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Thibault AcMo DIU 2009-10 - ASSIM

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Plan<br />

• Structure des immunoglobulines (Ig)<br />

• <strong>AcMo</strong> murins<br />

– Production d’hybridomes<br />

– Limites de leur utilisation<br />

• <strong>AcMo</strong> humanisés et humains<br />

– Ac chimériques<br />

– Ac humanisés<br />

– Ac fully human<br />

• Mécanismes d’action<br />

Gilles <strong>Thibault</strong>, 07-01-20<strong>10</strong>

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