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MoNDaY, jUlY 26, 2021

5

Covid-19 boosted excess sale

of antibiotics in India

an inmate at the Central Prison in Freetown, Sierra leone. Photo: anne-Sophie Faivre le Cadre

Sierra Leone abolishes

capital punishment

SaeeD KaMalI DehGhaN

Sierra Leone has become the latest

African state to abolish the death

penalty after MPs voted unanimously to

abandon the punishment. On Friday

the west African state became the 23rd

country on the continent to end capital

punishment, which is largely a legacy of

colonial legal codes. In April, Malawi

ruled that the death penalty was

unconstitutional, while Chad abolished

it in 2020. In 2019, the African human

rights court ruled that mandatory

imposition of the death penalty by

Tanzania was "patently unfair".

Of those countries that retain the

death penalty on their statute books, 17

are abolitionist in practice, according to

Amnesty International. A de facto

moratorium on the use of the death

penalty has existed in Sierra Leone

since 1998, after the country

controversially executed 24 soldiers for

their alleged involvement in a coup

attempt the year before.

Under Sierra Leone's 1991

constitution, the death penalty could be

prescribed for murder, aggravated

robbery, mutiny and treason. Last year,

Sierra Leone handed down 39 death

sentences, compared with 21 in 2019,

according to Amnesty, and 94 people

were on death row in the country at the

end of last year.

Rhiannon Davis, director of the

women's rights group AdvocAid, said:

"It's a huge step forward for this

fundamental human right in Sierra

Leone. "This government, and previous

governments, haven't chosen to [put

convicts to death since 1998], but the

next government might have taken a

different view," she said.

"They [prisoners] spend their life on

death row, which in effect is a form of

torture as you have been given a death

sentence that will not be carried out

because of the moratorium, but you

constantly have this threat over you as

there's nothing in law to stop that

sentence being carried out."

Davis said the abolition would be

particularly beneficial to women and

girls accused of murdering an abuser.

"Previously, the death penalty was

mandatory in Sierra Leone, meaning a

judge could not take into account any

mitigating circumstances, such as

gender-based violence," she said.

Umaru Napoleon Koroma, deputy

minister of justice, who has been

involved in the abolition efforts, said

sentencing people on death row to "life

imprisonment with the possibility of

them reforming is the way to go".

Across sub-Saharan Africa last year

Amnesty researchers recorded a 36%

drop in executions compared with 2019

- from 25 to 16. Executions were carried

out in Botswana, Somalia and South

Sudan.

SaNjeet BaGCChI

The first wave of COVID-19 in 2020 in

India saw a substantial increase in the

sale of antibiotic formulations used in

adults and adolescents, especially

azithromycin, says a study. COVID-19

likely contributed to about 216 million

excess doses of non-paediatric

formulations of antibiotics in total and

38 million excess doses of azithromycin

between June and September 2020,

says the study published this month in

PLOS Medicine, which looked at the

private health care sector in India.

Antibiotics are often used in viral

infections, such as viral pneumonia, to

combat possible bacterial co-infections.

This is despite antibiotics being

ineffective against viral infections,

according to the US Centers for Disease

Control and Prevention.

Overall, 16.29 million doses of

antibiotics were sold in India, the

world's largest antibiotic user. The

proportion of non-paediatric

formulations of antibiotics increased

from 72.5 per cent in 2019 to 76.8 per

cent in December 2020, with children

less likely to suffer from symptomatic

and severe COVID-19 infection,

researchers noted.

Sumanth Gandra, study author and

associate professor of the Division of

Infectious Diseases, Washington

University School of Medicine, US, tells

SciDev.Net that the results suggest that

nearly every person diagnosed with

COVID-19 received an antibiotic - most

especially azithromycin - during the

first wave in India.

