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Wireless Connectivity for Medical Applications - Arrow Electronics

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<strong>Wireless</strong> <strong>Connectivity</strong> <strong>for</strong><br />

<strong>Medical</strong> <strong>Applications</strong>


<strong>Wireless</strong> <strong>Connectivity</strong> in Healthcare<br />

• <strong>Applications</strong> of <strong>Wireless</strong> <strong>Connectivity</strong> in Medicine<br />

– Remote monitoring of patients with implantable devices<br />

– Chronic disease management<br />

– Wellness and preventive medicine<br />

– Telemedicine<br />

• <strong>Wireless</strong> connectivity enables:<br />

– New ways to collect more data, more frequently, and cheaper<br />

– New ways to connect patients and health care professionals<br />

– New ways to manage health, disease, and life-style<br />

medicalsolutions@arrow.com<br />

2


Data Rate<br />

480 Mbps<br />

300 Mbps<br />

54 Mbps<br />

11 Mbps<br />

3 Mbps<br />

250 kbps<br />

20 kbps<br />

Passive RFID<br />

Potential <strong>Wireless</strong> Standards<br />

For <strong>Medical</strong> <strong>Applications</strong><br />

UWB<br />

IEEE 802.11n<br />

Bluetooth<br />

ULP<br />

Bluetooth<br />

IEEE 802.11a/g<br />

Active RFID<br />

IEEE 802.11b<br />

Zigbee<br />

1 10 100<br />

Range (meters)<br />

medicalsolutions@arrow.com<br />

• Passive RFID<br />

• Active RFID<br />

• Zigbee<br />

• Bluetooth Low Energy<br />

• Bluetooth<br />

• IEEE 802.11b<br />

• IEEE 802.11a<br />

• IEEE 802.11g<br />

• IEEE 802.11n<br />

•UWB<br />

..also GSM/GPRS<br />

3


Comparing <strong>Wireless</strong> Technologies<br />

• Key metrics:<br />

– Data rate<br />

– Range<br />

– Average and peak power consumption, battery life<br />

– Operating spectrum<br />

– Target packet error rate (PER) or bit error rate (BER)<br />

– Interference tolerance (co-existence)<br />

– Time to join the network<br />

– Network topology<br />

– Number of nodes that can be supported within topology<br />

– Memory requirements<br />

– Chip cost => and cost to use<br />

– Deployment volume and timing<br />

medicalsolutions@arrow.com<br />

4


Requirements of the <strong>Applications</strong><br />

• <strong>Applications</strong>:<br />

– Chronic disease management<br />

– Vital signs monitoring<br />

– Health & wellness<br />

– Connected diagnostic devices<br />

Biological Signal Data Rate (kbps)<br />

Blood pressure 0.01 - 10<br />

Pulse / Heart Rate 0.01-10 (40-200 Hz sample)<br />

Temperature 0.01- 10<br />

Respiration 0.01 -10 (10-80 Hz sample)<br />

Glucose 0.01 - 10<br />

SpO2 0.01 – 10<br />

EEG 10 - 200 (500Hz sample, 12-bit ADC, up to 32 channels)<br />

ECG 10 - 200 (500Hz sample, 12-bit ADC, up to 24 channels)<br />

EMG 10 - 500 (500Hz sample, 16-bit ADC, up to 32 channels)<br />

Still Images 1,000 - 2,000<br />

medicalsolutions@arrow.com<br />

5


Unlicensed and Dedicated <strong>Medical</strong> Spectrum<br />

174-216 MHz<br />

470-608 MHz<br />

614-668 MHz<br />

608-614 MHz<br />

1395-1400 MHz<br />

1427-1432 MHz<br />

402-405 MHz<br />

433.05-434.79 MHz<br />

868-870 MHz<br />

902-928 MHz<br />

2400-2483.5 MHz<br />

4940-4990 MHz<br />

5150-5350 MHz<br />

5470-5825 MHz<br />

Frequencies<br />

Available Bandwidth<br />

42 MHz<br />

138 MHz<br />

54 MHz<br />

6 MHz (1.5MHz/chan)<br />

5 MHz<br />

5 MHz<br />

3MHz<br />

1.74 MHz<br />

2 MHz<br />

26 MHz<br />

83.5 MHz<br />

50 MHz<br />

200 MHz<br />

355 MHz<br />

medicalsolutions@arrow.com<br />

<strong>Wireless</strong> medical telemetry at healthcare<br />

facilities – at risk <strong>for</strong> high levels of interference<br />

from DTV signals<br />

WMTS bands<br />

<strong>Medical</strong> Implant Communication Service (MICS)<br />

bands<br />

Europe unlicensed ISM3<br />

Europe unlicensed ISM<br />

US unlicensed ISM<br />

Unlicensed ISM<br />

Public Safety in US<br />

ISM unlicensed<br />

ISM unlicensed<br />

Description<br />

Note: Transmission power varies by country and frequency band. Access rules need to be followed<br />

