OptiBond™ XTR - kerr thailand

OptiBond XTR
Self-Etch Universal Adhesive

Adhesive System Shortcomings
Material incompatibilities
with self/dual cure materials
Post-Operative
Sensitivity
Excessive film thickness
Inadequate etching &
adhesion of SE adhesives

Dentin
Open dentinal
tubules
Post-Operative Sensitivity
Pulpal floor
Leading to nerve
endings

Inadequate Etching/Adhesion to
Enamel of Self-Etch Adhesives
ClearFil SE Xeno IV
SEM images magnified at 50,000X
• Reduces bond strength to enamel
• Perform selective etching along the margin
• Increases technique variability
• Run the risk of causing sensitivity

SEM images magnified at 2,000X
Excessive Film thickness
~35μm
• Film thickness of an adhesive
determines how well a precision
restoration will fit
• Adhesives with low film thickness
allows for a very tight fitting indirect
restoration to seat completely
• Adhesives with high film thickness
may not seat completely, resulting
in excessive margin width and the
occlusion out of alignment

Cement Layer
3° amine (base)
H + (acid)
Adhesive Layer
Material Incompatibilities
Acidic adhesive
layer neutralizes
basic catalyst
components of the
cements
• Simplified bonding agents combining
primer and adhesive (5 th and 7 th
generation) contain acidic monomers.
• After light curing, uncured acidic
monomers from the oxygen-inhibited layer
of the cured bonding agent are in direct
contact with the resin composite/cement.
• These acidic monomers react (neutralizing
effect) with the basic catalyst components
of the chemically- or dual-cured
composites/cements, hindering the curing
of composite/cement at the bonding
interface

OptiBond XTR – Product Description
• OptiBond XTR is a self-etch 2-component, light cured, 15% filled
(including nano fillers), fluoride releasing bonding agent.
• Indicated for direct and indirect restorative procedures
• Separate hydrophilic self-etching primer with enhanced etching
capabilities
• Separate hydrophobic adhesive to maximize material compatibility,
increase strength and promote bond durability

OptiBond XTR – Product Goals
• Provide more robust self-etching/bonding to un-cut enamel and all other
dental substrates
• Improve bond strengths to enamel and dentin vs. current self-etch adhesives
• Provide improved durability and marginal integrity
• Lower film thickness
• Enhance bond compatibility with self-cured composites/resin cements
• Develop a bonding agent with universal application
• Minimize post-operative sensitivity

Solvent Role
Ternary Solvent System
Water • Provides medium for acid monomer to manifest its
acidity necessary for effective enamel etch
• Enhances wetting ability of primer to facilitate
etching and penetration
Acetone • Rapid evaporation of acetone increases
concentration of water and acidic monomer and
decreases pH to enhance primer etching
Ethyl
Alcohol
Mechanism of Action of OptiBond XTR Self-
Etching Primer
• Enhances wetting ability of the primer to facilitate
penetration of primer
• Acts as a compatibility vehicle between the more
hydrophobic monomer and water, preventing phase
separation (or bubble/void formation) and
maintains a homogenous primer layer as solvents
are removed during air-drying
Hydrophilic nature/enhanced
wetting of primer allows for
enhanced penetration into dentin
Promotes effective
penetration, priming, and
sealing of dentin
Application of Primer
to enamel or dentin
Acetone rapidly evaporates,
concentrating GPDM/water and
increasing acidity and thus
etching
Promotes effective etching of
enamel

• GPDM adhesive monomer
Primer Chemistry
OptiBond XTR ClearFil SE Bond
Phosphate functional group for etching & adhesive properties
O
O
OH
O P OH
O
Methacrylate groups for copolymerization & cross-linking
• Solvent: Water/Ethanol/Acetone
• Hydrophilic co-monomers
• Camphorquinone and stabilizer
pH = 2.4
O
O
pH = 1.6
• MDP adhesive monomer
CH 3
CH 2
C
C
O
O
• Solvent: Water
• Hydrophilic co-monomers (HEMA)
• Camphorquinone
• N,N-Diethanol-p-toluidine
pH = 2.5
O
OH
P
O
OH

• Hydrophobic monomer
• Structural monomer
• Crosslinking monomer
• Camphorquinone
• Stabilizer
• Solvent: Ethanol
• Reinforcing fillers – 15%
Adhesive Chemistry
OptiBond XTR ClearFil SE Bond
• 0.4-micron barium glass
• Nano-silica
• Fluoride releasing filler
• MDP
• Bis-GMA
• 2-Hydroxyethyl methacrylate
(HEMA)
• Hydrophobic dimethacrylate
• dl-Camphorquinone
• N,N-Diethanol-p-toluidine
• Silanated colloidal silica – 7%

