/- mouse.<br />
Central Nervous System Tuberculosis: a Disease of Papua New<br />
guinea in North Queensland<br />
Pascallina Ting and Robert Norton<br />
Pathology Queensland, The Townsville Hospital, Townsville<br />
Objective: to describe cases of confirmed central nervous system (cnS)<br />
tuberculosis seen at the major tertiary referral centre of North Queensland<br />
over a 10 year period. To compare the demographics of this group with<br />
S8 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM October 2011
previously reported Australian cases. Design: A retrospective case series<br />
based study. Setting and participants: All cases of proven Mycobacterium<br />
tuberculosis infection of the central nervous system presenting to the major<br />
tertiary referral centre of North Queensland, between 2000 - 2010. Main<br />
outcome measures: Differences in demographics and incidence of cases<br />
in North Queensland compared with other published Australian studies.<br />
Results: 5 cases of confirmed cnS tuberculosis were identified over the<br />
10 year period with 2 deaths. All were from Papua New guinea with a<br />
mean age of 7 years. Imaging and early microbiological diagnosis was<br />
critical in making the diagnosis. HIV infection was not a contributing factor.<br />
multidrug resistance was inferred or confirmed in 2 cases. Conclusion:<br />
CNS tuberculosis is a disease being increasingly seen in North Queensland<br />
among children from Papua New guinea. Anticipation of multidrug<br />
resistance is important in the immediate management of suspected cases.<br />
This will have important socio-political implications.<br />
Position of Intramedullary Nail (Tri-gen and IMHS) Distal End in<br />
Relation to the Distal Anterior Cortex and Distal Femur for Proximal<br />
Third Femoral Fracture<br />
Wei-Yan Tan and Rhys Edwards<br />
Department of Orthopaedic Surgery, The Townsville Hospital, Townsville<br />
Aim: The nail was designed with a 2.0m AP bow to minimize anterior<br />
cortical impingement. This study was to determine the position of the most<br />
distal end of the Intramedullary Nail in relation to the anterior cortex and the<br />
blumensaat’s line. Methods: 64 post-operative lateral X-rays of proximal<br />
third femur fractures that were treated with the IMHS or Tri-gen Nail<br />
were identified. then the list of lateral femoral x-rays post intramedullary<br />
nails insertion were obtained. The distance from the anterior cortex was<br />
measured using the most distal screw insertion point as the reference<br />
point. Then from this reference point, the distance to the anterior cortex<br />
was measured using the measuring system on the Agfa Impax system.<br />
The distance of the distal nail to the distal end of the femur was measured<br />
using the tip of the IM nail to the blumensaat’s Line. Results: A frequency<br />
distribution of the distance from nail to cortex was constructed and it<br />
was found that in 27% of cases the nail was placed within 3mm of the<br />
anterior cortex. In 14% of cases, the nail was within the 1mm of the cortex.<br />
There was also a correlation between advanced age and anterior cortical<br />
impingement. Conclusion: There was a concerning number of patients<br />
whose distal end of the Tri-gen and IMHS nail was placed within the close<br />
proximity to the anterior cortex.<br />
Trends in Vitamin D levels in the Tropics<br />
Fiona B Millard¹ , ² and Jey Chinnathambi²<br />
¹Department of Psychiatry, School of Medicine and Dentistry, Townsville<br />
²Tropical Medical Training, Townsville<br />
Background: Vitamin D is produced by the skin in response to sunshine,<br />
and we may assume that people living in the tropics have adequate levels.<br />
This vitamin is important in keeping bones strong, supporting the immune<br />
system and protecting the brain and nervous system. Aim: To measure<br />
trends in vitamin D levels for people living in the tropics. Methods: Patients<br />
attending their general practitioner were invited to have a blood test to<br />
measure their vitamin D levels. Results were entered into SPSS software<br />
with cases identified by consecutive numbers and assigned variables of age,<br />
gender, date of test, vitamin D level, personal characteristics, occupation<br />
and medical history. Results: Results indicated that vitamin D levels vary<br />
with the seasons and weather patterns, with low levels more likely in spring<br />
and after a long wet season. vitamin d deficiency where levels were less<br />
than 50mmol/L was found in 20% of cases and low levels at 50-70mmol/L<br />
in 50% of cases. People of all ages can have low vitamin D levels, with a<br />
trend to low levels in those living or working indoors. Conclusion: Vitamin<br />
D levels can be low in people living in the tropics and the prevalence of low<br />
vitamin D levels suggests that testing should be encouraged in those at<br />
risk and measures taken to correct the problem, minimizing the risk of this<br />
deficiency contributing to future health problems.<br />
Volume 12 Supplement 1<br />
A Safety Survey of Nasogastric Feeding Tube Placement and Care<br />
at the Townsville Hospital<br />
Ching-Siang Cheng and Kristen Tuffin<br />
The Townsville Hospital, Townsville<br />
Aims: To determine the clinical practice at the Townsville Hospital with<br />
regard to Nasogastric Tube (Ng tube) placement and the nursing care of<br />
Ng tubes. Methods: this project was carried out in a two stages. the first<br />
stage involved a review of the existing guidelines and recommendations<br />
confirming ng tube placement and routine care afterwards. the second<br />
stage involved a questionnaire targeting the current cohort of interns, and<br />
random chart reviews in the month of July 2011 on ward patients with Ngtubes<br />
in position. Results: The National Patient Safety Agency (NPSA) of<br />
the uk recommended testing with ph indicator paper as the first line check,<br />
with checking x-ray images as the second line test. No evidence supported<br />
auscultation and bubbling to confirm correct ng tube placement. 43.5% of<br />