6


Unlicensed and Dedicated <strong>Medical</strong> Spectrum<br />

202.65-205.15 MHz<br />

Frequencies<br />

420.05-430, 440-449.6625 MHz<br />

420.0625-430, 440-449.6375 MHz<br />

420.075-430, 440-449.6 MHz<br />

420.1-430, 440-449.525 MHz<br />

420.3-430, 440-449.425 MHz<br />

2.5 MHz<br />

Available Bandwidth<br />

Type A: 8.5 KHz<br />

Type B: 8.5kHz < BW < 16kHz<br />

Type C: 16kHz < BW < 32kHz<br />

Type D: 32kHz < BW < 64kHz<br />

Type E: 64kHz < BW < 320kHz<br />

medicalsolutions@arrow.com<br />

Description<br />

WMTS in New Zealand<br />

WMTS bands in Japan<br />

Note: Transmission power varies by country and frequency band. Access rules need to be followed<br />

7


Existing Dedicated <strong>Medical</strong> Spectrum<br />

EU<br />

USA<br />

Japan<br />

401402 403<br />

401 402 405 406<br />

401402<br />

401 402 405 406<br />

401<br />

Korea 401402<br />

402 405 420 429 440 449<br />

401 402 405 406<br />

MICS: Output power: 25μW ⇔ 9.1mV/m @ 3m, Signal BW = 300 KHz, Listen be<strong>for</strong>e talk (LBT)<br />

MICS Ext: (1) Transmit only: Output power: -36 dBm, Signal BW = 100 kHz, < 0.1% duty cycle;<br />

(2) Output power: -16 dBm, LBT with AFA<br />

US WMTS: 608-614 MHz, Output power: 200 mW/m, Signal BW = 1.5 MHz, only data, no voice or video<br />

US WMTS: 1395-1400, 1427-1429.5 MHz, Output power: 740 mW/m, only data, no voice or video<br />

Japan WMTS: 420-429 MHz, 440-449 MHz, Output power: 0.001 W <strong>for</strong> BW ≤ 64 kHz, 0.01W <strong>for</strong> BW > 64 kHz,<br />

Signal BW = 8.5, 16, 32, 64, 320 kHz, only simplex communication<br />

Taken from IEEE 802.15-07-0871-0ban: “Frequency Allocation Status of BAN” by Y. Yoon et al.<br />

