156 7 Pharmacological App

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156 7 Pharmacological Approaches to Improve Surgical Outcomes 5. Cowley M, Conway B, Campochiaro P, Kaiser D, Gaskin H (1989) Clinical risk factors for proliferative vitreoretinopathy. Arch Ophthalmol 107:1147–1151 6. Grizzard WS, Hilton GF (1982) Scleral buckling for retinal detachments complicated by periretinal proliferation.Arch Ophthalmol 100: 419–422 7. Sternberg P Jr, Machemer R (1985) Results of conventional vitreous surgery for proliferative vitreoretinopathy. Am J Ophthalmol 100: 141–146 8. Blumenkranz M, Hernandez E, Ophir A, Norton EWD (1984) 5-Fluorouracil: new applications in complicated retinal detachment for an established antimetabolite. Ophthalmology 91:122– 130 9. Blumenkranz MS (1988) Management of complicated retinal detachment. In: Tso MOM (ed) <strong>Retinal</strong> diseases: biomedical foundations and clinical management. JB Lippincott, Philadelphia 10. Asaria RH, Kon CH, Bunce C, Charteris DC et al (2001) How to predict proliferative vitreoretinopathy: a prospective study. Ophthalmology 108:1184–1186 11. Martidis A, Duker JS, Greenberg PB, Rogers AH et al (2002) Intravitreal triamcinolone for refractory diabetic macular edema. Ophthalmology 109:920–927 12. Greenberg PB, Martidis A, Rogers AH, Duker JS, Reichel E (2002) Intravitreal triamcinolone acetonide for macular oedema due to central retinal vein occlusion. Br J Ophthalmol 86:247–248 13. Koerner F, Merz A, Gloor B, Wagner E (1982) Postoperative retinal fibrosis – a controlled clinical study of systemic steroid therapy. Graefes Arch Clin Exp Ophthalmol 219:268–271 14. Machemer R (1977) Massive periretinal proliferation: a logical approach to therapy. Trans Am Ophthalmol Soc 75:556–586 15. Blumenkranz MS, Hartzer MK (2000) The mechanism of action of drugs for the treatment of vitreoretinal scarring. In: Retina, vol. 3. Ryan S, Glaser B (eds) CV Mosby, St. Louis, pp 2281–2293 16. Campochiaro PA, Bryan JA III, Conway BP, Jaccoma EH (1986) Intravitreal chemotactic and mitogenic activity implications of bloodretinal barrier breakdown. Arch Ophthalmol 104:1685–1687 17. Campochiaro PA, Glaser BM (1986) Mechanisms involved in retinal pigment epithelial cell chemotaxis. Arch Ophthalmol 104: 277–280
References 157 18. Yeo JH, Sadeghi J, Campochiaro PA, Green WR, Glaser BM (1986) Intravitreous fibronectin and platelet-derived growth factor: new model for tractional retinal detachment.Arch Ophthalmol 104:417–421 19. Verdoorn C, Renardel de Lavalette VW, Dalma-Weizhaus J, Orr GM, Sorgente N, Ryan SJ (1986) Cellular migration, proliferation and contraction: an in vitro approach to a clinical problem – proliferative vitreoretinopathy. Arch Ophthalmol 104:1216–1219 20. Vidaurri-Leal J, Glaser B (1984) Effect of fibrin on morphologic characteristics of retinal pigment epithelial cells. Arch Ophthalmol 102:1376–1379 21. Vidaurri-Leal J, Hohman R, and Glaser BM (1984) Effect of vitreous on morphologic characteristics of retinal pigment epithelial cells: a new approach to the study of proliferative vitreoretinopathy. Arch Ophthalmol 102:1220–1223 22. Blumenkranz MS, Ophir A, Claflin A, Hajek AS (1982) Fluorouracil for the treatment of massive periretinal proliferation. Am J Ophthalmol 94:458–467 23. Stern WH, Lewis GP, Erickson PA, Guerin CJ,Anderson DH, Fisher SK, O’Donnell JJ (1983) Fluorouracil therapy for proliferative vitreoretinopathy after vitrectomy. Am J Ophthalmol 96:33–42 24. Tano Y, Sugita G, Abrams G, Machemer R (1980) Inhibition of intraocular proliferations with intravitreal corticosteroids. Am J Ophthalmol 89:131–136 25. Van Bockxmeer FM, Martin CE, Constable IJ (1985) Models for assessing scar tissue inhibitors. Retina 5:47–60 26. Wiedemann P, Lemmen K, Schmiedl R, Heimann K (1987) Intraocular daunorubicin for the treatment and prophylaxis of traumatic proliferative vitreoretinopathy. Am J Ophthalmol 104:10–14 27. Anonymous (1992) Vitrectomy with silicone oil or sulfur hexafluoride gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 1. Arch Ophthalmol 110:770–779 28. Anonymous (1992) Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 2. Arch Ophthalmol 110:780–792 29. Jolimaitre P, Malet-Martino M, Martino R (2003) Fluorouracil prodrugs for the treatment of proliferative vitreoretinopathy: formulation in silicone oil and in vitro release fluorouracil. Int J Pharm 259:181–192
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Ingrid Kreissig (Ed.) Primary Retin
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Professor Dr. med. Ingrid Kreissig
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Contents 1 The History of Retinal D
