Karen Amaral Tavares Pinheiro - Universidade Católica de Pelotas
112 comes from a variety of studies in major depressed/suicidal subjects that demonstrate a reduction in the cell number, density and body size, as well as the a reduction in neuronal and glial density in the frontal cortical or hippocampal brain areas. Interestingly, the functional role of BDNF is critically associated with synaptic transmission and neuroplasticity, which are disturbed in subjects with psychiatric disorders 5 . Acknowledgments This work was supported by the Brazilian grants CNPq, CAPES, PRONEX- FAPERGS and FINEP IBN-Net as well as by the INCT-Excitotoxicity and Neuroprotection.
113 References 1. KELLY E, SHARMA V. Diagnosis and treatment of postpartum bipolar depression. Expert Rev. Neurother. 2010;10(7), 1045–1051. 2. ROT M, MATHEW SJ, CHARNEY DS. Neurobiological mechanisms in major depressive disorder. CMAJ 2009;3, 180–183. 3. PINHEIRO RT, DA SILVA RA, MAGALHÃES PV, HORTA BL, PINHEIRO KA. Two studies on suicidality in the postpartum. Acta. Psychiatr. Scand. 2008;118(2), 160–163. 4. LINDAHL V, PEARSON JL, COLPE L. Prevalence of suicidality during pregnancy and the postpartum. Arch Womens Ment Health 2005; 8:77–87. 5. DWIVEDI Y. Brain-derived neurotrophic factor: role in depression and suicide. Neuropsychiatr. Dis. Treat. 2009;5, 433–434. 6. KRISHNAN V, NESTLER EJ. The molecular neurobiology of depression. Nature 2008;455(7215),894–902. 7. STEIN DJ, DANIELS WMU, SAVITZ J, HARVEY BH. Brain-derived Neurotrophic Factor: Hypothesis of Psychopathology. CNS Spectr. 2008;13(11), 945–949. 8. TSAI SJ,. Possible involvement of the BDNF-dependent pathway in treatmentemergent suicidality or decreased response to antidepressants. Med. Hypotheses. 2005; 65(5), 942–946. 9. DWIVEDI Y.. Brain-derived neurotrophic factor and suicide pathogenesis. Ann. Med. 2010;42(2), 87–96. 10. KIM YK, LEE HP, WON SD, et al.,. Low plasma BDNF is associated with suicidal behavior in major depression. Prog. Neuropsychopharmacol. Biol. Psychiatry. 2007;31(1),78–85.
1 UNIVERSIDADE CATÓLICA DE PELOTAS
3 Transtornos do humor no período
5 AGRADECIMENTOS Ao meu orientador
7 ÍNDICE INTRODUÇÃO GERAL ......
9 INTRODUÇÃO GERAL Diversas alter
11 PARTE I - PROJETO I. IDENTIFICA
13 nos casos em que o suicídio é
15 IX. Os problemas de sono em beb
17 oportunizando menos interações
19 risco de desordens psicopatológ
21 I V. MÉTODOS 4.1. Delineamento
23 identificar crianças com atraso
25 Um questionário com variáveis
27 4.5. Pessoal Envolvido A equipe
29 Trinta dias após o nascimento d
31 4.12. Cronograma Atividades 1 2
33 12.Glasser, D. Child abuse and n
35 33.Kapczinski F, Quevedo J. Tran
VI. ANEXOS 37