the interns surveyed (n=23) have not yet checked an Ng tube placement<br />
even after six months of internship. 39.1% checked placement about<br />
once a month, with the remainder performing checks more often. 91.3%<br />
stated a chest x-ray as the first-line for checking ng tube placement, while<br />
8.7% listed ph indicator paper as the first line check. none considered<br />
auscultation or bubbling as first line. Conclusion: Harm and even death<br />
can result from feeding into the lungs from misplaced Ng tubes. Due to the<br />
preventable nature of harm from misplaced Ng tubes, clinical audits such<br />
as this study can identify shortfalls and trend data to show improvement in<br />
clinical management of Ng tubes at the Townsville Hospital.<br />
Perinatal Arterial Ischemic Stroke in Northern Queensland<br />
Liza Edmonds¹, Yoga Kandasamy¹, Anthony LaMont² and Sara<br />
O’Connor¹<br />
¹Department of Neonatology, Women’s and Children’s Health Institute, The Townsville<br />
Hospital, Townsville,<br />
²Department of Radiology, The Townsville Hospital, Townsville<br />
Aims: Perinatal arterial ischemic stroke is a relatively rare event in<br />
the newborn period. Our aim was to review the occurrence of stroke,<br />
presentation and associated risk factors in infants admitted to our tertiary<br />
neonatal intensive care unit. Methods: infants were identified between<br />
March 2002 and March 2011 by searching the inpatient database. Maternal<br />
and neonatal hospital records were reviewed. All radiological imaging<br />
was reviewed by a paediatric radiologist to confirm presence of arterial<br />
stroke. Results: ten infants were identified as having had perinatal arterial<br />
ischemic stroke. Strokes were left sided in 4, right sided in 3, cerebellum<br />
in 1 and 2 were bilateral. Median birth weight was 2970g and median<br />
gestation at birth was 36 weeks. Overall mortality was 30% and indigenous<br />
infants made up 20% of the cohort. Pregnancy complications affected<br />
80% of the mothers and 60% of the cases had foetal distress present<br />
prior to delivery. Stroke presentations included 4 with seizures, 4 with<br />
apnoea/sepsis presentation, 1 with thrombosis elsewhere and 1 without<br />
symptoms. Retrieval was required for 5 of the infants. All infants had<br />
risk factors for stroke identified. Conclusion: Perinatal arterial ischemic<br />
stroke occurred within predominantly older gestation well grown infants<br />
in keeping with other studies. a significant number needed retrieval to a<br />
tertiary centre and the presentation features were variable. All infants had<br />
identifiable risk factors on history and investigation with a broad range of<br />
variables identified.<br />
Case Study: Syndrome of Hypertension and Hyperkalemia with<br />
Normal glomerular Filtration Rate<br />
Nadarajah Mugunthan and Kunwarjit Sangla<br />
Department of Endocrinology, The Townsville Hospital, Townsville<br />
Introduction: Monogenic hypertension syndromes have become the<br />
window to understand the new physiology of the nephron. All of these<br />
syndromes converge around a single mechanism: the regulation of<br />
9 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
S9
sodium ion transport within the distal nephron. Case Study: 26 year<br />
old female presented with episodes of headache for three months. She<br />
gave a history of hypertension from the age of 12 years which had been<br />
attributed for “white coat hypertension”. On examination her height was<br />
163cm with the weight of 72kgs. Her bP was 140-160/95-120. Her initial<br />
blood test revealed normal serum sodium level with serum potassium<br />
of 5.0-7.0mmol/l(N 3.5-5.1). Her serum bicarbonate level is 18mmol/l<br />
(N 20-28). Her Serum creatinine, blood urea and egFR and thyroid<br />
function tests were within normal range. Her renin level was low with<br />
normal aldosterone levels. her chest Xray was normal. a diagnosis of<br />
gordon Syndrome (Psudohypoaldosteronism type11) had been made<br />
and she was treated with thiazide diuretic bendroflurozide 5mg daily.<br />
Her symptoms, blood pressure and serum potassium normalized within<br />
days. later genetic testing in a research lab confirmed mutation in the<br />
family of serine-threonine kinases called With-No-lysine Kinases (WNK)<br />
genes. Discussion: this case highlights finding of abnormal potassium<br />
concentrations (low or high), alkalosis or acidosis, suppressed renin, and<br />
normal or low aldosterone should prompt the consideration of one of the<br />
rarer causes of hypertension. Further we discuss 1) Role of WNK kinases<br />
and their role in the pathogenesis of gordon syndrome 2) Potential newer<br />
therapeutic agents for hypertension to act on WNK kinases.<br />
The Utility of Cerebrospinal Fluid Protein in the Microbiological<br />
Assessment of Meningitis<br />
Kevin Ostrowski¹, Kyle White¹, Torres Woolley², Samuel Maloney¹ , ³<br />
and Robert Norton¹ , ³<br />
¹The Townsville Hospital, Townsville<br />
²School of Medicine and Dentistry, James Cook University, Townsville<br />
³Microbiology Unit, Pathology Queensland, Townsville<br />
Aim: the measurement of cerebrospinal fluid (cSF) protein is an essential<br />
part of the microbiological examination of cSF. the definitive aetiologic<br />
agent of meningitis is often not determined for some days after the lumbar<br />
puncture while the CSF protein is available in the initial assessment. The<br />
aim of this study was to look at the predictive value of the absolute CSF<br />
protein value in correlating with specific aetiologic agents. We also sought<br />
to find a relationship between cSF protein and cSF red cells and create<br />
a correction factor for traumatic lumbar punctures. Methods: This was a<br />
retrospective analysis of all CSFs taken at the Townsville Hospital during<br />
the study period of 1998 to 2010. Results: A total of 4354 CSFs were<br />
reviewed. Of these, there were 23 cases positive for bacterial meningitis<br />
