2018 чб тп +5 мм
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16<br />
ПРАКТИЧЕСКАЯ МЕДИЦИНА<br />
‘1 (112) март <strong>2018</strong> г.<br />
Heart rate variability in patients with heart failure<br />
combined with chronic obstructive pulmonary disease<br />
Contact:<br />
Gazizyanova V.M. — post-graduate student of the Department of Propedeutics of Internal Diseases, tel. +7-927-037-73-41,<br />
e-mail: violettakoshka2006@rambler.ru<br />
Bulashova O.V. — D. Med. Sc., Professor of the Department of Propedeutics of Internal Diseases, tel. (843) 296-14-03,<br />
e-mail: boulashova@yandex.ru<br />
Khazova E.V. — Cand. Med. Sc., Associate Professor of the Department of Propedeutics of Internal Diseases, tel. (843) 236-04-61,<br />
e-mail: hazova_elena@mail.ru<br />
Malkova M.I. — Cand. Med. Sc., Assistant Lecturer of the department of Propedeutics of Internal Diseases, Head of the Functional Diagnostics<br />
Department, tel. +7-960-051-61-16, e-mail: marimalk@yandex.ru<br />
The issues of comorbid pathology are of interest for many researchers due to the high prevalence, infavorable course<br />
and prognosis. One of the most common combinations in clinical practice is heart failure and chronic obstructive pulmonary<br />
disease. There are data of the presence of common risk factors and pathogenesis links, one of which is the neurohormonal<br />
disbalance. The research objective is to assess the heart rate variability in patients with chronic heart failure combined with<br />
chronic obstructive pulmonary disease in terms of clinical and functional characteristics. Materials and methods. 183 chronic<br />
heart failure patients of I-IV functional class (FC) were selected, including 105 patients with chronic obstructive pulmonary<br />
disease. All patients underwent spirometry and holter monitoring of the electrocardiogram. Results. The group of CHF patients<br />
with concomitant COPD is characterized by a decrease in the standard deviation of normal RR intervals - SDNN (p = 0.031),<br />
SDNN index (p = 0.005), an increase in the mean heart rate (p = 0.001), compared to the patients without pulmonary pathology.<br />
It was shown that with the progression of CHF (increase in the FC of CHF and a decrease in the left ventricular ejection<br />
fraction), SDNN values decrease (p
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