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Corelatii intre hemoleucograma automata si frotiul ... - Despre ALMR

Corelatii intre hemoleucograma automata si frotiul ... - Despre ALMR

Corelatii intre hemoleucograma automata si frotiul ... - Despre ALMR

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Mecanism de aparitie<br />

<strong>Corelatii</strong> <strong>intre</strong> <strong>hemoleucograma</strong> <strong>automata</strong> <strong>si</strong> <strong>frotiul</strong> de sange periferic. Bucuresti, 1 oct 2011<br />

Pseudotrombocitopenia indusa de EDTA<br />

• in prezenta EDTA, in membrana plachetara se expune <strong>si</strong>tusul de legare a atg din<br />

complexul GP IIb/IIIa<br />

• EDTA modifica atg din membrana plachetara → legarea atc antifosfolipidici<br />

antiplachetari<br />

• Nu este insotita de anomalii plachetare functionale (agregabilitate normala)<br />

• Nu este insotita de semne/<strong>si</strong>mptome hemoragice<br />

• apare in cateva minute dupa contactul sangelui cu EDTA<br />

• este mai evidenta in probele tinute la t°camerei

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