(both Neisseria meningitides) which had a CSF protein (mg/L), mean<br />
and standard deviation, of 2028 (1744). 34 cases were positive for viral<br />
meningitis with protein of 578 (245). In patients with a CSF protein
The data suggests that there should be a low threshold for vitamin D essays<br />
in people over the age of 70 who present to the hospital in poor mobility.<br />
the data confirms that people who are housebound and living in nursing<br />
homes are a cohort that requires routine replacement.<br />
Splenic Varices: A Poorly Recognised Phenomenon<br />
Cassandra Faris¹, David Williams¹ and Enrico Roche²<br />
¹Department of Anatomical Pathology, The Townsville Hospital, Townsville<br />
²Department of Gastroenterology, The Townsville Hospital, Townsville<br />
Aim: The most important cause of portal hypertension is cirrhosis. The main<br />
consequences of portal hypertension are splenic congestion, including<br />
splenomegaly, with or without hypersplenism, and also porto-systemic<br />
shunting, anastomotic channels connecting the portal and systemic venous<br />
systems opening up and becoming distended. The more well known of<br />
such systems are the oesophageal tributaries of the azygous vein which<br />
connect through the diaphragm with the portal system. When varicose,<br />
these oesophageal tributaries are easily traumatised by the passage of<br />
food, the result being bleeding into the gastrointestinal tract. We aim to<br />
investigate the morbidity/mortality of splenic varices from a pathological<br />
and gastroenterology view point and would like to comment on how they<br />
may be treated clinically. Methods: Literature review, clinical perspective<br />
on management of splenic varices in cases of portal hypertension and<br />
case discussion including gross and microscopic findings of autopsy will<br />
be used. Results: Splenic varices of the hilar area have been described<br />
by radiologists in the literature, however, are not well known to morbid<br />
pathologists and not usually managed clinically by gastroenterologists in<br />
cases of portal hypertension secondary to cirrhosis. Conclusion: It appears<br />
that splenic varices is not a topic debated widely in the literature amongst<br />
gastroenterologists, morbid pathologists or radiologists given the low<br />
threshold for clinical intervention and is an area requiring further research<br />
given the cases which have been found of recent on autopsy secondary to<br />
splenic variceal haemorrhage.<br />
Researching the Use of Video Conferencing to Build Palliative<br />
Care Capacity in North Queensland<br />
Ofra Fried¹ and Robin Ray²<br />
¹Palliative Care Unit, The Townsville Hospital, Townsville<br />
²School of Medicine and Dentistry, James Cook University, Townsville<br />
Aim: Using video conferencing technology to provide educational<br />
opportunities for health and social care practitioners across north<br />
Queensland, this project aims to build palliative care capacity in rural and<br />
remote areas; enable palliative care patients to be more efficiently managed<br />
locally and remain among their support networks in their communities to<br />
the end of their life; evaluate the needs for palliative care education and<br />
the use of videoconferencing for more effectively meeting these needs.<br />
We will present the initial results of this project. Methods: A mixed<br />
method approach is being used to implement and evaluate the video<br />
conferences. Following an educational needs assessment, topics were<br />
prioritised. after the first four video conferences, participants completed<br />
an impact evaluation on-line survey including qualitative responses.<br />
Further evaluation is planned during the life of the two-year project.<br />
Results: The needs assessment reinforced the traditional palliative topics<br />
but also highlighted new areas of concern. Participation in each video<br />
conference averages 40 multidisciplinary practitioners from sites across<br />
north Queensland. The process of video conferencing was convenient<br />
for all especially for those in more remote areas and was rated as a very<br />
useful learning tool. program content rated highly with each specific<br />
topic meeting most participants learning and practice needs. Participants<br />
reported increased confidence across all four topic areas presented to date.<br />
Conclusion: Early results from this work in progress demonstrate a high<br />
level of interest in increasing palliative care knowledge. Video conferencing<br />
has proved a very useful tool for primary health providers across north<br />
Queensland to access palliative care education and improve practice.<br />
Volume 12 Supplement 1<br />
Meta-Analysis of Associations Between Transforming growth Factor<br />
Beta Polymorphisms and Coronary Heart Disease<br />
Dylan Morris, Joseph Moxon, Erik Biros and Jonathan golledge<br />
Vascular Biology Unit, James Cook University, Townsville<br />
Aims: The genetic risk factors for coronary heart disease (CHD) are<br />
incompletely understood. The aim of this study was to investigate the<br />
association between common single nucleotide polymorphisms (SNPs)<br />
in transforming growth factor (TgF)-β and CHD. Methods: We performed<br />
a systematic review and subsequent meta-analysis of studies published<br />
before 20th February 2011. Case-control studies assessing at least one<br />
TgF-β SNP in CHD patients were included in the meta-analysis. The random<br />
effects model was utilised to calculate odds ratios and confidence intervals<br />
for each TgF-β SNP. Results: Eight studies examining the association<br />
of TgF-β1 Snps with chd were identified. Six studies involving 5535<br />
cases and 2970 controls reported common SNPs and were included in a<br />
meta-analysis. Three SNPs in TgF-β1 were mildly associated with CHD:<br />
rs1800469 (OR=1.13, 95% CI 1.02-1.25, p=0.024), rs1982073 (OR=1.15,<br />
95% CI 1.03-1.28, p=0.016) and rs1800471 (OR=1.20, 95% CI 1.03-<br />
1.40, p=0.017). Conclusion: This meta-analysis suggests that genetic<br />
