Views
5 years ago

technical guidance documents - Institute for Health and Consumer ...

technical guidance documents - Institute for Health and Consumer ...

technical guidance documents - Institute for Health and Consumer

Institute for Health and Consumer Protection European Chemicals Bureau TGD Part II Technical Guidance Document on Risk Assessment in support of Commission Directive 93/67/EEC on Risk Assessment for new notified substances Commission Regulation (EC) No 1488/94 on Risk Assessment for existing substances Directive 98/8/EC of the European Parliament and of the Council concerning the placing of biocidal products on the market Part II EUROPEAN COMMISSION JOINT RESEARCH CENTRE EUR 20418 EN/2

  • Page 3 and 4: European Commission Technical Guida
  • Page 5: FOREWORD I am pleased to present th
  • Page 9: ENVIRONMENTAL RISK ASSESSMENT Chapt
  • Page 12 and 13: 3 EFFECTS ASSESSMENT ..............
  • Page 14 and 15: 6 TESTING STRATEGIES ..............
  • Page 16 and 17: GENERAL INTRODUCTION product type.
  • Page 18 and 19: GENERAL INTRODUCTION 1.2 GENERAL PR
  • Page 20 and 21: GENERAL INTRODUCTION Table 2 Relati
  • Page 22 and 23: ENVIRONMENTAL EXPOSURE ASSESSMENT c
  • Page 24 and 25: ENVIRONMENTAL EXPOSURE ASSESSMENT P
  • Page 26 and 27: ENVIRONMENTAL EXPOSURE ASSESSMENT c
  • Page 28 and 29: ENVIRONMENTAL EXPOSURE ASSESSMENT f
  • Page 30 and 31: ENVIRONMENTAL EXPOSURE ASSESSMENT s
  • Page 32 and 33: ENVIRONMENTAL EXPOSURE ASSESSMENT T
  • Page 34 and 35: ENVIRONMENTAL EXPOSURE ASSESSMENT 2
  • Page 36 and 37: ENVIRONMENTAL EXPOSURE ASSESSMENT W
  • Page 38 and 39: ENVIRONMENTAL EXPOSURE ASSESSMENT B
  • Page 40 and 41: ENVIRONMENTAL EXPOSURE ASSESSMENT t
  • Page 42 and 43: ENVIRONMENTAL EXPOSURE ASSESSMENT s
  • Page 44 and 45: ENVIRONMENTAL EXPOSURE ASSESSMENT c
  • Page 46 and 47: ENVIRONMENTAL EXPOSURE ASSESSMENT w
  • Page 48 and 49: ENVIRONMENTAL EXPOSURE ASSESSMENT r
  • Page 50 and 51: ENVIRONMENTAL EXPOSURE ASSESSMENT
  • Page 52 and 53:

    ENVIRONMENTAL EXPOSURE ASSESSMENT d

  • Page 54 and 55:

    ENVIRONMENTAL EXPOSURE ASSESSMENT E

  • Page 56 and 57:

    ENVIRONMENTAL EXPOSURE ASSESSMENT 2

  • Page 58 and 59:

    ENVIRONMENTAL EXPOSURE ASSESSMENT 2

  • Page 60 and 61:

    ENVIRONMENTAL EXPOSURE ASSESSMENT

  • Page 62 and 63:

    ENVIRONMENTAL EXPOSURE ASSESSMENT W

  • Page 64 and 65:

    ENVIRONMENTAL EXPOSURE ASSESSMENT T

  • Page 66 and 67:

    ENVIRONMENTAL EXPOSURE ASSESSMENT e

  • Page 68 and 69:

    ENVIRONMENTAL EXPOSURE ASSESSMENT d

  • Page 70 and 71:

    ENVIRONMENTAL EXPOSURE ASSESSMENT T

  • Page 72 and 73:

    ENVIRONMENTAL EXPOSURE ASSESSMENT E

  • Page 74 and 75:

    ENVIRONMENTAL EXPOSURE ASSESSMENT r

  • Page 76 and 77:

    ENVIRONMENTAL EXPOSURE ASSESSMENT T

  • Page 78 and 79:

    ENVIRONMENTAL EXPOSURE ASSESSMENT

  • Page 80 and 81:

