DÉBORA MARIA MARQUIORI MARQUES INTOXICAÇÃO ...

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ABSTRACT The aim of this study was to determine the toxicity of Cestrum laevigatum for buffalos and characterize the clinical and pathological intoxication. Were used four Murrah buffaloes divided into two groups. Group 1 (buffalo 1 and 2) received 20g/kg of dried leaves of Cestrum laevigatum fed orally, whereas group 2 (buffalo 3 and 4) received 40g/kg. Buffalo 1 (group 1) showed mild clinical signs, characterized by a reduction of ruminal movements and recovered 60 hours after onset of clinical symptoms. Buffalo 2 (group 1) showed no signs. Buffaloes 3 and 4 (Group 2) showed the first signs 26h05min and 37h22min after the end of the administration, respectively. Clinical signs of intoxication were lethargy, anorexia, decrease or absence of ruminal movements, drooling, difficulty breathing, staggering gait, dysmetria, excitement, aggression, constipation, with stools containing mucus and blood, groans, dry nose, drowsiness, paddling movements and death in 44h11min (buffalo 3) and 60h39min (buffalo 4) after administration of the plant. At necropsy, Buffalo 3 revealed capsular and cut surface of liver brownish orange, mild edema of the gallbladder wall, left ventricular endocardium with extensive haematomas and endocardium of the right ventricle with a few petechiae, abomasum mucosa slightly reddish; contents abomasum slightly dry, large intestine with little content slightly dry and surrounded by mucus. In Buffalo 4 capsular and cut surface of liver colored orange, with a clear aspect of nutmeg , mild edema of gallbladder wall, mild splenomegaly, slightly reddish mucosa of the abomasum, small intestine content catarrhal and mucous, and slightly congested meninges. Histologically, the liver of both animals demonstrated marked coagulation and necrosis of hepatocytes in central and intermediate lobular zones and vacuolization of hepatocytes close to the areas of necrosis. Key-words: Plant poisoning. Cestrum laevigatum. Solanaceae. buffalo
LISTA DE FIGURAS Figura 1 –Distribuição geográfica do Cestrum laevigatum no Brasil......................13 Figura 2 – Cestrum laevigatum em seu habitat .......................................................15 Figura 4 – Intoxicação por C. laevigatum, búfalo 4. Fígado. Fígado fixado com aspecto de noz moscada na superfície de corte ......................................................34
Page 1 and 2: DÉBORA MARIA MARQUIORI MARQUES INT
Page 4 and 5: A minha Mãe, que nunca deixou de a
Page 6 and 7: “Mesmo se eu andar por um vale de
Page 10 and 11: LISTA DE ABREVIATURAS RJ - Rio de J
Page 12 and 13: 1. INTRODUÇÃO Plantas tóxicas co
Page 14 and 15: 2. REVISÃO DE LITERATURA ATURA 2.1
Page 16 and 17: observando-se, também, tremores mu
Page 18 and 19: vermelho escuro e marron-amarelado,
Page 20 and 21: ingerida, como fome, carência de f
Page 22 and 23: alguns minutos com a cabeça encost
Page 24 and 25: Os sinais clínicos observados nos
Page 26 and 27: última se expandiu rapidamente e n
Page 28 and 29: esistentes do que os bovinos. A pla
Page 30 and 31: sobre sua importância como planta
Page 32 and 33: foram enviadas para o Laboratório
Page 34 and 35: do cólon e do reto estava levement
Page 36 and 37: Os exames histopatológicos revelar
Page 38 and 39: 6. CONCLUSÕES Bubalinos são sens
Page 40 and 41: DÖBEREINER J; TOKARNIA, C. H; CANE
Page 42 and 43: MÉNDEZ M.C. Intoxicação por Echi
Page 44: THRALL M.A; BAKER C.D; CAMPBELL T.W

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