polymorphism in TgF-β1 influences the risk of developing chd.<br />
A Systematic Review of Barriers to Early Career Medical Research<br />
in the Australian Setting<br />
Harris Eyre and Michael Stuart<br />
School of Medicine and Dentistry, James Cook University, Townsville<br />
Aim: Recent reports have raised concerns of a decline in the supply of<br />
Australian clinician-scientists in the future. Involvement in undergraduate<br />
and early postgraduate research has been shown to enhance interest in<br />
this career path, and predicts a more successful academic career. There<br />
are many barriers to early career medical research in the current Australian<br />
setting including real, inbuilt issues in the delivery of medical training in<br />
the healthcare system and issues. Methods: The authors systematically<br />
reviewed national and international scientific literature and policies on the<br />
subject from the last 15 years. Results: Available evidence consistently<br />
demonstrates that medical students have significant interest in the<br />
clinician-scientist career path; however, they have a narrow understanding<br />
of what research entails. Interest has been reported to wane in the early<br />
postgraduate years owing to a lack of structured opportunities for research<br />
involvement, time factors, family and financial pressures. changes in the<br />
training environment as a result of increased medical student numbers<br />
may present several opportunities for enhancing the uptake of the clinicianscientist<br />
career path. Conclusion: At present, the absence of longitudinal<br />
studies limits our understanding of changing influences on the decision to<br />
pursue a research career and at what point this decision is made. Further<br />
studies of this type are required to better direct any programmes to boost<br />
uptake of this career path.<br />
How Do Contextual Issues Influence Social Accountability in Medical<br />
Education?<br />
Robyn Preston¹ , ³, Judy Taylor¹ , ², Sarah Larkins¹ and Jenni Judd³<br />
¹James Cook University, Townsville<br />
²Spencer Gulf Rural Health School, University of South Australia, Whyalla and University of<br />
Adelaide, Adelaide<br />
³Anton Breinl Centre, James Cook University, Townsville<br />
Aims: To investigate the progress towards socially accountable medical<br />
education in four medical schools in two countries. To analyse and<br />
compare key contextual factors that influence the planning, implementation<br />
and outcomes of socially accountable medical education within these<br />
sites. Methods: A cross-national multiple case study design using mixed<br />
methods: Background grey and peer reviewed literature; documents and<br />
archival records from Schools and other Institutions, semi-structured<br />
qualitative interviews; non-participant observation of a phenomenon at<br />
11 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
S11
each School. Results: From the literature, a working definition of ‘context’<br />
in my study will be conceptualised through bronfenbrennen’s ecological<br />
approach. Key contextual factors that will be initially investigated include:<br />
macro (historical context, policy environment, Fiscal environment);<br />
Meso (Health system, Reference Population / the community, Workforce<br />
issues); micro (leadership / governance, Student characteristics, Staff<br />
/ Faculty characteristics, Extracurricular activities). Conclusion: This<br />
research will demonstrate how progress towards social accountability<br />
in medical education can be evaluated in different socio-cultural and<br />
economic contexts; and give practical guidelines to medical schools, global<br />
organisations, non-government organisations and departments/ministries<br />
of health. Results may lead to the development of multi-site longitudinal<br />
studies to investigate the outcomes of socially accountable medical<br />
education in terms of graduate outcomes, cost effectiveness, quality and<br />
access to care and ultimately health outcomes. This project may also<br />
contribute the literature on case study methodologies in health services<br />
research, particularly methods to analyse context and contextual issues.<br />
The Implication for North Queensland Health Services of Aged<br />
Care Package Accessibility<br />
Robyn Russell, gillian Brunker, Margaret Boccalatte, Maria griffiths<br />
and Paul goldstraw<br />
Aged Care Assessment Services, Gerontology Services, The Townsville Hospital, Townsville<br />
Aim: Aged Care Packages (ACP) are designed to provide care to older<br />
people in the community. A recent study documented that 42% of older<br />
people waiting in hospital for a nursing home had not received community<br />
support. The accessibility to ACPs is unknown yet has individual and health<br />
service implications. This study was undertaken to determine if such<br />
delays existed and to what extent. Methods: When an ACP was approved,<br />
demographic, functional details and date of approval were recorded. The<br />
time taken to achieve access was determined by a weekly check with<br />
providers. The study period was 12 consecutive months. Results: A total<br />
of 285 ACPs were approved, of which only 12% (35) were accessed. Of<br />
those 35, 63% (22) already had lower level services in place, 23% (8)<br />
received less support than recommended. The waiting time ranged from 0<br />
to 190 days. During the year 180 (63%) of the cohort were admitted to TTH<br />
with 4447 bed days used, 23 (13%) died. Conclusion: The data suggests<br />
a significant delay in access and not necessarily to the recommended<br />
level. First time user access is poor with existing users having significantly<br />
greater access. Whilst other factors may influence the acp uptake, the<br />
mortality and morbidity of the cohort has implications for tertiary health<br />
services.<br />
Job Satisfaction among Rural and Remote general Practitioners:<br />
A Comparative Study Between Canadian and Australian Doctors<br />
Marco Viscomi<br />
School of Medicine and Dentistry, James Cook University, Townsville<br />