medicalsolutions@arrow.com<br />

MICS MICS Ext WMTS<br />

608 614 1395 1400 1427 1429.5<br />

8


Standard<br />

Bluetooth<br />

Bluetooth Low<br />

Energy<br />

Zigbee /<br />

802.15.4<br />

Passive RFID<br />

Active RFID<br />

WLAN<br />

UWB<br />

Proprietary<br />

(Sensium)<br />

Comparison of <strong>Wireless</strong> Technologies<br />

Data<br />

Rate<br />

0.1-3<br />

Mbps<br />

1<br />

Mbps<br />

20-250<br />

kbps<br />

868<br />

kbps<br />

10’s of<br />

Mbps<br />

1-54<br />

Mbps<br />

53-480<br />

Mbps<br />

50 Kbps<br />

Range<br />

1-10 m<br />

(HPA: 100<br />

m)<br />

5-10 m<br />

1-100 m<br />

0.01-3 m<br />

0.01-100m<br />

10-100 m<br />

3-10 m<br />

~ 3m<br />

Join<br />

Time<br />

~3s<br />

1 year<br />

(depends<br />

on app)<br />

Memory<br />

Needed<br />

50-90 kB<br />

~50<br />

kB<br />

30-100<br />

kB<br />

< 100 B<br />

< 1 MB<br />

~0.5<br />

MB<br />

~250<br />

kB<br />

?<br />

Operating<br />

Spectrum<br />

2.4<br />

GHz<br />

2.4<br />

GHz<br />

868 MHz, 915<br />

MHz,<br />

2.4 GHz<br />

860 – 960<br />

MHz,<br />

13.5 MHz<br />

433 MHz<br />

2.4 GHz<br />

3.1 – 10.6 GHz<br />

862-870 MHz<br />

902-928 MHz<br />

9


Bluetooth / Bluetooth Low Energy


• Short-range wireless personal area network<br />

(WPAN) technology<br />

Overview of Bluetooth<br />

• Geared towards voice and data applications<br />

– Voice has guaranteed QoS – dedicated<br />

slots<br />

– Data supports both symmetric and<br />

asymmetric data rates<br />

• Operates in the unlicensed 2.4 GHz ISM<br />

band<br />

– Interference mitigated via adaptive<br />

frequency-hopping GMSK modulation<br />

scheme<br />

• Supported data rates: 100 kbps – 3 Mbps<br />

• Typical operating range: 1 – 10 meters<br />

(class 2 devices)<br />

• Master-slave topology; maximum of 8<br />

devices within a piconet<br />

• Standardization body: Bluetooth SIG<br />

medicalsolutions@arrow.com<br />

• Spectrum:<br />

– ISM band: starting at 2402 MHz<br />

– 79 channels spaced 1 MHz apart<br />

• Class 2 device: typical found in practice<br />

– Nominal: 0 dBm (1 mW)<br />

– Maximum: 4 dBm (2.5 mW)<br />

• Modulation:<br />

– Rates ≤ 1 Mbps: Gaussian FSK with BT = 0.5<br />

– Rates > 1 Mbps – 3 Mbps: π/4-DQPSK and<br />

8DPSK<br />

• Receiver sensitivity ≤ -70 dBm with a target<br />

BER = 0.1%<br />

• Frequency hopping:<br />

– Hopping sequence is based on a pseudorandom<br />

sequence<br />

– Rate: 1600 hops / sec<br />

– Normal mode: hop over 79 channels and<br />

master/slave channels are different<br />

– Adaptive frequency mode: hop over minimum<br />

of 15 channels and master/slave channels are<br />

the same<br />

11


Bluetooth Market Trends<br />

• Approximately 600Mu bluetooth-enabled handsets in 2008 growing to one<br />

Billion Bluetooth phones by 2011 reflecting more than 70% BT Attach-Rate<br />

(AR) in handsets<br />

– BT market is growing faster than the handset market<br />

• Notebook PC predicted to grow from 102 Mu in 2007 to ~230 Mu in 2012<br />

– Bluetooth penetration in notebooks predicted to rise from 43% in 2007 (~43Mu) to<br />

77% (~180Mu) in 2012<br />

• BT 2.1 is the latest approved spec, introducing simple secure pairing and sniffmode<br />

sub-rating<br />

• New Health Device Profile (HDP) approved and released in June 2008 by the<br />

<strong>Medical</strong> Technical Working Group (TWG)<br />

• BT SIG looking to go to higher data rates with WLAN or UWB PHY in BT 3.0<br />

medicalsolutions@arrow.com<br />

12


Bluetooth Low Energy<br />

(aka ULP & WiBree)