OptiBond XTR Comparative Self-
Etching Capability on Uncut Enamel
OptiBond XTR and ClearFil SE etching efficacy on uncut enamel
OptiBond XTR ClearFil SE
SEM images magnified at 50,000X

Monomer Penetration
Excellent monomer penetration into dentinal tubules, shown as well defined
resin tags exhibiting rough surface along with lateral branches, was achieved.
SEM images magnified at 2,000X and 10,000X
OptiBond XTR

OptiBond XTR Film Thickness
Comparison
OptiBond XTR and ClearFil SE Comparison of Film Thickness
OptiBond XTR (~5 microns) ClearFil SE (~35 microns)
SEM images magnified at 2,000X
~5μm
~35μm

Comparative Shear Bond Strength to
Dentin
OptiBond XTR Comparative Dentin Bond Strengths vs. Leading Adhesives
OptiBond XTR
ClearFil SE
Xeno® IV
iBond®
OptiBond FL
0 5 10 15 20 25 30 35 40 45
Shear Bond Strength (MPa)
• OptiBond XTR demonstrated comparable
dentin bond strengths to Xeno IV
• OptiBond XTR demonstrated higher
dentin bond strengths than total-etch
and other self-etch adhesives
Data on File
Kerr Corporation

Comparative Shear Bond Strength to
Uncut Enamel
OptiBond XTR Comparative Enamel Bond Strengths vs. Leading Adhesives
OptiBond XTR
ClearFil SE
Xeno IV
iBond
OptiBond FL
0 5 10 15 20 25 30 35
Shear Bond Strength (MPa)
• OptiBond XTR demonstrated comparable
bond strengths to OptiBond FL (a totaletch
adhesive system) on uncut enamel
• OptiBond XTR demonstrated higher
enamel bond strengths than all self-etch
adhesives tested
Data on File
Kerr Corporation

Shear Bond Strength (MPa)
Independent Testing of OptiBond XTR
OptiBond XTR Bond Strengths to Dentin and Enamel at three Independent Sites
60
50
40
30
20
10
0
56.9
38.7
43.3 41
47.4
38.7
SUNY UNC Dental Advisor
Dentin Cut Enamel
• OptiBond XTR demonstrated consistently
high enamel and dentin shear bond
strength when tested at three
independent testing sites
• Shows a high rate of reproducibility and
predictability
Data on File,
Kerr Corporation

Shear Bond Strength (MPa)
60
50
40
30
20
10
0
Independent Testing - Dental Biomaterials
Research, State University of New York,
Buffalo
OptiBond XTR Comparative Bond Strengths to Dentin and Enamel
a
56.9
A
38.7
49.5
27
*Shear bond strength values obtained for samples bonded to human dentin and cut human enamel.
Same letter tags above the group indicate no significant differences found between groups
35
24.5 36.4 25.8
OptiBond XTR OptiBond FL Xeno IV ClearFil SE Bond
OptiBond XTR
a,b
B
b,c
Dentin Cut Enamel
B
c
B
• OptiBond XTR demonstrated comparable
bond strengths to dentin as OptiBond FL
• OptiBond XTR demonstrated statistically
superior bond strengths to dentin vs.
Xeno IV and ClearFil SE Bond
• OptiBond XTR demonstrated statistically
superior bond strength to enamel vs.
OptiBond FL, Xeno IV, and ClearFil SE
Bond
State University of New York, Buffalo
Dr. Carlos Munoz

Shear Bond Strength (MPa)
45
40
35
30
25
20
15
10
5
0
40.4
Independent Testing – Department of Operative
Dentistry, University of North Carolina
OptiBond XTR Comparative Bond Strengths to Enamel
41
32
18.1
OptiBond OptiBond XTR
XTR OptiBond FL ClearFil SE Bond Xeno IV
Cut Enamel
*Shear bond strength values obtained for samples bonded to bovine cut enamel.
• OptiBond XTR demonstrated comparable
bond strengths on enamel as OptiBond
FL
• OptiBond XTR demonstrated higher
enamel bond strengths vs. ClearFil SE
and Xeno IV
University of North Carolina
Dr. Edward Swift

