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OXYGENE ET ACCIDENTS DE DÉSATURATION

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Augmentation de la VO 2 et<br />

restauration des fonctions<br />

mitochondriales 1<br />

Amélioration lioration du CMRO 2; ; de la<br />

microdialyse Lactate/pyruvate<br />

lors de la quand la PO 2 cérébrale brale<br />

est > à 200mmHg 2<br />

Am<br />

Hyperoxie et métabolisme<br />

m tabolisme énerg nergétique tique<br />

1 Daugherty WP, et al. Effects of hyperbaric oxygen therapy on cerebral<br />

oxygenation and mitochondrial function following moderate lateral fluidpercussion<br />

injury in rats.<br />

J Neurosurg – 2004.<br />

2 ROCKSWOLD SN, et al. A prospective, randomized clinical trial to<br />

compare the effect of hyperbaric to normobaric hyperoxia on cerebral<br />

metabolism, intracranial pressure, and oxygen toxicity in severe<br />

traumatic brain injury<br />

J Neurosurg - 2010.

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