Overview Bluetooth Low Energy (aka ULP/ Wibree)<br />

• Now part of Bluetooth SIG, standardized as<br />

Ultra Low Power (ULP) Bluetooth<br />

– Designed <strong>for</strong> short bursts of traffic<br />

• Spectrum:<br />

– ISM band: starting at 2402 MHz<br />

– 39 channels spaced 2 MHz apart<br />

• Power: -20 to +10dBm power<br />

– Very Short distance communication<br />

– Range of about 10m with 0dBm TX<br />

power<br />

• Modulation:<br />

– Rates ≤ 1 Mbps: Gaussian FSK with<br />

BT = 0.5<br />

• No frequency hopping:<br />

– Uses fixed advertisement channels <strong>for</strong><br />

service discovery and pairing, data<br />

channels <strong>for</strong> communication<br />

• Sleep modes to conserve power<br />

• Allows <strong>for</strong> Scan only and broadcast only<br />

devices<br />

medicalsolutions@arrow.com<br />

• There are two types of devices:<br />

– Single mode – These only support<br />

ULP, and cannot communicate with<br />

regular BR/EDR Bluetooth devices<br />

– Dual mode – These devices support<br />

both ULP and BR/EDR Bluetooth<br />

devices, and can communicate with<br />

both (time-division multiplexing)<br />

• Peak current consumption low enough to<br />

enable use of primary lithium coin cells<br />

• Average power consumption low enough<br />

to enable operation <strong>for</strong> one year or more<br />

on primary batteries in many cases<br />

• Protocol optimized <strong>for</strong> low-duty cycle, low<br />

bandwidth communcation<br />

• Low complexity keeps RAM/ROM/CPU<br />

requirements low, enables low-cost<br />

devices<br />

• Very fast connection times enable both<br />

low latency and low power consumption<br />

• Good privacy and security<br />

14


BT Classic vs. BLE: PHY Layer Comparison<br />

BR/EDR BLE<br />

ISM bandwidth 2.400-2.4835 GHz 2.400-2.4835 GHz<br />

Frequencies<br />

Channel Spacing<br />

Data rate<br />

Range<br />

Modulation<br />

Mod. Index<br />

Maximum Power<br />

Sensitivity (BER=0.1%)<br />

f=2402+k MHz, k=0,…,78<br />

1MHz 2MHz<br />

1, 2 or 3 Mbps 1 Mbps<br />

5-10 m 5-10 m<br />

GFSK (BR), PSK (EDR) GFSK<br />

0.35 0.5<br />

+20 dbm (class 1) +10dbm<br />

Spec: -70 dbm<br />

BL6450: -92 dbm (BR), -86 dbm (EDR)<br />

Maximum Drift Rate 400 Hz/uS 400 Hz/uS<br />

Sync Word 64 bits 32 bits<br />

medicalsolutions@arrow.com<br />

f=2402+kx2 MHz, k=0,…,39<br />

Spec: -70 dbm<br />

BL6450: slightly better than -92 dbm<br />

Power Control YES NO (left <strong>for</strong> future spec release)<br />

15


Bluetooth Classic vs. BLE:<br />

Link Layer Comparison<br />

BR/EDR BLE<br />

Topology Star + Piconet Pure Star (no piconet)<br />

Roles<br />

Device Discovery<br />

Synchronous?<br />

MAC Addressing<br />

Packet Formats<br />

Error Protection<br />

Hopping Algorithm<br />

Data Packet Size<br />

Master, Slave, Role Switch Master or Slave. No Role Switch<br />

Master send page, Slave scan Master scans, slave advertises<br />

Fully Synchronous<br />

(625uS Slot-Pairs)<br />

48-bit IEEE Assigned<br />

Voice (SCO), Data (ACL) Data (ACL)<br />

Header – HEC. Data – FEC/CRC<br />

CRC is 16 bits<br />

Permutation based on butterflies<br />

medicalsolutions@arrow.com<br />

Semi-Asynchronous<br />

Scheduled connection events<br />

48-bit IEEE Assigned<br />

or Private Address (random, auth.)<br />

Header + Payload are protected by 24<br />

bit CRC<br />

pseudo-random modulo algorithm<br />

(X mod N)<br />

Maximum (ACL) 1021 bytes Maximum 31 bytes (27 in secured mode)<br />

Whitening YES YES<br />

Security Pseudo random XOR sequence AES-CCM (NIST approved)<br />

Packet Composing Flow Header: HEC->Whitening->FEC<br />

Payload: CRC->Encryption->Whitening->FEC<br />

Header and Payload: Encryption->CRC<br />

16


Legend<br />

Shipping/Sampling<br />

In design<br />

Under Study<br />

WLAN<br />

Roadmap<br />

(WiLINK)<br />

BT<br />

Roadmap<br />

ULP<br />

Roadmap<br />

802.15.4 /<br />

Zigbee<br />

Roadmap<br />

BSN<br />

Roadmap<br />

<strong>Wireless</strong> Portfolio & Roadmap<br />

Mass production<br />

6150<br />

BT 2.0<br />

130nm<br />

CC1101<br />


Bluetooth / BLE Roadmap<br />

BT6350<br />

BT ver 2.1<br />

WL1271/3<br />

BT ver 2.1 / BLE<br />

BT6450<br />

BT ver 2.1/<br />

BLE ready<br />

2008 2009 2010<br />

medicalsolutions@arrow.com<br />

CC2540<br />

ULP 1.0<br />

Compliant<br />

BT6460<br />

BT ver 2.1 /<br />

ULP Compliant<br />

ULP Only:<br />

8051 uC; 64KB/ 128 KB Flash<br />

ULP Compliance:<br />

0.9 revision spec – Nov 2008<br />

1.0 revision of of spec – Jun 2009<br />

18


CC2540 System-on-a-chip (SoC)<br />

USB_M<br />

1<br />

USB_P 2<br />

GND 3<br />

P1_7 4<br />

P1_6 5<br />

P1_5 6<br />

P1_4 7<br />

P1_3 8<br />

P1_2 9<br />

P1_1 10<br />

DVDD<br />

40<br />

12<br />

11<br />

P1_0<br />

DVDD<br />

P2_0<br />

P2_1<br />

39<br />

38<br />

CC2540<br />

P0_1<br />

P0_0<br />

37<br />

14<br />

13<br />

P2_2<br />

15<br />

P0_3<br />

P0_2<br />

P2_3<br />

36<br />

35<br />

17<br />

16<br />

DVDD<br />

P2_4<br />

DCOUPL<br />

34<br />

33<br />

18<br />

P0_5<br />

P0_4<br />

AVDD<br />

19<br />

P0_6<br />

AVDD<br />

32<br />

31<br />

20<br />

P0_7<br />

30 R_BIAS<br />

29 AVDD<br />

28 AVDD<br />

27 RF_N<br />

26 RF_P<br />

25 AVDD<br />

24 RESET_N<br />

23 XOSC_Q2<br />

22 XOSC_Q1<br />

21 AVDD<br />

• Single-cycle 8051 MCU with 64/128/256 kB insystem<br />

programmable Flash, 4 kB SRAM<br />

• Fully-integrated single-mode ULP Bluetooth<br />

radio<br />

• 21 configurable digital I/O pins with<br />

interrupt/wake-up<br />

• Digital peripherals<br />

– 2 USART (UART or SPI)<br />

– Full-speed (12 Mbps) USB 2.0 interface<br />

– 2x 16 bit, 2x 8-bit timers, dedicated Link Layer timer <strong>for</strong> ULP<br />