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List of Contributors Gary W. Abrams
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List of Contributors XI Hermann D.
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2 Helmholz in 1850 made an accurate
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4 (vitreous, gelatin) into the ante
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6 with scleral resection that set t
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8 ditis [72-74].Temperatures up to
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10 1 The History of Retinal Detachm
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16 ion [147]. Perfluorocarbon liqui
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26 2 Prophylaxis in Fellow Eye of P
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32 found that eyes with pre-existin
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36 3 Encircling Operation with Drai
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Chapter 4 Pneumatic Retinopexy for
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Technique 57 Case Selection Proper
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Technique 59 Table 4.1. Gas charact
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Technique 61 solution; however,thes
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Technique 63 gas reflux. Following
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Complications: Prevention and Manag
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New Possibilities 67 ing on type an
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Results 69 Table 4.7 (continued) Au
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Discussion 71 surgical failures. Fa
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Discussion 73 Disadvantages of PR A
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References 75 situations, then to p
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References 77 24. Tornambe PE, Hilt
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References 79 51. Pournaras CJ, Don
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Chapter 5 Vitrectomy for the Primar
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Indications 83 Table 5.1. Indicatio
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Indications 85 Fig. 5.2. The vitreo
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Surgical Technique 87 vitrectomy an
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Outcomes 89 will be visible under a
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Outcomes 91 almost no persistent su
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References 93 7. Heimann H, Bornfel
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96 6 Minimal Segmental Buckling Wit
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98 6 Minimal Segmental Buckling Wit
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100 the operating table with the re
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102 6 Minimal Segmental Buckling Wi
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104 6 Minimal Segmental Buckling Wi
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Page 132 and 133: 124 c Fig. 6.14c 6 Minimal Segmenta
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Page 138 and 139: 130 Choroidals In 4 of the 1,462 de
Page 140 and 141: Table 6.4. Visual acuity at 2 years
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Page 162 and 163: 154 search for compounds with hepar
Page 168 and 169: Chapter 8 Systematic Review of Effi
Page 170 and 171: Materials and Methods 163 Table 8.2
Page 172 and 173: Discussion 165 30% 25% 20% 15% 10%
Page 174 and 175: Discussion 167 Fig. 8.2. The small
Page 176 and 177: Conclusion 169 vitrectomy and searc
Page 178 and 179: References 171 8. Brazitikos PD, D
Page 180 and 181: References 173 34. Gunduz K, Gunalp
Page 182 and 183: References 175 63. Schepens CL (195
Page 184 and 185: 178 9 Repair of Primary Retinal Det
Page 186 and 187: 180 a b Fig. 9.3a,b. Legend see pag
Page 192 and 193: 186 a b 9 Repair of Primary Retinal
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Page 200 and 201: Retinal Detachment Repair: Outlook
Page 212 and 213: References 207 It is impossible to
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210 C Campbell 7 case selection 57,
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212 M Machemer 13 macular - complic
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214 retinal - detachment - - bilate
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