Background: Severe medical workforce shortages exist in both Australia<br />
and canada, especially in the field of rural general practice. despite the<br />
difficulty in recruiting and retaining doctors in these regions, there are<br />
many gPs who continue to practice in these underserviced areas. Aim:<br />
To determine what factors serve to attract and retain general practitioners<br />
in rural and remote areas of both Australia and Canada. This enables<br />
us to evaluate the efficacy of current undergraduate and postgraduate<br />
medical training programs and determine if these differences can be<br />
attributed to the employment of government policy initiatives. Methods:<br />
Internet and paper-based surveys will collect demographic information<br />
from all interested registered gP participants. A subset of participants will<br />
complete a semi-structured, telephone interview, with discussions focused<br />
around key general practice themes that aim to explore the strengths and<br />
weaknesses of rural practice and the impact these factors have on the<br />
doctor’s professional and personal life. Results: Preliminary survey results<br />
from Canadian and Australian gPs have demonstrated that the majority<br />
of rural gps are satisfied with their career choices, despite there being<br />
difficulties in obtaining adequate collegial support. many participants have<br />
indicated only partial satisfaction with family and personal life factors.<br />
Conclusion: Discussion focusing on the level of satisfaction among active<br />
rural gps can reveal the efficacy of current recruitment and retention<br />
strategies, whilst providing the opportunity to raise ideas that could allow<br />
improvements to be made in the future.<br />
An Insight Into the Impact of Pre-emptive Nursing Home Decision<br />
Making<br />
Cheryl White<br />
Gerontology Services, The Townsville Hospital, Townsville<br />
Introduction: A recent study at TTH showed that clinical and system<br />
processes of Nursing Home (NH) decision making for older people from<br />
the facility were often pre-emptive. Seventy percent of NH decisions<br />
were made on admission or within the first week. Aims: To increase<br />
the awareness of health decision makers, highlight unfortunate decision<br />
making with insights into the challenges faced when trying to reverse life<br />
changing decisions. Methods: The cases of 2 people admitted to residential<br />
aged care facilities (RACFs) from TTH who wished to reverse the decision<br />
were analysed in depth. Results: A 76 year old male was deferred from a<br />
previously recommended total knee replacement, due to his chronic leg<br />
ulceration with bacterial colonisation, was admitted to Interim, awaiting<br />
NH permanent placement. His house and contents were sold. Chronic<br />
wound management produced healing. He subsequently purchased a unit<br />
and was discharged. A 74 year old female placed in RACF from hospital<br />
as high level care, two months later is almost totally independent. She is<br />
currently negotiating her discharge and waiting for an aged care package.<br />
Conclusion: The timing of decision making was precipitant and affects the<br />
older person’s spiritual and psychosocial well being and thereby quality of<br />
life. The case reports demonstrate that reversing the decisions is possible<br />
but it is suggested that better access to gerontic subacute services and<br />
education would reduce life impact errors.<br />
S12 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM October 2011
DISCUSSION PAPER<br />
Improving Rural and Indigenous<br />
Cancer Outcomes: A Clinical Research<br />
Perspective<br />
Sabe Sabesan<br />
Director of Medical Oncology, Department of Medical Oncology, Townsville Cancer Centre,<br />
Townsville; and School of Medicine and Dentistry, James Cook University, Townsville<br />
Survival and quality of life among rural and indigenous patients after a cancer<br />
diagnosis are inferior to metropolitan figures. reasons for this disparity are<br />
many. 1 These include lack of access to health promotion services, primary<br />
health care and tertiary services, shortage of health work force and lack of access<br />
to cutting edge clinical trials to access new medical therapies; to name<br />
a few. Distance, isolation, indigenous status, and socioeconomic factors are<br />
additional correlates of poorer outcomes. Clinicians working with this disadvantaged<br />
group have the responsibility and opportunity to help close the gap<br />
by taking part in all three pillars of medicine; namely clinical medicine, clinical<br />
research and medical education. In this abstract, we illustrate how clinical<br />
departments might contribute to clinical research, using medical oncology<br />
as an example. While it is established that rural and indigenous cancer patients<br />
present with more advanced disease stages than their metropolitan<br />
counterparts, 2 there are few prospective studies on the reasons for this late<br />
stage presentation. The Townsville Cancer Centre (TCC) study on patterns of<br />
care in lung and head and neck cancers will hopefully shed more light on this<br />
issue in the near future.<br />
One arm of the TCC’s strategy has been to build its clinical trials capacity.<br />
Participation in clinical trials has become a standard of care for patients<br />
with metastatic cancers since patients in these trials have better outcomes. 3<br />
However, rates of participation are low among rural patients in Queensland<br />
(Personal communication: Ms Heather Day, Cancer Council Queensland) and<br />
centres with the capacity to conduct clinical trials are rare outside major cities.<br />
Starting from nothing 5 years ago, the TCC now employs 7 clinical trial<br />
nurses coordinating more than 35 multi centre trials between them. A survey<br />
to examine the knowledge and attitudes towards clinical trials reported rural<br />
patients were as willing to participate in clinical trials as their urban counterparts,<br />