Bluetooth protocol timing<br />

– AES-128 encryption/decryption in HW<br />

• Advanced analog peripherals<br />

– 200 ksmpl/s 8-12 bit delta-sigma ADC<br />

– Ultra-low-power analog comparator<br />

– Integrated high-per<strong>for</strong>mance op-amp<br />


Zigbee / 802.15.4<br />

medicalsolutions@arrow.com<br />

20


What is ZigBee?<br />

• ZigBee is an open global standard <strong>for</strong><br />

wireless monitoring and control<br />

applications<br />

• ZigBee supports mesh networks which<br />

creates reliable and robust networks<br />

Why ZigBee?<br />

• The ZigBee alliance main focus is to<br />

standardize and enable interoperability<br />

of products within home, building and<br />

industrial automation.<br />

• Reliable wireless networks with low<br />

complexity and low cost<br />

• Various types of equipment from any<br />

number of vendors can be integrated<br />

• Require very little power (E.g. a light<br />

switch can run <strong>for</strong> years on inexpensive<br />

batteries)<br />

• Shorten development time by using a<br />

standardized and tested plat<strong>for</strong>m<br />

ZigBee<br />

medicalsolutions@arrow.com<br />

Zigbee Characteristics:<br />

� Very low duty cycle, very long primary<br />

battery life applications as well as<br />

mains-powered.<br />

� Static and dynamic mesh, cluster tree<br />

and star network structures with<br />

potentially a very large number of<br />

client units.<br />

� Low wake up and latency features.<br />

� Ability to remain quiescent <strong>for</strong> long<br />

periods of time without communicating<br />

to the network.<br />

� Data rates of 250 kb/s, 40 kb/s and 20<br />

kb/s.<br />

� Reliable and easy to configure and<br />

deploy.<br />

� Self Healing network.<br />

� Fully handshaked protocol <strong>for</strong> transfer<br />

reliability.<br />

21


Zigbee Networks<br />

� Three Device Types: Coordinator, Router and End Device.<br />

� Mesh Network support hundreds of nodes.<br />

� Network is Self Healing and easily configured.<br />

� Two addressing modes:: 16 bit short and 64 bit IEEE addressing.<br />

Point to Point Star Network Multihop – Mesh and cluster tree Networks<br />

ZigBee Coordinator<br />

ZigBee Router<br />

ZigBee End Device<br />

medicalsolutions@arrow.com<br />

22


Zigbee Frequency Bands and Data Rates<br />

BAND COVERAGE DATA RATE # OF CHANNEL(S)<br />

2.4 GHz ISM Worldwide 250 kbps 16<br />

868 MHz Europe 20 kbps 1<br />

915 MHz ISM Americas 40 kbps 10<br />

medicalsolutions@arrow.com<br />

23


IEEE 802.15.4 and ZigBee<br />

ZigBee v1.0 (Dec 04)<br />

ZigBee 2006 (Sept 06)<br />

ZigBee Pro (Q1 07)<br />

IEEE 802.15.4-2003<br />

superceded by<br />

IEEE 802.15.4-2006<br />

<strong>Applications</strong> User<br />

Application Profiles ZigBee or User<br />

Application Framework<br />

Network and Security<br />

Layers<br />

MAC Layer<br />

PHY Layer<br />

2.4GHz and 868/915 MHz<br />

medicalsolutions@arrow.com<br />

ZigBee<br />

IEEE 802.15.4<br />

Texas<br />

Instruments<br />

Silicon ZigBee Stack Application<br />

Khanh_01'0<br />

24


IEEE 802.15.4 2.4 GHz Silicon Per<strong>for</strong>mance<br />

Parameter<br />

Receive Sensitivity<br />

