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Referenţi ştiinţifici - Muzeul Judeţean Satu Mare

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<strong>Satu</strong> <strong>Mare</strong> – Studii şi Comunicări Ştiinţele Naturale -– Vol. VI (2005)<br />

La lotul investigat prevalenţa generală a dislipidemiei a fost de 67,4% IC95%.<br />

Concluzii<br />

Se confirmă ca şi factori de risc pentru PDSM:<br />

- Fumatul - asociere semnificativ statistică,<br />

(p=0,0009);<br />

- HTA - am putut stabili o corelaţie<br />

semnificativă statistic, (p=0,0019) pentru<br />

tipul 1 de DZ; similar şi pentru DZ tip 2,<br />

(p=0,0027);<br />

- Trigliceride peste 150 mg/dl - există o<br />

relaţie pozitivă, semnificativă statistic<br />

(p=0,00059); RR=1,3783.<br />

- In concluzie se pot emite câteva consideraţii:<br />

1. Identificarea şi tratarea FR pentru neuropatie,<br />

potenţial modificabili (nivelul trigliceridelor serice, IMC,<br />

fumatul şi HTA) ar putea scădea prevalenţa<br />

polineuropatiei.<br />

2. Este imperios necesar ca trialurile<br />

intervenţionale să includă pe viitor în designe-ul lor:<br />

controlul glicemic, abandonarea fumatului, controlul TA,<br />

intervenţii asupra lipidelor.<br />

Bibliografie<br />

1. American Diabetes Association. Standards of<br />

medical care for patients with diabetes mellitus. Diabetes<br />

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Expert Panel on Detection, Evaluation, and Treatment<br />

of High Blood Cholesterol in Adults JAMA 285:<br />

2486-2497, 2001<br />

3. Boulton A.J.M., Gries F.A., Jervell J.: Guidelines for the<br />

diagnostic and out–patient management of diabetic<br />

peripheral neuropathy. Diabet med.15: 508-514, 1998<br />

4. Dyck PJ, Sherman WR, Hallcher LM, et al. Human<br />

diabetic endoneurial sorbitol, fructose and myo-inositol related<br />

to sural nerve morphometry. Ann Neurol; 8: 590-596, 1980<br />

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in the population of the Mureş county. Primul Congres<br />

Naţional al Asociaţiei Române pentru Studiul<br />

Obezităţii, Cluj-Napoca; 18-20 octombrie, 2001<br />

6. Consensus Statement. Treatment of Hypertension in<br />

Diabetes. Diabetes Care16, 10: 1394-1401, 1993<br />

7. 27. World Health Organization-International Society of<br />

Hypertension. Guidelines for the Management of<br />

Hypertension. Journal of Hypertension 17: 151-183,<br />

1999<br />

8. The EURODIAB Prospective Complications Study<br />

(PCS) Group: Cardiovascular risk factors predict diabetic<br />

peripheral neuropathy in type 1 subjects in Europe.<br />

Diabetologia 42:A50–A181, 1999<br />

9. Maser RE, Steenkiste AR, Dorman JS et al.<br />

Epidemiological correlates of diabetic neuropathy: report from<br />

Pittsburg Epidemiology of Diabetes Complications Study.<br />

Diabetes; 38; 1456-1461, 1989<br />

10. 31. Feldman EL. Oxidative stress and diabetic neuropathy:<br />

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431-433, 2003<br />

11. Haffner SM. Dyslipidemia management in adults with<br />

diabetes. Diabetes Care; 27: Suppl 1: S68-S71, 2004<br />

271

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