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Dengue Bulletin

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E<br />

From the Editor’s desk<br />

pidemic dengue fever/dengue haemorrhagic fever (DF/DHF) continues to be a<br />

major public health problem globally. The wide geographic spread of both the<br />

vectors and the viruses over the last 30 years have led to the development of<br />

hyperendemicity in several urban areas in the tropics. Before the 1970s, only nine<br />

countries had epidemic DHF. Today, the number has increased several fold. During<br />

2001-2002, the World Health Organization estimated about 50 million infections with<br />

over 500,000 cases of DHF with at least 12,000 deaths, mainly among children. A<br />

reversal of these trends is the major challenge facing the health communities globally.<br />

Endemic countries are striving hard to improve surveillance, particularly pro-active<br />

surveillance which entails collection of blood samples to detect the virus genome and<br />

to help predict DHF outbreaks. Cost-effective and sustainable interventions, rapid<br />

diagnostics and improved case management to reduce both morbidity and mortality<br />

are being pursued vigorously by these countries.<br />

New “innovations” related to: (i) selective indoor residual spray of cryptic resting<br />

sites of Aedes aegypti, instead of insecticidal fogging, for control of DHF epidemics; (ii)<br />

inexpensive and rapid diagnostic test based on the nucleic acid sequence-based<br />

amplication (NASBA) as an alternate to PCR which requires specialized training and<br />

specific equipment, such as thermalcycler, and (iii) detection of dengue virus genome<br />

among travellers to South-East Asian countries and its importance as a good predictive<br />

for larger epidemics in “travellers contact” countries are the major highlights of this<br />

volume.<br />

It is heartening to note that the <strong>Dengue</strong> <strong>Bulletin</strong>, which initially focused on<br />

WHO’s South-East Asia and Western Pacific Regions, has now reached new heights<br />

and has gone global. Volume 26, includes contributions from four WHO Regions, viz.<br />

South-East Asia, Western Pacific, American and Eastern Mediterranean.<br />

The popularity of the <strong>Bulletin</strong> can be gauged by the fact that we have closed<br />

contributions for Volume 27 which is due for publication by the end of 2003. We are<br />

now inviting contributions for Volume 28. The deadline for the receipt of contributions<br />

is 31 January 2004. Contributors are requested to follow the instructions carefully while<br />

preparing the manuscript. Contributions accompanied by computer diskettes using MS<br />

Word for Windows should be sent to the Editor, <strong>Dengue</strong> <strong>Bulletin</strong>, WHO/SEARO,<br />

Mahatma Gandhi Road, I. P. Estate, Ring Road, New Delhi-110 002, India, or by email<br />

as a file attachment to the Editor at dengue@whosea.org.<br />

Readers desirous of obtaining copies of the <strong>Dengue</strong> <strong>Bulletin</strong> may contact the<br />

respective WHO Regional Offices in New Delhi or Manila or the WHO Country<br />

Representative in their country of residence.<br />

Dr Chusak Prasittisuk<br />

Regional Adviser<br />

Vector-Borne Disease Control<br />

World Health Organization<br />

Regional Office for South-East Asia<br />

New Delhi

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