Output Power (Lowest maximum)<br />

RF Link Budget<br />

Adjacent Channel Rejection<br />

Alternate Channel Rejection<br />

Spec<br />

-85 dBm<br />

-3 dBm<br />

82 dB<br />

0 dB<br />

30 dB<br />

Texas Instruments the leading provider of IEEE 802.15.4<br />

medicalsolutions@arrow.com<br />

1st Gen<br />

-95 dBm<br />

0 dBm<br />

95 dB<br />

38 dB<br />

53<br />

2nd Gen<br />

-98<br />

+ 5 dBm<br />

103 dB<br />

49 dB<br />

54 dB<br />

25


CC2520<br />

2 nd Gen IEEE 802.15.4 2.4 GHz Radio Transceiver<br />

Features<br />

• Highly cost effective<br />

• -98dBm Sensitivity<br />

• +5dBm Output Power<br />

• >400m Line of Sight range<br />

• Extremely good selectivity<br />

– 50dB ACR<br />

– Robust radio<br />

• Extensive MAC support and AES-128<br />

• Direct downconversion/upconversion<br />

• 1.8 – 3.8 V , -40 to +125 ºC<br />

• 18.5 mA RX current<br />

• Small <strong>for</strong>m factor, QFN-28, 5x5mm<br />

SO<br />

SI<br />

CSn<br />

GPIO5<br />

GPIO4<br />

GPIO3<br />

GPIO2<br />

SPI<br />

Instruction<br />

decoder<br />

GPIO1<br />

SCLK<br />

Exception<br />

controller<br />

medicalsolutions@arrow.com<br />

IO<br />

GPIO0<br />

Bus controller<br />

XOSC32M_Q2<br />

DCOUPL<br />

XOSC<br />

Vreg<br />

Address<br />

filtering<br />

AES<br />

RAM<br />

BIST<br />

Atest<br />

XOSC32M_Q1<br />

VREG_EN<br />

DPU<br />

REF<br />

DIV<br />

AGC<br />

ADC<br />

AAF<br />

Clock/<br />

reset<br />

ADC<br />

RX MIX<br />

LNA<br />

RESETn<br />

FSM<br />

Demod<br />

ADI<br />

ADI<br />

PS<br />

FS<br />

Synthesizer<br />

Modulator<br />

DAC<br />

RBIAS<br />

Global<br />

bias<br />

RF_core<br />

LPF<br />

DAC<br />

TX MIX<br />

PA<br />

26<br />

RF_N<br />

RF_P


<strong>Wireless</strong> LAN


Overview of WLAN<br />

• <strong>Wireless</strong> local area network (WLAN) technology<br />

• Geared towards data-centric applications<br />

– Data-centric applications: web browsing, file transfers (mostly non-QOS<br />

apps)<br />

– IEEE 802.11e MAC extension to provide some level of QoS<br />

• Operates in the unlicensed 2.4 GHz ISM band<br />

– Interference mitigated via coding IEEE (802.11a/g/n), spreading (IEEE 802.11b)<br />

• Supported data rates:<br />

– IEEE 802.11b: 1 – 11 Mbps<br />

– IEEE 802.11a/g: 6 – 54 Mbps<br />

– IEEE 802.11n: 6 – 300+ Mbps<br />

• Typical operating range: 1 – 100 meters<br />

• Transmit power: IEEE 802.11b (17 dBm), IEEE 802.11a/g/n (13-15 dBm per<br />

antenna)<br />

• Infrastructure mode (255 devices), ad-hoc mode (point-point), mesh networking<br />

• Standardization body: IEEE and Wi-Fi Alliance<br />

medicalsolutions@arrow.com<br />

28


Overview of IEEE 802.11n<br />

• Extension of the IEEE 802.11a/g to multiple radios (both TX/RX) – MIMO<br />

technology<br />

• Spectrum: 2.4 GHz (mandatory) and 5 GHz (optional) ISM bands<br />

• Radios on transmitter:<br />

– 1 radio <strong>for</strong> single stream support (mostly <strong>for</strong> cell phones and portable<br />

devices)<br />

– Min. requirement: 2 radios <strong>for</strong> non-mobile device, could support up to 4<br />

radios<br />

• Channel BW: 20 and 40 MHz<br />

• Backwards compatible with IEEE 802.11a/g, but also has new Greenfield mode<br />