but convenience of travel and cost were concerns. As a result, some<br />
trial budgets now have travel incentives at the TCC. 4 Under-treatment was<br />
thought to be a reason for disparity in outcomes and audits in lymphoma,<br />
colon cancer and breast cancers revealed that distance is not a contraindica-<br />
Volume 12 Supplement 1<br />
tion to intensive therapy. 5,6 These results are reassuring to the clinicians as<br />
they demonstrate that intensive therapy can be safely given to rural patients.<br />
Telemedicine has proven to be an effective tool for addressing access issues<br />
in several scenarios. It aids immediate access to specialist services<br />
and is particularly effective for indigenous communities. 7 The teleoncology<br />
network in Townsville and Mt Isa health services districts has transformed<br />
the rural cancer care in that all types of chemotherapy protocols are safely<br />
given in Mt Isa. Ward rounds of admitted patients and urgent review of sick<br />
patients have reduced the number of inter hospital transfers. This model of<br />
care is accepted by indigenous and non indigenous patients and welcomed<br />
by health workers, while maintaining cost effectiveness. 7,8 Using this model,<br />
plans are underway to administer simple chemotherapeutic protocols, supervised<br />
remotely by chemotherapy competent nurses from Townsville and<br />
Mt Isa, in all other smaller centres to foster the concept of telenursing. The<br />
flow on effect of improving access to mt isa is that we now have a comprehensive<br />
chemotherapy centre in Mt Isa which is fully resourced to deal with<br />
all types of chemotherapy protocols apart from high dose chemotherapy and<br />
transplant protocols.<br />
In conclusion, clinical research by clinicians has the potential to improve the<br />
quality of services to the rural and indigenous sectors and hopefully contribute<br />
to the “closing the gap” agenda.<br />
References<br />
Anton Breinl Centre for<br />
Public Health & Tropical Medicine<br />
1. Sabesan S, Piliouras P. Disparity in cancer survival between urban and rural patients: how can clinicians help<br />
reduce it? Rural and Remote Health 2009: No.1146. Available online at: http://www.rrh.org.au/articles/subviewnew.asp?articleid=1146<br />
(accessed: 13 September 2011)<br />
2. Australian Institute of Health and Welfare (AIHW) and Australasian Association of Cancer Registries: Cancer<br />
survival in Australia 1992-1997: geographic categories and socioeconomic status. Canberra: AIHW, 2003.<br />
3. Institute of Medicine Website. A National Cancer Clinical Trials System for the 21st Century: Reinvigorating<br />
the NCI Cooperative group Program. Available online at: http://www.iom.edu/Reports/2010/A-National-Cancer-<br />
Clinical-Trials-System-for-the-21st-Century-Reinvigorating-the-NCI-Cooperative.aspx (Accessed: 13 September<br />
2011)<br />
4. Sabesan S, burgher b, buettner P, et al. Attitudes, knowledge and barriers to participation in cancer clinical trials<br />
among rural and remote patients. Asia Pac J Clin Oncol 2011; 7: 27-33.<br />
5. burgher b, Sabesan S. Assessing the safety of adjuvant chemotherapy for high risk breast cancer and sarcomas<br />
among rural patients. Asia Pac J Clin Oncol 2009; 5 (Suppl. 2): a207.<br />
6. Scott AP, Sabesan S, Morris ES. Distance from treating center is not a risk factor for excess mortality or morbidity<br />
in patients receiving multiagent chemotherapy in North Queensland. Asia Pac J Clin Oncol 2009; 5 (Suppl.<br />
2): A165.<br />
7. Sabesan S, Simcox K, Marr I. Videoconferencing for medical oncology: acceptable model for patients and health<br />
workers. Int Med J 2011 (Accepted Article) Available online at: http://onlinelibrary.wiley.com/doi/10.1111/j.1445-<br />
5994.2011.02537.x/abstract (Accessed: 13 September 2011)<br />
8. Thaker D, Sabesan S. Cost effective analysis of videolinked medical oncology clinics: Townsville experience. Asia<br />
Pacific Journal of Clinical Oncology 2010; 6: 100-47.<br />
The Anton Breinl Centre for Public Health and Tropical Medicine seeks to undertake high quality and relevant teaching, research and<br />
training in population health, with a special focus on tropical Australia and our near neighbours.<br />
Postgraduate study programs:<br />
• Tropical Medicine • Public Health • Aeromedical Retrieval<br />
• Biosecurity and Disease Control • International Health • Refugee and Disaster Health<br />
• Rural, Remote and Indigenous Health<br />
For further information:<br />
• Travel Health and Diving Medicine<br />
Phone: +61 7 4781 6107 Email: sphtm-studentofficer@jcu.edu.au<br />
Visit: www.jcu.edu.au/phtmrs<br />
13 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
33898_JCU1033_MAKADS<br />
S13
Faculty of Medicine, Health and Molecular Sciences<br />
Cohort Doctoral Studies Program<br />
Focus your doctoral studies in a supportive environment<br />
with mentoring, peer support and professional<br />
development opportunities<br />
• For professionals working in areas of medicine, nursing, health (including rehabilitation and sport<br />
and exercise sciences), chemistry, and biomedical, molecular or veterinary sciences<br />
• Join as part of a cohort and progress with this group<br />
• Experienced academic mentor and peer support provided<br />
• Supportive and nurturing environment - workshops, seminars, coursework, peer learning facilitation<br />
and writing workshops<br />
• Block mode where students attend campus for a one-week period each semester<br />
• Electronic support for students outside of block teaching periods<br />
• Bridging program available for students without research experience or qualifications<br />
• Opportunities to undertake research related to your employment<br />
einl Centre for<br />
alth & Tropical Medicine<br />
r Public Health and Tropical Medicine seeks to undertake high quality and relevant teaching, research and<br />
lth, with a special focus on tropical Australia and our near neighbours.<br />
rams:<br />
Next program • Public commencing Health March 2012 with applications • Aeromedical due early January Retrieval 2012<br />