Shear Bond Strength (MPa)
45
40
35
30
25
20
15
10
5
0
Comparative Indirect Shear Bond Strength
Using Self-Cured Resin Cements
OptiBond XTR Comparative Dentin Bond Strengths with Resin Cements
in Self-Cure Mode vs. 7 th generation Adhesives
G-Bond I-Bond Clearfil S3 Bond OptiBond XTR
Calibra Variolink II NX3
*Indirect Dentin Bond Strength of 7th Gen Adhesives (with Self-Cured Calibra, Variolink, and NX3 Resin Cement). All bonding
Agents were light-cured. Cements were allowed to self-cure
• OptiBond XTR exhibited excellent bond
compatibility with all self-cured resin
cements compared to various 7 th
generation (self-etch) dental adhesive
systems.
• OptiBond XTR’s neutral hydrophobic
adhesive does not interfere with the
basic catalyst components of the
chemically- or dual-cured cements
resulting in increased bond strengths
Data on File,
Kerr Corporation

Shear Bond Strength (MPa)
45
40
35
30
25
20
15
10
5
0
Comparative Indirect Shear Bond Strength
Using Self-Cured Resin Cements
OptiBond XTR Comparative Dentin Bond Strengths with Resin Cements
in Self-Cure Mode vs. 5 th generation Adhesives
Prime & Bond Excite OptiBond XTR
Calibra Variolink II NX3
OptiBond XTR
*Indirect Dentin Bond Strength of 5th Gen Adhesives (with Self-Cured Calibra, Variolink, and NX3
Resin Cement). Activator for each adhesive was omitted. All bonding agents were light-cured. Cements were allowed to self-cure
• OptiBond XTR exhibits superior
compatibility with all self-cured resin
cements compared to various 5 th
generation (total-etch) dental adhesive
systems.
• OptiBond XTR’s neutral hydrophobic
adhesive does not interfere with the
basic catalyst components of the
chemically- or dual-cured cements
resulting in increased bond strengths.
• Prime & Bond and Excite had virtually no
bond strength when tested with Calibra.
Data on File,
Kerr Corporation

Shear Bond Strength (MPa)
OptiBond XTR was NOT light cured. Cements were allowed to self-cure
Comparative Indirect Dentin Shear Bond Strength
Using Self-Cured Resin Cements (No light Curing of
XTR)
OptiBond XTR Comparative Indirect Dentin Bond Strengths with Resin Cements
22
20
18
16
14
12
10
8
6
4
2
0
18.7
19.3
OptiBond XTR + NX3 MultiLink Primer A & B +
MultiLink Cement
11.2
ED Primer AB/Panavia F2.0
Cement
• The combination of OptiBond
XTR + NX3 cement
demonstrated comparable
indirect dentin bond strength to
the Multilink Cementation
System
• OptiBond XTR showed much
higher indirect dentin bond
strength vs. the Panavia
Cementation System
Data on File,
Kerr Corporation

Shear Bond Strength (MPa)
40
35
30
25
20
15
10
5
0
36.6
Bond Durability - Thermocycling
OptiBond XTR Thermocycling Evaluations
29.7
35.7
36.9
24-hour bond strength Bond strength after 5,000 cycles
Dentin Uncut Enamel
• OptiBond XTR exhibited good durability to thermostress
after 5,000 cycles.
Data on File,
Kerr Corporation

Shear Bond Strength (MPa)
40
35
30
25
20
15
10
5
0
*Note, storage study still in progress
Bond Durability – Aqueous Storage
37°C
36.6 35.9
29.7
OptiBond XTR Storage in Water
37.1
33.1 33.4
24-hour Storage 1-week storage 1-month storage
Dentin UnCut Enamel
• OptiBond XTR exhibits good bond durability after
long-term storage in water
Data on File,
Kerr Corporation

OptiBond XTR Direct Technique

OptiBond XTR Indirect Technique
– Restoration Prep

OptiBond XTR Indirect Technique

Summary
OptiBond XTR – Two Component
Universal Self-Etch Adhesive
• Superior bond strength to uncut enamel and dentin
– Enhanced marginal integrity
– Separate acid etching not required
– All indications
• Compatible with all dental materials (light-cure, dual-cure, self-cure)
– Simplifies adhesive techniques and inventory
– Cementation of Opaque or Metal-based restorations, bulk-placement of core materials.
• Low film thickness (5-10 microns)
– Direct and indirect applications
• 15% Filled adhesive with fluoride release and low film thickness
• Easy to use, reduced technique sensitivity
• Excellent bond durability
• Exceptional bond strength to all dental substrates in both Direct and Indirect modes
(dentin/enamel, porcelain, precious alloy, non-precious alloy, Zirconia, composite, titanium)
• Reduces post-op sensitivity: Effective etching/penetration/sealing, high SBS to dentin,
excellent curing of adhesive, and low film thickness