Referenţi ştiinţifici - Muzeul Judeţean Satu Mare
Referenţi ştiinţifici - Muzeul Judeţean Satu Mare
Referenţi ştiinţifici - Muzeul Judeţean Satu Mare
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
<strong>Satu</strong> <strong>Mare</strong> – Studii şi Comunicări Ştiinţele Naturale -– Vol. VI (2005)<br />
La lotul investigat prevalenţa generală a dislipidemiei a fost de 67,4% IC95%.<br />
Concluzii<br />
Se confirmă ca şi factori de risc pentru PDSM:<br />
- Fumatul - asociere semnificativ statistică,<br />
(p=0,0009);<br />
- HTA - am putut stabili o corelaţie<br />
semnificativă statistic, (p=0,0019) pentru<br />
tipul 1 de DZ; similar şi pentru DZ tip 2,<br />
(p=0,0027);<br />
- Trigliceride peste 150 mg/dl - există o<br />
relaţie pozitivă, semnificativă statistic<br />
(p=0,00059); RR=1,3783.<br />
- In concluzie se pot emite câteva consideraţii:<br />
1. Identificarea şi tratarea FR pentru neuropatie,<br />
potenţial modificabili (nivelul trigliceridelor serice, IMC,<br />
fumatul şi HTA) ar putea scădea prevalenţa<br />
polineuropatiei.<br />
2. Este imperios necesar ca trialurile<br />
intervenţionale să includă pe viitor în designe-ul lor:<br />
controlul glicemic, abandonarea fumatului, controlul TA,<br />
intervenţii asupra lipidelor.<br />
Bibliografie<br />
1. American Diabetes Association. Standards of<br />
medical care for patients with diabetes mellitus. Diabetes<br />
Care 26: S33-S50, 2003<br />
2. Executive summary of the third report of the National<br />
Cholesterol Education Program (NCEP) expert panel on<br />
detection, evaluation, and treatment of high blood<br />
cholesterol in adults (Adult Treatment Panel III).<br />
Expert Panel on Detection, Evaluation, and Treatment<br />
of High Blood Cholesterol in Adults JAMA 285:<br />
2486-2497, 2001<br />
3. Boulton A.J.M., Gries F.A., Jervell J.: Guidelines for the<br />
diagnostic and out–patient management of diabetic<br />
peripheral neuropathy. Diabet med.15: 508-514, 1998<br />
4. Dyck PJ, Sherman WR, Hallcher LM, et al. Human<br />
diabetic endoneurial sorbitol, fructose and myo-inositol related<br />
to sural nerve morphometry. Ann Neurol; 8: 590-596, 1980<br />
5. 18. Crişan C, Suciu G, Szabo M. The obesity prevalence<br />
in the population of the Mureş county. Primul Congres<br />
Naţional al Asociaţiei Române pentru Studiul<br />
Obezităţii, Cluj-Napoca; 18-20 octombrie, 2001<br />
6. Consensus Statement. Treatment of Hypertension in<br />
Diabetes. Diabetes Care16, 10: 1394-1401, 1993<br />
7. 27. World Health Organization-International Society of<br />
Hypertension. Guidelines for the Management of<br />
Hypertension. Journal of Hypertension 17: 151-183,<br />
1999<br />
8. The EURODIAB Prospective Complications Study<br />
(PCS) Group: Cardiovascular risk factors predict diabetic<br />
peripheral neuropathy in type 1 subjects in Europe.<br />
Diabetologia 42:A50–A181, 1999<br />
9. Maser RE, Steenkiste AR, Dorman JS et al.<br />
Epidemiological correlates of diabetic neuropathy: report from<br />
Pittsburg Epidemiology of Diabetes Complications Study.<br />
Diabetes; 38; 1456-1461, 1989<br />
10. 31. Feldman EL. Oxidative stress and diabetic neuropathy:<br />
a new understanding of an old problem. J Clin Invest 111:<br />
431-433, 2003<br />
11. Haffner SM. Dyslipidemia management in adults with<br />
diabetes. Diabetes Care; 27: Suppl 1: S68-S71, 2004<br />
271