ontrol • International Health • Refugee and Disaster Health<br />
nous Health<br />
• Travel Health and Diving Medicine<br />
For further information, contact: Christine Teitzel.<br />
Email: christine.teitzel1@jcu.edu.au Phone: 07 4781 6964<br />
Fax: 07 4781 4901<br />
mail: sphtm-studentofficer@jcu.edu.au<br />
mrs<br />
S14 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM October 2011<br />
33898_JCU1033_MAKADS
MEMBERSHIP<br />
ACTM / FTM Membership Application<br />
Confidential<br />
Yes, I wish to join the ACTM / FTM as a: Fellow Member Associate Affiliate Corporate<br />
Title: Dr Prof Mr Mrs Ms Rev Col Capt Other<br />
Surname: Given names:<br />
Preferred name: Date of birth: Sex: Male Female<br />
Institution / Employer: Current position:<br />
Home address:<br />
City: State:<br />
Country:<br />
Work address:<br />
Postcode<br />
City: State:<br />
Country:<br />
Email<br />
Postcode:<br />
Work Phone: Home phone:<br />
Fax number:<br />
Academic Qualifications:<br />
Professional Qualifications:<br />
Previous Experience in Tropical Medicine:<br />
Preferred mailing address: Work Home<br />
Please note the Constitution and Code of Ethics on the College is available on the website: (www.tropmed.org/newactmconstitutionframe.htm)<br />
“I declare that I will uphold the Constitution and By-Laws of the College and its Faculties, adhere to the Code of Ethics of the College, and promote and respect the<br />
best interest of the College, its Faculties and its members.”<br />
Signature of Applicant: Date:<br />
Signature of Proposer1 :<br />
Name of Proposer in BLOCK letters:<br />
Date:<br />
Signature of Seconder1 :<br />
Name of Seconder in Block letters:<br />
Date:<br />
1. At least one of the nominator or seconder must be a Fellow of the College, otherwise please supply the names, address and telephone / fax numbers of two<br />
professional referees.<br />
Payment Options: Normal Annual Subscription/ Pro-rata Annual Subscription Life Membership<br />
Retired/ Subsidised/ Full time student membership (attach supporting letter from supervisor)<br />
Schedule of subscription rates $AUD (1 May 2011) Payment Method:<br />
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Associate<br />
$80 + $8 GST =<br />
$60 + $6 GST =<br />
$160 + $16 GST =<br />
$88<br />
$66<br />
$176<br />
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Money Order Enclosed (in Australian Dollars)<br />
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$200 + $20 GST =<br />
$60 + $6 GST =<br />
$176<br />
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Signature: Date:<br />
Please send:<br />
Full Curriculum Vitae and recent Passport-sized photograph<br />
List of publications, presentation and technical contributions (letter may also submit a teaching profile).<br />
Certified copies of degree / professional membership certificate<br />
Other supporting documents.<br />
Additional Opportunities I would like to find our more about:<br />
Membership Sponsorship Program - where members can sponsor the membership fee for qualified persons in developing countries.<br />
Voluntary Contributions - to support scholarships and other student projects.<br />
Return form to: ACTM Secretariat PO Box 123, Red Hill Qld 4059 AUST. P: +61 7 3872 2246 • F: +61 7 3856 4727 • E: actm@tropmed.org<br />
Do you know of any potential ACTM members? Please copy this application form as many times as you wish and pass them on.<br />
Volume 12 Supplement 1<br />
Sept2011 - 889<br />
15 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
S15
The Australasian College of Tropical Medicine<br />
Types of Membership<br />
The College has a range of membership options to suit<br />
professionals, students, organisations and companies, and<br />
other interested individuals.<br />
Fellow<br />
• Approved postgraduate academic qualification in tropical<br />
medicine or an approved fellowship in a related professional<br />
college or institute; <strong>AN</strong>D<br />
• Working, or have worked, a minimum of three years fulltime<br />
or the equivalent part-time in tropical medicine; <strong>AN</strong>D<br />
• Made a significant contribution to tropical medicine.<br />
Member<br />
• Approved postgraduate academic qualification in tropical<br />
medicine or an approved membership in a related<br />
professional college or institute and working, or have<br />
worked, a minimum of two years full-time or the equivalent<br />
part-time in tropical medicine; OR<br />
• Approved first degree and working, or have worked, a<br />
minimum two years full-time or the equivalent part-time in<br />
tropical medicine.<br />
Associate Member<br />
• Approved postgraduate academic qualifications in tropical<br />
medicine or an approved fellowship or membership in a<br />
related professional college or institute; OR<br />
• Approved first degree or approved certificate, assoicate<br />
diploma, diploma, or professional registration and working,<br />
or have worked, a minimum one year full-time or the<br />
equivalent part-time in tropical medicine<br />
Affiliate Member<br />
• Persons interested in tropical medicine.<br />
• Full-time students undertaking a course of study in tropical<br />
medicine or a related field at a recognised university or<br />
institute.<br />
Retired Member<br />
• Persons who have ceased full-time employment because of<br />
age or incapacity.<br />
Life Member<br />
• Fellow, Members, Associate Members and Affiliate Members<br />
who have paid the prescribed life membership fee. This may<br />
be paid for by installments, i.e. Pro-rata Life Membership.<br />
Corporate / Sustaining Member<br />
• Approved organisation or company. Annual membership<br />
only applicable.<br />
Purpose<br />
The Australasian College of Tropical Medicine Inc is the<br />
pre-eminent organisation in Australia and the region,<br />
representing professional interests in tropical medicine and<br />
promotes the highest ethical and professional standards<br />
through education and information. It has both regional<br />
and global interests with more than 400 members coming<br />
