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Escleroterapia en sangrado digestivo alto por úlcera péptica Estudio ...

Escleroterapia en sangrado digestivo alto por úlcera péptica Estudio ...

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<strong>Escleroterapia</strong> digestiva<br />

desde el punto de vista de solidez<br />

de la evid<strong>en</strong>cia, no deja de<br />

a<strong>por</strong>tar conocimi<strong>en</strong>tos y experi<strong>en</strong>cias<br />

para permitirnos sugerir<br />

y recom<strong>en</strong>dar que <strong>en</strong> nuestro<br />

medio la maniobra diagnóstica<br />

y terapéutica, ideal y económica<br />

<strong>en</strong> el abordaje de un <strong>en</strong>fermo<br />

con hemorragia digestiva alta es<br />

la realización de una <strong>en</strong>doscopia<br />

digestiva alta con el equipo adecuado<br />

para realizar una sesión<br />

eficaz de escleroterapia que permita<br />

det<strong>en</strong>er el <strong>sangrado</strong> y así<br />

continuar ofreci<strong>en</strong>do el mejor<br />

tratami<strong>en</strong>to a nuestros <strong>en</strong>fermos,<br />

que <strong>en</strong> el caso de la hemorragia<br />

digestiva no es farmacológico,<br />

sino mecánico.<br />

Summary<br />

Curr<strong>en</strong>tly, therapeutic <strong>en</strong>doscopy<br />

has changed the treatm<strong>en</strong>t of<br />

gastrointestinal bleeding caused<br />

by peptic ulcer. This trial has<br />

be<strong>en</strong> designed to prove the effectiv<strong>en</strong>ess<br />

of injection therapy<br />

using sclerosing ag<strong>en</strong>ts in upper<br />

gastrointestinal tract bleeding.<br />

We outlined a controlled study,<br />

using historical controls; each<br />

group consisted of 96 pati<strong>en</strong>ts.<br />

Treated pati<strong>en</strong>ts received an<br />

adr<strong>en</strong>aline and alcohol solution;<br />

96% of pati<strong>en</strong>ts treated by<br />

<strong>en</strong>doscopy injection revealed<br />

healing, in comparison to 77%<br />

in the control group. Treatm<strong>en</strong>t<br />

response of upper gastrointestinal<br />

bleeding caused by peptic<br />

ulcer is better wh<strong>en</strong> sclerosing<br />

ag<strong>en</strong>ts are used.<br />

Refer<strong>en</strong>cias<br />

1. Freeman ML. Endoscopic Control of ulcerbleeding.<br />

Sem Gastrointest Dis 1992; 3:<br />

65-74.<br />

2. Ruzkowski Ch J, Sanowski R. Injection<br />

theraphy for hemostasis of Bleeding Peptic<br />

Ulcers; Techniques and results of randomized<br />

prospectives trials. Clin North Amer<br />

Gastrointest Endosc 1991; 1(2): 303-318.<br />

3. Otari T, Tatzuka T, et al. Intramural injection<br />

of ethanol under direct vision of the<br />

treatm<strong>en</strong>t of protuberant lesions of the stomach.<br />

Gastro<strong>en</strong>terol 1975; 69: 123-126.<br />

4. Soeh<strong>en</strong>dra W, Werner B. New techniques<br />

for <strong>en</strong>doscopic treatm<strong>en</strong>t of bleeding gastric<br />