"Our results indicate that at least 12

million azithromycin treatment

courses were unnecessarily prescribed

between June and December of 2020,"

says Gandra. "This massive use of

azithromycin, a vital drug for treating

typhoid fever and diarrhoea, is highly

concerning as it will lead to resistance

in bacteria that cause these illnesses."

According to Brian Godman, a

visiting professor at the Strathclyde

Institute of Pharmacy and Biomedical

Sciences, UK, it is important to curb

inappropriate use of antibiotics for viral

infections which will increase

resistance rates and result in greater

loss of life in the future.

"This is particularly important in the

community since inappropriate

prescribing and dispensing of

antimicrobials for essentially viral

infections constitutes their greatest

overuse," Godman tells SciDev.Net.

"Trained pharmacists are important as

they can direct patients to more

appropriate treatments that are more

effective in symptomatic relief and

often cheaper. This should be a priority

in India given the rising antimicrobial

resistance rates."

Similar trends are likely to have

occurred in other low- and middleincome

countries where antibiotics are

often overused, the study said. The

medium- and long-term consequences

for bacterial resistance patterns are

"highly concerning", it added,

highlighting the need for urgent

antibiotic stewardship measures such

as avoiding the use of antibiotics if

there is no suspicion of bacterial

infection, and limiting the duration of

antibiotic treatment for co-infections.

India's approach to antibiotic use

during the pandemic was more of a

knee-jerk reaction than a well thoughtout

plan, says Diptendra Sarkar, a

COVID-19 strategist, public health

analyst and professor at the Institute of

Post Graduate Medical Education and

Research, Kolkata, India.

"While evolving evidence did not

favour the use of antibiotics, there was

little governance on the community use

of antibiotics," Sarkar tells SciDev.Net.

"Self-medication also played a major

role in upscaling antibiotic use that are

not evidence-based."

Customers line up in front of a pharmacy in Kolkata.

Photo: Indrajit Das

Violence against Africa's children is rising

experts say that hIV digital toolkits have to be simple, affordable and adaptable, while ensuring

absolute confidentiality.

Photo: Keila trejo

Digital toolkit to fight HIV disease

eStheR NaKKazI

Digital tools widening access to HIV

prevention, treatment and care

services will be a vital weapon in the

fight against the disease during

COVID-19 and beyond - but they

must be affordable and highly

confidential.

So said health experts at the 2021

International AIDS Society

conference held remotely from Berlin

this week. The event looked at the

potential of digital technology in

eradicating HIV and AIDS, which

currently affects around 38 million

people worldwide.

The Industry Liaison Forum (ILF)

of the International AIDS Society

(IAS) identified and prioritised a set

of digital technological innovations,

based on advances made during the

COVID-19 pandemic, which they say

should be adopted for HIV

prevention and care and to shape

digital health more broadly.

Pradeep Kakkattil, director of the

office of innovations at UNAIDS,

said: "The AIDS movement has been

very much about being the

conscience of access to health and

equity. We need to continue to play

that role when it comes to this

transition from where we are in the

shift to digital, as we digitise health

and access to healthcare."

The digital toolkit includes mobile

applications like SMS that simplify

the return of medical results,

telemedicine which enables online

drug ordering for home delivery, and

public data repositories.

The IAS says it will also look beyond

HIV to how emerging health

technologies have the potential to

improve global health equity and

drive progress towards the

Sustainable Development Goals.

In the session led Wednesday by

the IAS-ILF and UNAIDS, which

oversees the Health Innovation

Exchange (HIEx), panellists agreed

that digital tools must be simple,

adaptable, and affordable, and

designed with local engagement to

ensure absolute confidentiality.

"What we have seen with the

COVID-19 response is that it has been

very much top-down, with no

engagement of communities," said

Helen McDowell, head of

government affairs and global public

health in the UK and a recently

elected ILF industry representative.

"We have also seen the exploitation in

terms of when it comes to profit -

profit versus lives.