    ENVIRONMENTAL EXPOSURE ASSESSMENT 2

  • Page 82 and 83:

    ENVIRONMENTAL EXPOSURE ASSESSMENT E

  • Page 84 and 85:

    ENVIRONMENTAL EXPOSURE ASSESSMENT S

  • Page 86 and 87:

    ENVIRONMENTAL EXPOSURE ASSESSMENT 2

  • Page 88 and 89:

    ENVIRONMENTAL EXPOSURE ASSESSMENT E

  • Page 90 and 91:

    ENVIRONMENTAL EXPOSURE ASSESSMENT D

  • Page 92 and 93:

    ENVIRONMENTAL EXPOSURE ASSESSMENT A

  • Page 94 and 95:

    ENVIRONMENTAL EXPOSURE ASSESSMENT 2

  • Page 96 and 97:

    ENVIRONMENTAL EXPOSURE ASSESSMENT

  • Page 98 and 99:

    ENVIRONMENTAL EXPOSURE ASSESSMENT a

  • Page 100 and 101:

    ENVIRONMENTAL EXPOSURE ASSESSMENT I

  • Page 102 and 103:

    EFFECTS ASSESSMENT equilibrium part

  • Page 104 and 105:

    EFFECTS ASSESSMENT The assessment o

  • Page 106 and 107:

    EFFECTS ASSESSMENT Further details

  • Page 108 and 109:

    EFFECTS ASSESSMENT environments but

  • Page 110 and 111:

    EFFECTS ASSESSMENT For compounds wi

  • Page 112 and 113:

    EFFECTS ASSESSMENT Multiple values

  • Page 114 and 115:

    EFFECTS ASSESSMENT 3.3.2 Effects as

  • Page 116 and 117:

    EFFECTS ASSESSMENT for ciliates are

  • Page 118 and 119:

    EFFECTS ASSESSMENT If on the basis

  • Page 120 and 121:

    EFFECTS ASSESSMENT If no measured d

  • Page 122 and 123:

    EFFECTS ASSESSMENT 3.5.4 Calculatio

  • Page 124 and 125:

    EFFECTS ASSESSMENT A suite of soil

  • Page 126 and 127:

    EFFECTS ASSESSMENT ecotoxicological

  • Page 128 and 129:

    EFFECTS ASSESSMENT other compartmen

  • Page 130 and 131:

    EFFECTS ASSESSMENT effects. This es

  • Page 132 and 133:

    EFFECTS ASSESSMENT • has a log Ko

  • Page 134 and 135:

    EFFECTS ASSESSMENT 3.8.3.2 Calculat

  • Page 136 and 137:

    EFFECTS ASSESSMENT Table 21 Default

  • Page 138 and 139:

    EFFECTS ASSESSMENT hibernation or m

  • Page 140 and 141:

    EFFECTS ASSESSMENT The weight of th

  • Page 142 and 143:

    MARINE RISK ASSESSMENT 4 ENVIRONMEN

  • Page 144 and 145:

    MARINE RISK ASSESSMENT where a desc

  • Page 146 and 147:

    MARINE RISK ASSESSMENT ECETOC (1993

  • Page 148 and 149:

    MARINE RISK ASSESSMENT Readily degr

  • Page 150 and 151:

    MARINE RISK ASSESSMENT assumption.

  • Page 152 and 153:

    MARINE RISK ASSESSMENT • substanc

  • Page 154 and 155:

    MARINE RISK ASSESSMENT More details

  • Page 156 and 157:

    MARINE RISK ASSESSMENT • where ev

  • Page 158 and 159:

    MARINE RISK ASSESSMENT − knowledg

  • Page 160 and 161:

    MARINE RISK ASSESSMENT waters, and

  • Page 162 and 163:

    MARINE RISK ASSESSMENT to be conduc

  • Page 164 and 165:

    MARINE RISK ASSESSMENT available fo

  • Page 166 and 167:

    MARINE RISK ASSESSMENT and most no-

  • Page 168 and 169:

    MARINE RISK ASSESSMENT Explanation

  • Page 170 and 171:

    MARINE RISK ASSESSMENT Derivation o

  • Page 172 and 173:

    MARINE RISK ASSESSMENT Table 30 Cri

  • Page 174 and 175:

