Chemical constituents of g. benthamii

Chemical Constituents of Garcinia benthami Pierre
Consolacion y. Ragasa, Jasmine Ting*, Romeo Lerom and Chien-Chang Shen
Institution: De La Salle University
Adviser: Consolacion y Ragasa
Undergraduate: 2013-2016
Graduate studies: (MSc) 2016-2018, (PhD) 2019-present
Abstract: Garcinia benthami Pierre (syn Garcinia ferrea Pierre) is also known as Bunog by
the Cuyunin tribe and Tagbanua in Palawan Philippines. The compounds present in the
dichloromethane (DCM) extract of roots, fruit peels, fruit seeds, fruit fleshes, stem barks,
leaves and flowers were isolated by using normal phase chromatography and identified by
NMR spectroscopic technique. Triacylglycerol (TAG) was isolated in extract of roots, stem
barks, flesh and seed of the fruits. Squalene was isolated from roots, fruit peels, stem barks
and fruit fleshes extract. Caryophyllene (CAR) was isolated from fruit peels and leaves extract.
Methyl (24E)-3 α ,9 α , 23-trihydroxy-17,14-friedolanosta-14,24-dien-26-oate was isolated
from fruit peels, leaves and flowers extract. While the mixture of β -sitosterol and

stigmasterol was obtained from flowers and fruit seeds extract. Chlorophyll a and α –
carotene were only isolated from the leaves and friedelin was only isolated from stem barks
extract. A new triterpene (24E)-23 acetoxy-3α-hydroxylanostane-9(11), 16, 24-trien-26-oic
acid were isolated from the roots extract and obtained as part of the mixture with (22Z, 24E)-
9 α -hydroxy-3-oxo-17,14-friedolanosta-14,22-24-trien-26-oic acid and a new triterpene
(24E)-9 α -hydroxy-3-oxo-17,14-friedolanosta-14, 24-dien-26-oic acid from the fruit peels
extract. Another mixture of triterpenes, (22Z, 24E)-9α-hydroxy-3-oxo-17,14-friedolanosta-
14,22-24-trien-26-oic acid and Methyl (24E)-9,23-dihydroxy-3-oxo-17,14-friedolanostan-
14,24-dien-26-oate (another new triterpene) was obtained from the stem barks.