• Data rates: 6 – 300+ Mbps<br />

• Modulation scheme: MIMO-OFDM with 128-point FFT, 16, 32 sample CP, 4ms<br />

symbols<br />

medicalsolutions@arrow.com<br />

29


Proprietary Technologies<br />

medicalsolutions@arrow.com<br />

30


MICS<br />

medicalsolutions@arrow.com


• MICS (<strong>Medical</strong> Implant<br />

Communication Service)<br />

– 402–405 MHz<br />

– FCC established the band in<br />

1999<br />

– USA, EU, Australia, New<br />

Zealand, Japan and Canada<br />

harmonization<br />

• Although recently some<br />

proposals to ETSI to<br />

deregulate MICS band<br />

– Other countries expected to<br />

follow<br />

– Frequency band shared with<br />

meteorological aids (weather<br />

balloons)<br />

• MICS considered a<br />

“secondary” allocation of the<br />

frequency spectrum<br />

MICS Standard<br />

Channel 1<br />

402 MHz<br />

medicalsolutions@arrow.com<br />

Features<br />

Short range telemetry ~2 m<br />

Power limited to 25 mW EIRP<br />

(outside the body)<br />

300kHz bandwidth<br />

Allows up to 10 “channels”<br />

Channel 2<br />

Channel 3<br />

Channel 4<br />

Channel 5<br />

Channel 6<br />

Channel 7<br />

300 kHz<br />

Channel 8<br />

Channel 9<br />

Channel 10<br />

405 MHz<br />

25 μW (-16 dBm)<br />

32


<strong>Wireless</strong> <strong>Connectivity</strong> Cardiac Health Management<br />

LPW ??<br />

MICS LP RF<br />

medicalsolutions@arrow.com<br />

GSM / GPRS<br />

BT / BLE<br />

or LPW<br />

BT / BLE<br />

or LPW<br />

33


TI MICS Solution Proposal (strawman)<br />

• Frequency range : 401-406Mhz (MICS and MEDS)<br />

• Data rate : 200-800kbps and lower<br />

• Output power : +3 dBm (max)<br />

• TX current : < 5 mA (max)<br />

• RX current : < 5 mA (max)<br />

• Power Supply Rail: 1.5 V<br />

medicalsolutions@arrow.com<br />

34


Proprietary Low Power <strong>Wireless</strong><br />

SoCs: Sensium<br />

medicalsolutions@arrow.com


WMTS / WLAN<br />

Patient Worn Monitors to<br />

Wearable wireless patches<br />

Vital Signs Monitoring:<br />

•Heart rate<br />

•ECG (3- 6 leads)<br />

•Respiration<br />

•Temperature<br />

•SpO2<br />

•Blood pressure<br />

•2-5 days portable operation (AA or AAA batteries)<br />

•Patient data viewable from central monitoring station<br />

•Patient able to roam throughout hospital while<br />

connected<br />

Enables small, flexible, disposable wireless sensor patches:<br />

•Operate from button-cell or flexible batteries (printable or thin-film Li-ion)<br />

•Consume low enough power <strong>for</strong> 5 day (ECG) � 1 year (temp sense) operation<br />

•Low cost implementation<br />

medicalsolutions@arrow.com<br />

36


Sensor Interface<br />

AMPERO_P<br />

MEASUREMENT<br />

10 samples @100sps<br />

t so<br />

AMPERO_N<br />

MEASUREMENT<br />

10 samples @100sps<br />

t so<br />

THERMAL<br />

MEASUREMENT<br />

10 samples @100sps<br />

tso – switch-over time (programmed by MAC


Battery Comparison<br />

Flexible<br />

Thin<br />

Zinc Air<br />

Button<br />

Lithium<br />

Coin<br />

medicalsolutions@arrow.com<br />

AAA/AA Rechargeable Li-<br />

Ion/Polymer<br />

Voltage (V) 1.0~1.5 1.0~1.5 ~ 3.0 1.5 ~ 3.6<br />

Maximum<br />

Current (mA)<br />

Typical Charge<br />

(mAh)<br />

Easily<br />

Disposable<br />

< 3 < 10 > 15 > 100 > 1000<br />

30 150 220 1000 1000<br />

Increasing Power<br />

✘ ✘ ✘<br />

38


<strong>Wireless</strong> <strong>Connectivity</strong> Product Portfolio<br />

Peak I (mA)<br />

> 50<br />

25 – 50<br />

10 – 25<br />

0 – 10<br />

SG1<br />

Sensium 1<br />

SOC<br />

Proprietary<br />

130nm<br />

0 – 250K<br />

CC2431<br />

802.15.4<br />

+Zigbee<br />

+Location<br />

180nm<br />

CC2530<br />

802.15.4<br />

+Zigbee<br />

SOC<br />

180nm<br />

SG2<br />

Sensium 2<br />

SOC<br />

Proprietary<br />

130nm<br />

Data Rate vs. Peak Current<br />

MICS<br />

Proprietary<br />

130nm<br />

CC1111<br />

10M<br />

WL1251<br />

802.11 bg<br />

90nm<br />

WL1271<br />

802.11 abgn<br />

BT 2.1+EDR<br />

Wibree/ULP<br />

65nm<br />

39


Body Area Network <strong>for</strong><br />

Vital Sign Monitoring<br />

medicalsolutions@arrow.com<br />

40


Body Area Networks<br />

• Network that operates in, on, around the body<br />

• Limited range


<strong>Wireless</strong> <strong>Connectivity</strong> Solutions: Example BAN<br />