    MARINE RISK ASSESSMENT • when a s

  • Page 176 and 177:

    MARINE RISK ASSESSMENT Table 31 Ove

  • Page 178 and 179:

    MARINE RISK ASSESSMENT 4.4.5 Testin

  • Page 180 and 181:

    RISK CARACTERISATION 5 RISK CHARACT

  • Page 182 and 183:

    RISK CARACTERISATION When PEC/PNEC

  • Page 184 and 185:

    RISK CARACTERISATION A specific ris

  • Page 186 and 187:

    RISK CARACTERISATION The base set t

  • Page 188 and 189:

    RISK CARACTERISATION For a qualitat

  • Page 190 and 191:

    TESTING STRATEGIES Another possible

  • Page 192 and 193:

    TESTING STRATEGIES 6.3 REFINEMENT O

  • Page 194 and 195:

    TESTING STRATEGIES 6.3.2.2 Availabl

  • Page 196 and 197:

    TESTING STRATEGIES Table 34 Decisio

  • Page 198 and 199:

    TESTING STRATEGIES during the test

  • Page 200 and 201:

    TESTING STRATEGIES Earthworm acute

  • Page 202 and 203:

    REFERENCES 7 REFERENCES Ahlers J, K

  • Page 204 and 205:

    REFERENCES ECETOC (1993). Assessmen

  • Page 206 and 207:

    REFERENCES Mackay D, Paterson S, Sh

  • Page 208 and 209:

    REFERENCES OECD (2000c). Aerobic an

  • Page 210 and 211:

    REFERENCES SETAC (1992). Workshop o

  • Page 213 and 214:

    Appendix I Emission factors for dif

  • Page 215 and 216:

    8. Aspects of waste treatment APPEN

  • Page 217 and 218:

    APPENDIX I A table is presented for

  • Page 219 and 220:

    APPENDIX I production of printed ci

  • Page 221 and 222:

    APPENDIX I Table for IC 8 of the MC

  • Page 223 and 224:

    APPENDIX I For this IC both emissio

  • Page 225 and 226:

    Stage Main category Ia Ib Ic II III

  • Page 227 and 228:

    2. 3. 4. 5. Formulation RELEASE2,j

  • Page 229 and 230:

    IC = 1: AGRICULTURAL INDUSTRY PRODU

  • Page 231 and 232:

    IC=2: CHEMICAL INDUSTRY: BASIC CHEM

  • Page 233 and 234:

    IC = 4: ELECTRICAL/ELECTRONIC INDUS

  • Page 235 and 236:

    Table A4.1 continued Compartment Co

  • Page 237 and 238:

    IC = 6: PUBLIC DOMAIN PRODUCTION Ta

  • Page 239 and 240:

    IC = 8: METAL EXTRACTION, REFINING

  • Page 241 and 242:

    IC = 10: PHOTOGRAPHIC INDUSTRY PROD

  • Page 243 and 244:

    IC = 11: POLYMERS INDUSTRY PRODUCTI

  • Page 245 and 246:

    IC = 12: PULP, PAPER AND BOARD INDU

  • Page 247 and 248:

    IC = 13: TEXTILE PROCESSING INDUSTR

  • Page 249 and 250:

    IC = 14: PAINTS, LACQUERS AND VARNI

  • Page 251 and 252:

    IC = 16: ENGINEERING INDUSTRY: CIVI

  • Page 253 and 254:

    IC = 0: OTHERS PRODUCTION Table A1.

  • Page 255 and 256:

    IC = 1: AGRICULTURAL INDUSTRY PRODU

  • Page 257 and 258:

    IC = 2: CHEMICAL INDUSTRY: BASIC CH

  • Page 259 and 260:

    IC = 4: ELECTRICAL/ELECTRONIC INDUS

  • Page 261 and 262:

    IC = 6: PUBLIC DOMAIN PRODUCTION Ta

  • Page 263 and 264:

    IC = 8: METAL EXTRACTION, REFINING

  • Page 265 and 266:

    IC = 10: PHOTOGRAPHIC INDUSTRY PROD

  • Page 267 and 268:

    IC = 12: PULP, PAPER AND BOARD INDU

  • Page 269 and 270:

    IC = 14: PAINTS, LACQUERS AND VARNI

  • Page 271 and 272:

