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Análise da biocompatibilida<strong>de</strong> <strong>de</strong> cones <strong>de</strong> biovidro e biovitrocerâmico (Biosilica<strong>to</strong> ® ) em cavida<strong>de</strong> eviscerada <strong>de</strong> coelho<br />

25<br />

A avaliação do colágeno <strong>de</strong>monstrou diferença estatística<br />

no grupo biovitrocerâmico FI, entre os M1 e M2, porém valores<br />

não al<strong>to</strong>s e nem mui<strong>to</strong> diferentes aos observados nos grupos<br />

biovidro e biovitrocerâmico FII. Com estas observações po<strong>de</strong>se<br />

afirmar que os cones implantados não geraram resposta <strong>in</strong>flamatória<br />

exacerbada e não produziram cicatrização anormal ou<br />

fibrose importante no local <strong>de</strong> conta<strong>to</strong> entre o cone e o tecido do<br />

hospe<strong>de</strong>iro.<br />

CONCLUSÃO<br />

A partir dos achados po<strong>de</strong>-se dizer que os cones <strong>de</strong> biovidro<br />

e biovitrocerâmico FI e FII, quando colocados nas cavida<strong>de</strong>s<br />

evisceradas <strong>de</strong> coelhos não apresentam s<strong>in</strong>ais <strong>de</strong> <strong>to</strong>xicida<strong>de</strong><br />

sistêmica ou local. A análise morfológica apon<strong>to</strong>u para a superiorida<strong>de</strong><br />

dos cones <strong>de</strong> biovidro e biovitrocerâmico FI, os quais<br />

apresentaram menor reação <strong>in</strong>flamatória e menor formação da<br />

pseudocápsula que os cones <strong>de</strong> biovitrocerâmico FII. Desta forma,<br />

os au<strong>to</strong>res concluem que os cones <strong>de</strong> biovidro e<br />

biovitrocerâmico FI e FII po<strong>de</strong>m ser úteis para a reparação da<br />

cavida<strong>de</strong> anoftálmica, com melhor resposta quando se usa os<br />

cones <strong>de</strong> biovidro e biovitrocerâmico FI.<br />

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Au<strong>to</strong>r correspon<strong>de</strong>nte:<br />

Departamen<strong>to</strong> <strong>de</strong> Oftalmologia, O<strong>to</strong>rr<strong>in</strong>olar<strong>in</strong>gologia e<br />

Cirurgia <strong>de</strong> Cabeça e Pescoço da Faculda<strong>de</strong> <strong>de</strong> Medic<strong>in</strong>a<br />

<strong>de</strong> Botucatu (UNESP)<br />

CEP 18618-000 – Botucatu (SP), Brasil<br />

Email: similani@terra.com.br<br />

Rev Bras Oftalmol. 2013; 72 (1): 21-5

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