from over 30 countries around the world and maintains<br />
links to three international organisations working in<br />
tropical medicine. Membership includes medical doctors,<br />
scientists, academics, military personnel, consultants, and<br />
other health professionals. Several committees and subgroups<br />
within the College assist in organising local and<br />
regional scientific meetings, as well as other professional<br />
activities.<br />
Mission<br />
The College is committed to the development of tropical<br />
medicine and is working with professionals to help<br />
manage the global burden of tropical disease and injury<br />
through networking research and development.<br />
The aims of the college are to:<br />
• Encourage continuing education and the exchange of<br />
knowledge in tropical medicine;<br />
• Collaborate with other organisations in conducting<br />
activities of mutual concern, interest and direction in<br />
tropical medicine;<br />
• Promote research in tropical medicine;<br />
• Strive for professionalism and competence among its<br />
members and those specialising in and entering into<br />
the field of tropical medicine; and<br />
• Maintain in historical collection of items relevant to the<br />
development of tropical medical in Australia.<br />
History<br />
The Australasian College of Tropical Medicine Inc (ACTM)<br />
was founded at a meeting in Townsville, Australia on<br />
29 May 1991. Membership now extends to all states of<br />
Australia, and overseas. Membership includes many<br />
eminent professionals working in various fields relating<br />
to tropical medicine, such as parasitology, infectious<br />
diseases and tropical veterinary science, reflecting the<br />
broadest definition of tropical medicine. The College<br />
was incorporated in Queensland in 1994. The original<br />
secretariat was based at the Anton Breinl Centre, James<br />
Cook University - in the building used for the Australian<br />
Institute for Tropical Medicine established in 1910. A<br />
Faculty of Travel Medicine was launched in 2001. Further<br />
details on Faculty membership are available from the<br />
ACTM Secretariat.<br />
ACTM Secretariat PO Box 123, Red Hill Qld 4059 AUST. P: +61 7 3872 2246 • F: +61 7 3856 4727 • E: actm@tropmed.org<br />
S16 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM October 2011
<strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
<strong>AN</strong> <strong>INTERNATIONAL</strong> <strong>JOURNAL</strong> <strong>OF</strong> <strong>TROPICAL</strong> & <strong>TRAVEL</strong> <strong>MEDICINE</strong><br />
INSTRUCTIONS FOR AUTHORS<br />
The format of the Annals of the ACTM will, in general, follow guidelines of the “Uniform requirements for<br />
manuscripts submitted to biomedical journals” and published by the International Committee of Medical<br />
Journal Editors (http://www.icmje.org/index.html).<br />
The Annals will appear twice a year and will consider for publication, papers on a wide range of topics relating<br />
to tropical and travel medicine. All papers will be refereed prior to acceptance for publication. Papers<br />
will be included in one of the following categories:<br />
a) Review Articles (5,000-10,000 words)<br />
b) Research Articles (up to 5,000 words)<br />
c) Case Reports (1,000-2,000 words)<br />
d) Research Reports (1,000-2,000 words)<br />
e) Letters (200-500 words)<br />
Figures to be included: 1/4 page size = 250 words; 1/2 page size = 500 words etc. one page with images<br />
is approximately 900 words, two pages with image is approximately 1,800 words. Manuscripts should be<br />
double spaced and a short summary should be included at the beginning of the paper after the title and<br />
author details. Title page with contributor names and addresses should be on a separate page. Each table<br />
and figure should be on a separate page together with an appropriate caption, explanatory notes etc. any<br />
acknowledgements should be included at the end of the paper before the references. Where appropriate,<br />
authors must confirm in the paper that experimental procedures on humans and animals conformed to<br />
accepted international ethical guidelines. references should be numbered consecutively in order of first<br />
appearance in the text. For details of references, consult the “Uniform requirements for manuscripts submitted<br />
to biomedical journals” available at http://www.icmje.org/index.html.<br />
in the first instance, papers submitted for consideration should be sent to:<br />
The Editorial Board<br />
Annals of the Australasian College of Tropical Medicine<br />
ACTM Secretariat<br />
PO Box 123, Red Hill<br />
Queensland 4059 Australia<br />
Tel: + 61-7-3872-2246<br />
Fax: +61-7-3856-4727<br />
Email: actm@tropmed.org<br />
Statements or opinions in papers published in the Annals of the ACTM are solely those of the authors and<br />
not necessarily those of the Editorial board of The Australasian College of Tropical Medicine. The inclusion<br />
of commercial advertising material in the Annals or the College. The College disclaims any responsibility<br />
for any injury to persons or property resulting from publishing material or products referred to in articles<br />
or advertisements. On acceptance of an article for publication in the Annals, copyright of the article is<br />
automatically transferred to the ACTM.<br />
© Copyright 2011 ACTM<br />
Material published in the Annals of the ACTM is covered by copyright and all rights are reserved, excluding “fair use”, as<br />
permitted under copyright law. Permission to use any material published in the Annals of the ACTM should be obtained in<br />
writing from the authors and the Editorial board.<br />
Volume 12 Supplement 1<br />
17 <strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
S17 i
<strong>AN</strong>NALS <strong>OF</strong> THE ACTM<br />
<strong>AN</strong> <strong>INTERNATIONAL</strong> <strong>JOURNAL</strong> <strong>OF</strong> <strong>TROPICAL</strong> & <strong>TRAVEL</strong> <strong>MEDICINE</strong><br />
© Copyright 2011 The Australasian College of Tropical Medicine