    IC = 0 (OTHERS) PRODUCTION Table B1

  • Page 273 and 274:

    No. Use Category No. Function (Chem

  • Page 275 and 276:

    No. Use Category No. Function (Chem

  • Page 277 and 278:

    No. Use Category No. Function (Chem

  • Page 279 and 280:

    No. Use Category No. Function (Chem

  • Page 281 and 282:

    183 Deposit modifiers 28 367 Depres

  • Page 283 and 284:

    Appendix I-c: Input scheme for emis

  • Page 285 and 286:

    6. Processing characteristics N.B.

  • Page 287 and 288:

    a) No biodegradability APPENDIX II

  • Page 289 and 290:

    APPENDIX II c) pass levels within 2

  • Page 291 and 292:

    log H % degraded -4 -3 -2 -1 0 1 2

  • Page 293 and 294:

    APPENDIX III not be available and e

  • Page 295 and 296:

    Appendix IV Assignment of organisms

  • Page 297 and 298:

    APPENDIX V Appendix V Examples of a

  • Page 299 and 300:

    291 Table 1 continued Selected soil

  • Page 301 and 302:

    293 Table 1 continued Selected soil

  • Page 303 and 304:

    295 Table 1 continued Selected soil

  • Page 305 and 306:

    Appendix VI Examples of assays suit

  • Page 307 and 308:

    299 Table 1 continued Selected fres

  • Page 309 and 310:

    Appendix VIII Environmental risk as

  • Page 311 and 312:

    APPENDIX VIII can make a significan

  • Page 313 and 314:

    APPENDIX VIII concentrations may be

  • Page 315 and 316:

    In a natural soil or sediment syste

  • Page 317 and 318:

    Derivation of the PNEC APPENDIX VII

  • Page 319 and 320:

    Appendix IX Environmental risk asse

  • Page 321 and 322:

    APPENDIX IX Summarising, once the

  • Page 323 and 324:

    APPENDIX IX present in low concentr

  • Page 325 and 326:

    APPENDIX IX available to allow anyt

  • Page 327 and 328:

    Appendix X Transformation pathways

  • Page 329 and 330:

    APPENDIX XI and Kow need to be dete

  • Page 331 and 332:

    Table 1 Proportion of the Populatio

  • Page 333 and 334:

    APPENDIX XIII Appendix XIII Risk as

  • Page 335 and 336:

    APPENDIX XIV Appendix XIV Informati

  • Page 337:

    The mission of the JRC is to provid

and the Technical Guidance Document - at RegisGate.com
Technical Guidance Document for Environmental Impact ...
Technical Guidance Document for Wastewater and Marine Water ...
Technical Guidance Document for Wastewater and Marine Water ...
Technical Guidance Document for Construction Environmental ...
Technical Guidance Document for Terms of Reference (TOR)
Technical Guidance For Deriving Environmental ... - Oekotoxzentrum
Occupational Health Program Guidance Document for Working with ...
BBP Refresher Guidance Document - Environmental Health & Safety
Technical Guidance Document for Submission of Environmental ...
Occupational Health Program Guidance Document for Working with ...
Technical Guidance Document for Environmental Audit Reports
Technical Guidance Document for Environmental Action Plan (EAP)
Technical Guidance Document for Terms of Reference (TOR)
Technical Guidance Document for Environmental Impact Assessment
Download 1997 technical guidance document 5 - States of Jersey
Cancer and the Environment - NIEHS - National Institutes of Health
Nanosafe 2012 - Institute for Health and Consumer Protection
content - Institute for Health and Consumer Protection
JRC report_QSAR tools - Institute for Health and Consumer ...
Working Document Guidance Document on Aquatic Ecotoxicology
GUIDANCE DOCUMENT - Georgia Environmental Protection Division
Monitored Natural Attenuation Technical Guidance Document
guidance document - Marine Institute
Technical Guidance Document B - Fire Safety - Department of ...
Technical Guidance Document on the Use of Socio ... - OECD
JRC report_genotoxicity QSAR - Institute for Health and Consumer ...
CMAQ v4.6 Operational Guidance Document - Institute for the ...
Guidance Document - Minnesota Department of Health
Health Risk Assessment Guidance - American Geriatrics Society