differenziamento in vitro di cellule ossee

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Seeman E and Delmas P. N Engl J Med 2006;354:2250-2261
RIMODELLAMENTO OSSEO IN CONDIZIONI FISIOLOGICHE Osteoclast Precursors Differentiated Osteoclast Riassorbimento osseo Osteoblasts Osteodeposizione
Page 1 and 2: Transdifferenziazione e differenzia
Page 3: 5% 94% 1%
Page 7: Skeletal Integrity in Oncology clin
Page 10 and 11: Pre OCs c-FMS c-FMS RANK RANK of ma
Page 12 and 13: © 2005 Rockefeller University Pres
Page 15 and 16: Dopo 24 ore di coltura si recupera
Page 17: Osteoclasta coltivato su fettina di
Page 20 and 21: DKK-1 kremen LRP5/6 APC Axin Citopl
Page 22 and 23: OSTEOBLASTI E ADIPOCITI HANNO UN PR
Page 24 and 25: ISOLAMENTO DELLE MSC DA MIDOLLO OSS
Page 26 and 27: Differenziamento osteogenico Il dif
Page 28 and 29: Conoscere i processi differenziativ
Page 30 and 31: Incidence of Bone Metastases in Can
Page 32 and 33: Bone Is Removed by Osteoclast Activ
Page 34 and 35: Pathogenesis of Multiple Myeloma Bo
Page 36 and 37: Formazione di OCs da PBMCs di sogge
Page 38 and 39: - + T cells depleted MM PBMC cultur
Page 40 and 41: Alterazione dell’asse RANKL/OPG e
Page 42 and 43: Il RANKL è implicato nella perdita
Page 44 and 45: Role of OPG in the Regulation of Bo
Page 46 and 47: Denosumab Is the First Fully Human
Page 48 and 49: Pharmacologic Properties of • Ful
Page 50 and 51: Pathogenesis of Multiple Myeloma Bo
Page 53 and 54: Osteoblast suppression in MM bone d
Page 55 and 56:
•Sclerostin, encoded by SOST gene
Page 57 and 58:
Aim of the work Investigate the exp
Page 59 and 60:
…Co-coltures between bone marrow
Page 61 and 62:
H929 anti-Sclerostin (ng/ml) Effect
Page 63 and 64:
WNT signaling regulates RANKL/OPG a
Page 65 and 66:
Sclerostin Myeloma cells through sc
Page 67 and 68:
Riassorbimento dell’osso alveolar
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