"We really need to have this

bottom-up approach which is

community-led … to ensure that we

have equity in terms of access and

trust which is a basic foundation in

the digitisation process." Rahab

Mwaniki, a public health specialist

based in Kenya, said: "In order for

communities not to be left behind we

need to ensure affordability and

confidentiality because some people

have not disclosed their status. We

also need tools that are cost effective."

For McDowell, the solution is

"partnership and collaboration".

"These have to exist between the

industry, public private partnerships,

government and the community,"

she said.

Meg Davis, a senior researcher on

the digital health and rights project at

the Graduate Institute in Geneva,

said: "We need to know which

platforms people are using, how are

they engaging with them … who

really is pushing these platforms to

ensure that people are accessing

information safely and securely."

People with HIV must be engaged

in the design process from the

beginning, says Mwanika, and

remunerated for their participation.

"There is a tendency to look at

communities as people who can just

give their services for free," she

added. "I think if a product is forprofit,

they also need to facilitate the

process for the community."

Nick Hellmann, managing director

and strategy and science advisor at

the Elizabeth Glaser Pediatric AIDS

Foundation, said: "It really does take

a village to implement all these

things. If the community is engaged

very early on in the development

process, you can start to address not

only the issues of scalability, but also

some of the confidentiality and

privacy issues because then everyone

comes out on the same page."

GRaça MaChel

Of all the unspeakable injustices

suffered by Africa's children - and I've

witnessed many - violence is surely the

worst because it is almost entirely

preventable. Africa's children suffer

many hardships, including poverty,

hunger and disease. Violence against

children is avoidable, yet young people

in Africa, especially girls, continue to

live with sexual violence, child

marriage, female genital mutilation,

forced labour, corporal punishment and

countless other forms of abuse.

After decades spent trying to improve

young people's life chances, I had hoped

to see at the very least a significant

reduction in violence that threatens

children. It is now 31 years since the

adoption of the African Charter on the

Rights and Welfare of the Child and we

have seen some governments putting

into place laws and policies aimed at

ending violence against children. There

have also been efforts, though

insufficient, towards eradicating female

genital mutilation and child marriage,

which cause untold lifelong suffering.

Progress is uneven, fragmented and

slow. Violence against children is once

more on the rise driven partly by online

sexual exploitation and child sexual

abuse tourism and recently by

lockdowns and school closures. These

have pushed violence behind closed

doors where it goes unseen and

unreported. Armed conflicts by groups

such as Boko Haram in Nigeria, al-

Shabaab in Somalia and Amba

separatists in Cameroon, frequently

target children, making them the most

common victims of abductions, rape,

forced marriages and murder.

Regrettably, many African

governments lack the political will to

tackle these gross violations. This week,

in an attempt to galvanise action, the

African Partnership to End Violence

against Children (Apevac) convened a

high-level virtual conference to present

its new research findings confirming

worrying levels of violence and slow

government responses. Thankfully,

there are also some good, African

solutions that can be successfully

applied across the continent.

I have witnessed the worst, as well as

the best, of humanity. Yet the brutality

revealed in these findings plumb new

depths. Children still face unacceptable

levels and forms of physical,

psychological and sexual violence. In

some parts of Africa, four in 10 girls

suffer sexual violence before the age of

15. Even worse is that children in most

need - those in residential care or used

as child labour, with disabilities, living

on the streets, or in armed conflict and

refugee situations - are not protected.

Violence against children is not a

uniquely African phenomenon. The

World Health Organization estimated

last year that globally up to a billion

children aged 2-17 had experienced

physical, sexual or emotional violence

or neglect. Many African children enjoy

peaceful lives, but it is clear the

continent faces an urgent problem,

fuelled by complex social and economic

drivers. Increasing urbanisation, armed

conflict, forced displacement,

humanitarian and climate-related

disasters all play a part.

Children surround a UN soldier patrolling a camp for internally displaced people in Goma, in the

Democratic Republic of the Congo.

Photo: Pascal Guyot

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