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cv_kuner_rohini (PDF / 192.6 KB) - CellNetworks

Dr. Rohini Kuner

Institute for Pharmacology

University Heidelberg

D-69120 Heidelberg, Germany

Phone: +49-(0)6221-548289

Fax: +49-(0)6221-548549

E-mail: rohini.kuner@pharma.uni-heidelberg.de

28/07/1970, India Group Leader in the DFG Emmy-Noether Program

SCIENTIFIC VITA

1994 PhD in Pharmacology und Toxicology,Dept. of Pharmacology, College of

Medicine, University of Iowa, Iowa City, USA

1995-1998 Postdoc ZMBH, University of Heidelberg and Department of Molecular

Neurobiology, Max-Planck-Institut for Medical Research, Heidelberg

1998-2000 Scientist, BASF-Lynx AG, Heidelberg

2000-2001 Scientist, Pharmacology Institute, Univ. Heidelberg

2002- Group leader of an independent, DFG-financed Emmy Noether-program

group, Pharmacology Institute, Univ. Heidelberg

2005 Habilitation, Medical faculty of the University of Heidelberg

2006 Offer for full professorship at the University of Marburg

SCIENTIFIC PRIZES

2005 Rudolf-Buchheim Annual Prize of the German Society for Experimental and

Clinical Pharmacology and Toxicology

2006 Chica and Heinz Schaller Prize

FIELDS OF INTEREST

Molecular mechanisms of synaptic plasticity in neurological functions, Pathophysiology and

molecular mechanisms of chronic inflammatory pain diseases and chronic cancer pain,

Structural plasticity of nerves, Conditional mutagenesis, Development of novel therapeutic

approaches, Roles of Plexins and Semaphorins in development of neural systems

CURRENTLY FUNDED PROJECTS

DFG Emmy Noether Program; DFG SFB488, project B6; DFG KFG107, project 7;

Landesstiftung Baden-Württemberg, Association for International Cancer Research, UK.

Currently supervision of 1 diploma thesis, 8 doctoral theses


PUBLICATIONS (10 selected publications since 2000):

Tappe, A. and Kuner, R. 2006. Regulation of motor performance and striatal function by

synaptic scaffolding proteins of the Homer1 family, Proc. Natl. Acad. Sci. USA. 103: 774-779.

Kuner, R., Groom, A., Bresink, I., Kornau, H.C., Stefovska, V., Müller, G., Hartmann, B.,

Tschauner, K., Waibel, S., Ludolph, A.C., Ikonomidou, C., Seeburg, P.H. & Turski, L. 2005.

Late-onset motoneuron disease caused by transgenic expression of a functionally modified

AMPA receptor subunit, Proc. Natl. Acad. Sci. USA. 102: 5826-5831.

Dreyer, J., Schleicher, M., Tappe, A., Schilling, K., Kuner, T., Kusumawidijaja, G., Müller-

Esterl, W., Oess, S. and Kuner, R. 2004. (NOS)-interacting protein interacts with neuronal

NOS and regulates its distribution and activity, J. Neurosci. 24(46): 10454-10465.

Hartmann, B., Ahmadi, S., Heppenstall, P., Zeilhofer, H.U., Lewin, G., Schott, C., Seeburg,

P.H., Sprengel, R. & Kuner, R. 2004. he AMPA receptor subunits, GluR-A and GluR-B

reciprocally modulate spinal synaptic plasticity and inflammatory pain, Neuron 44: 637-650.

Swiercz, J.M., Kuner, R. & Offermanns, S. 2004. Plexin-B1/RhoGEF-mediated RhoA

activation involves the receptor tyrosine kinase ErbB-2, J. Cell Biol. 165: 869-880.

Worzfeld, T., Püschel, A., Offermanns, S., Kuner, R. 2004. Plexin-B family members

demonstrate non-redundant expression patterns in the developing mouse nervous system: A

anatomical basis for morphogenetic effects of Sema4D during development, Eur J Neurosci.

19: 2622-2632.

Agarwal, N., Offermanns, S. and Kuner, R. 2004. Conditional gene targeting in neurons of

the dorsal root ganglia and trigeminal ganglia, Genesis 38/3: 122-129.

Dreyer, J., Hirlinger, D., Müller-Esterl, W,. Oess, S., Kuner, R. 2003. Spinal upregulation of

the nitric oxide synthase-interacting protein NOSIP in a rat model of inflammatory pain,

Neurosci. Lett. 350:13-16.

Kuner, R., Swiercz, J.M., Zywietz, A., Tappe, A., Offermanns, S. 2002. Characterization of

the expression of PDZ-RhoGEF, LARG and Galpha12/Galpha13 proteins in the murine

nervous system. Eur J Neurosci. 16: 2333-41.

Swiercz, J.M.*, Kuner, R.*, Behrens, J., Offermanns, S. 2002. Plexin-B1 directly interacts

with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology. Neuron 35: 51-63.

* equal contribution

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