23.02.2016 Views

netupitantpalonosetrón

IPT-netupitant-palonosetron-akynzeo

IPT-netupitant-palonosetron-akynzeo

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

9. NCCN Clinical Practice Guidelines in Oncology (NCCN<br />

Guidelines®). NCCN guidelines for supportive care.<br />

Antiemesis. Disponible en:<br />

http://www.nccn.org/professionals/physician_gls/f_guidelines_n<br />

ojava.asp#supportive. Última actualización 27 de septiembre de<br />

2015.<br />

10. Eisenberg P, MacKintosh FR, Ritch P, et al. Efficacy, safety,<br />

and pharmacokinetics of palonosetron in patients receiving<br />

highly emetogenic, cisplatin-based chemotherapy: a doseranging,<br />

clinica study. Ann Oncol. 2004; 15:330–7.<br />

11. Rojas C, Thomas AG, Alt J, et al. Palonosetron triggers 5-HT3<br />

receptor internalization and causes prolonged inhibition of<br />

receptor function. J Pharmacol. 2010; 626:193–9.<br />

12. Hesketh PJ, Rossi G, Rizzi G et al. Efficacy and safety of<br />

NEPA, an oral combination of netupitant and palonosetron, for<br />

prevention of chemotherapy-induced nausea and vomiting<br />

following highly emetogenic chemotherapy: a randomized dose<br />

ranging pivotal study. Ann Oncol 2014; 25: 1340–1346.<br />

13. Aapro M, Rugo H, Rossi G et al. A randomized phase III study<br />

evaluating the efficacy and safety of NEPA, a fixed-dose<br />

combination of netupitant and palonosetron, for prevention of<br />

chemotherapy-induced nausea and vomiting following<br />

moderately emetogenic chemotherapy. Ann Oncol 2014; 25:<br />

1328–1333.<br />

14. Gralla RJ, Bosnjak SM, Hontsa A et al. A phase III study<br />

evaluating the safety and efficacy of NEPA, a fixed-dose<br />

combination of netupitant and palonosetron, for prevention of<br />

chemotherapy-induced nausea and vomiting over repeated<br />

cycles of chemotherapy. Ann Oncol 2014; 25: 1333–1339.<br />

15. EPAR de netupitant. Disponible en:<br />

http://www.ema.europa.eu/docs/en_GB/document_library/EPA<br />

R_-_Product_Information/human/003728/WC500188432.pdf.<br />

Último acceso: 17 de julio de 2015.<br />

16. Eisenberg P1, Figueroa-Vadillo J, Zamora R, Charu V,<br />

Hajdenberg J, Cartmell A, Macciocchi A, Grunberg S; 99-04<br />

Palonosetrón Study Group. Improved prevention of moderately<br />

emetogenic chemotherapy-induced nausea and vomiting with<br />

palonosetron, a pharmacologically novel 5-HT3 receptor<br />

antagonist: results of a phase III, single-dose trial versus<br />

dolasetron. Cancer. 2003 Dec 1; 98(11):2473-82.<br />

17. Gralla R, Lichinitser M, Van Der Vegt S, Sleeboom H, Mezger<br />

J, Peschel C, Tonini G, Labianca R, Macciocchi A, Aapro M.<br />

Palonosetron improves prevention of chemotherapy-induced<br />

nausea and vomiting following moderately emetogenic<br />

chemotherapy: results of a double-blind randomized phase III<br />

trial comparing single doses of palonosetrón with ondansetron.<br />

Ann Oncol. 2003 Oct; 14(10):1570-7.<br />

18. Aapro MS, Grunberg SM, Manikhas GM, Olivares G,<br />

Suarez T,Tjulandin SA, Bertoli LF, Yunus F, Morrica B,<br />

Lordick F, Macciocchi A. A phase III, double-blind,<br />

randomized trial of palonosetron compared with<br />

ondansetron in preventingchemotherapy-induced nausea<br />

and vomiting following highly emetogenic chemotherapy.<br />

Ann Oncol. 2006 Sep; 17(9):1441-9.<br />

19. Saito M, Aogi K, Sekine I, Yoshizawa H, Yanagita Y, Sakai H,<br />

Inoue K, Kitagawa C, Ogura T, Mitsuhashi S. Palonosetrón plus<br />

dexamethasone versus granisetron plus dexamethasone for<br />

prevention of nausea and vomiting during chemotherapy: a<br />

double-blind, double-dummy, randomised, comparative phase<br />

III trial. Lancet Oncol. 2009 Feb; 10(2):115-24.<br />

20. Hu, W.P.,You X.H.,Guan B.C.,Ru L.Q.,Chen J.G.,Li Z.W.<br />

SubstanceP potentiates 5-HT3 receptor-mediated current in rat<br />

trigeminal ganglion neurons. Neurosci.Lett. 2004; 365,147–152.<br />

21. Minami M, Endo T, Yokota H, Ogawa T, Nemoto M, Hamaue<br />

N, Hirafuji M, Yoshioka M, Nagahisa A. Andrews,P.L.Effects<br />

of CP-99,994, a tachykininNK(1)receptor antagonist, on<br />

abdominal afferent vagal activity in ferrets: evidence for in<br />

volvement of NK(1) and 5-HT(3) receptors.Eur.J.<br />

Pharmacol.2001; 428,215–220.<br />

22. Stathis M.,Pietra C.,Rojas C.,Slusher B.S.Inhibition of<br />

substance P- mediated responses in NG108-15 cells by<br />

netupitant and palonosetrón exhibit synergistic<br />

effects.Eur.J.Pharmacol.2012;689,25–30.<br />

23. Darmani N.A.,Chebolu S.,Amos B.,Alkam T.Synergistic antiemetic<br />

interactions between serotonergic 5-HT(3) and tachykininergic<br />

NK(1)-receptor antagonists in the least shrew<br />

(Cryptotisparva).Pharmacol.Biochem.Behav.2011;99, 573–579.<br />

24. Yavas C, Dogan U, Yavas G, Araz M, Ata OY. Acute effect of<br />

palonosetrón on electrocardiographic parameters in cancer<br />

patients: a prospective study. Support Care Cancer. 2012;<br />

20(10):2343–2347.<br />

25. Dogan U, Yavas G, Tekinalp M, Yavas C, Ata OY, Ozdemir K.<br />

Evaluation of the acute effect of palonosetron on transmural<br />

dispersion of myocardial repolarization. Eur Rev Med<br />

Pharmacol Sci. 2012; 16(4):462–468.<br />

26. Boyer EW, Shanon M. The serotonin syndrome. N Engl J<br />

Med.2005; 352:1112–20.<br />

Página 4 de 5

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!