Pulse<br />

Temp.<br />

Blood press.<br />

BT / ZigBee /<br />

BLE /<br />

proprietary<br />

BAN hub<br />

WLAN / BT /<br />

/BLE/ ZigBee /<br />

proprietary<br />

medicalsolutions@arrow.com<br />

GSM / GPRS / 3G<br />

BT / ZigBee /<br />

proprietary<br />

= TI coverage<br />

42


Challenges with <strong>Wireless</strong> VSM / BASN<br />

• Open vs. Proprietary standards/protocol:<br />

– Open: Bluetooth/ULP, Zigbee<br />

– Proprietary: 802.15.4 (custom stack), Sensium NSP<br />

• Multiple frequency options:<br />

– 2.4 GHz<br />

– 800/900 MHz (ISM)<br />

– 400 MHz (MICS/MEDS)<br />

• Security/authentication/pairing:<br />

– Interference from other RF devices (2.4 GHz)<br />

– Co-existence in the presence of nearby BANs<br />

– Patient to hub/monitor pairing<br />

• Battery Life and <strong>for</strong>m-factor<br />

• Provide location in<strong>for</strong>mation<br />

• Integration with Essential Sensor technology:<br />

– NIBP, respiration<br />

medicalsolutions@arrow.com<br />

43


<strong>Wireless</strong> <strong>Connectivity</strong> <strong>for</strong><br />

Health & Wellness<br />

OMAP <br />

LoCosto <br />

2.4GHz ISM<br />

(Zigbee/BT/<br />

802.15.4/BLE)<br />

Bluetooth /<br />

BLE<br />

GSM/GPRS<br />

Zigbee /<br />

802.15.4<br />

800 MHz /<br />

900 MHz ISM<br />

Bluetooth /<br />

BLE<br />

medicalsolutions@arrow.com<br />

Weight Management<br />

Chronic Disease<br />

Management<br />

Vital Signs Monitoring<br />

Blood<br />

pressure<br />

monitor<br />

Smart<br />

bandage<br />

Weight<br />

scale<br />

44


Connected Diagnostic Devices<br />

BT<br />

WMTS / WLAN<br />

medicalsolutions@arrow.com<br />

BT / WLAN<br />

BT / WLAN<br />

45


Standards <strong>for</strong> Telemedicine and<br />

Remote Monitoring<br />

• ISO / IEEE 11073:<br />

– Point-of-care medical device communication standards: “Building the Foundation <strong>for</strong> <strong>Medical</strong> Device Plug-and-<br />

Play Interoperability<br />

– http://www.ieee1073.org/overview/overview.html<br />

• HL7 (Health Level 7):<br />

– HL7 is an international community of healthcare subject matter experts and in<strong>for</strong>mation scientists<br />

collaborating to create standards <strong>for</strong> the exchange, management and integration of electronic healthcare<br />

in<strong>for</strong>mation. HL7 promotes the use of such standards within and among healthcare organizations to increase<br />

the effectiveness and efficiency of healthcare delivery <strong>for</strong> the benefit of all.<br />

– Is an ANSI standards development organization (SDO)<br />

– https://www.hl7.org/<br />

• Continua Health Alliance:<br />

– “Our Mission is to establish an eco-system of interoperable personal health systems that empower people &<br />

organizations to better manage their health and wellness”<br />

– Health & Wellness, Disease Management, Aging Independently<br />

– http://www.continuaalliance.org/home<br />

• IEEE BAN ( 802.15.6 Working group): “This is a standard <strong>for</strong> short range, wireless communication in the vicinity of,<br />

or inside, a human body (but not limited to humans). It can use existing ISM bands as well as frequency bands<br />

approved by national medical and/or regulatory authorities. Support <strong>for</strong> Quality of Service (QoS), extremely low<br />

power, and data rates up to 10 Mbps is required while simultaneously complying with strict non-interference<br />

guidelines where needed.”<br />

– IEEE 802.15.6 – Formed in November 2007<br />

– Call <strong>for</strong> applications: due March 2008<br />

– Initial Sponsor Ballot submission: November 2009<br />

– Submission to RevCom: March 2010<br />

medicalsolutions@arrow.com<br />

46


Contact In<strong>for</strong>mation<br />

To learn more about technology solutions <strong>for</strong><br />

medical applications from <strong>Arrow</strong>, Texas<br />

Instruments, contact the <strong>Arrow</strong> <strong>Electronics</strong><br />

<strong>Medical</strong> Group at 866-260-1401, or email<br />

medicalsolutions@arrow.com.

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