ulcer. Endoscopy 1976; 8: 85-90.<br />

5. Soeh<strong>en</strong>dra W, Grimm H, et al. Injection of<br />

nonvariceal lesions of the upper gastrointestinal<br />

tract. Endoscopy 1985; 17: 129-132.<br />

6. Asaki S, Nishimura T, et al. Endoscopic<br />

control of gastrointestinal hemorrhage by<br />

local injection of absolute ethanol: A basic<br />

assessm<strong>en</strong>t of the procedure. Tohoku JExp<br />

Med 1983;140:339-341.<br />

7. Ch<strong>en</strong> PC, Wu CS, Liaw YG. Hemostatic<br />

effect of <strong>en</strong>doscopic local injection with hypertonic<br />

saline-epinephrine solution and pure<br />

ethanol for digestive tract bleeding. Gastrointest<br />

Endosc 1986; 32: 319-324.<br />

8. De Felice C. Endoscopic injection treatm<strong>en</strong>t<br />

in paci<strong>en</strong>ts with shock and gastrointestinal<br />

bleeding or stigmata of rec<strong>en</strong>t hemorrhage.<br />

Endoscopy 1987; 19: 1985-1989.<br />

9. Sugawa C, Fukita Y, et al. Endoscopic<br />

hemostasis of bleeding of the upper gastrointestinal<br />

tract by local injection of ninetyeight<br />

perc<strong>en</strong>t deshydrated ethanol. Surg<br />

Gynecol Obstet 1986; 162: 159-162.<br />

10. Panes J, Forne M, et al. Controlled trial of<br />

<strong>en</strong>doscopic esclerosis in bleeding peptic<br />

ulcers. Lancet 1987; 2: 1292-1295.<br />

11. C h u n g S C , L e u n g J W e t a l.Endoscopic<br />

injection of adr<strong>en</strong>aline for actively bleeding<br />

ulcers; a randomized controlled study.<br />

Br Med 1988:296: 1631-1635.<br />

12. W o o d s A, Sanowskira, et al. Endoscopic<br />

therapy of gastric and duod<strong>en</strong>al bleeding: a<br />

comparison of BICAP coagulation versus<br />

ethanol sclerotherapy. Gastrointest Endosc<br />

1988; 34: 209-213.<br />

13. L i n H J , L e e F , e t al. Heat probe thermocoagulation<br />

and pure alcohol injection in<br />

massive peptic ulcer hemorrhage: A prospective,<br />

randomized controlled trial. Gut<br />

1990; 31: 753-755.<br />

14. L a i n e L . Multipolar electrocoagulation<br />

versus injection therapy in the treatm<strong>en</strong>t of<br />

bleeding peptic ulcers. A prospective randomized<br />

trial. Gastro<strong>en</strong>terol 1990;<br />

99:1303-1305.<br />

15. B a l a n z o J, S a i n z S, et al. Endoscopic<br />

hemostasis by local injection of epinephrine<br />

and polidocanol in bleeding ulcer. A<br />

prospective randomized trial. Endoscopy<br />

1988; 20: 289-292.<br />

16. B o i x J , P l a n a s R , e t a l . Endoscopic<br />

hemostasis by injection therapy and<br />

electrohydro-coagulation in high-risk pati<strong>en</strong>ts<br />

with active gastroduod<strong>en</strong>al bleeding<br />

ulcer. Endoscopy 1987; 19: 225-227.<br />

17. P a n e s J , B o r n e M, et al. Endoscopic sclerosis<br />

in the treatm<strong>en</strong>t of bleeding pepticulcers<br />

with a visible vessel. Am J<br />

Gastro<strong>en</strong>terol 1990 85: 252-255.<br />

18. R u t g e e r t s P, B r o e c h a e r t H, e t a l.Comparison<br />

of <strong>en</strong>doscopic polidocanol injection<br />

and YAG laser theraphy for bleeding<br />

peptic ulcers. Lancet 1989; 1: 1164-1166.<br />

19. B a l a n z o C, Villanueva S, et al. Injection<br />

theraphy of bleeding peptic ulcer. A prospective<br />

randomized trial using epinephrine<br />

and thrombin. Endoscopy 1990; 8:<br />

157-160.<br />

20. Weisz W, J<strong>en</strong>s<strong>en</strong> DM. Improved strategies<br />

for managing upper GI bleeding.<br />

Contemp Intern Med 1990; 2: 42-43.<br />

21. Chung SC, Leung JW, et al. Injection or<br />

heat probe for bleeding ulcers. Gastro<strong>en</strong>terol<br />

1991; 100: 33-36.<br />

Acta Med Colomb Vol. 20 N° 5 ~ 1995 227

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