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Pertino M, Schmeda-Hirschmann G, Santos LS, Rodríguez<br />
JA, Theoduloz C. Biotransformation of jatrophone by Aspergillus<br />
niger ATCC 16404. Zeitschrift Fur Naturforschung Section B-<br />
A Journal of Chemical Sciences. 62: 275-279, 2007.<br />
Pertino M, Schmeda-Hirschmann G, Rodríguez J A, Theoduloz<br />
C. Gastroprotective effect and cytotoxicity of terpenes from<br />
the Paraguayan cru<strong>de</strong> drug yagua rova (Jatropha isabelli). Journal<br />
of Ethnopharmacology. 111: 553-559, 2007.<br />
Pertino M, Schmeda-Hirschmann G, Rodríguez JA, Theoduloz<br />
C. Gastroprotective effect and cytotoxicity of semisynthetic<br />
jatropholone <strong>de</strong>rivatives. Planta Médica. 73: 1095-1100, 2007.<br />
Santos LS, Rosso GB, Pilli RA, Eberlin MN. The mechanism<br />
of the stille reaction investigated by electrospray ionization<br />
mass spectrometry. Journal of Organic Chemistry. 72: 5809-<br />
5812, 2007.<br />
Santos LS, Cunha RLOR, Comasseto JV, Eberlin MN. Electrospray<br />
ionization mass spectrometric characterization of key Te(IV)<br />
cationic intermediates for the addition of TeCl4 to alkynes .<br />
Rapid Communications In Mass Spectrometry. 21: 1479-1484,<br />
2007.<br />
Schmeda-Hirschmann G, Aranda C, Kurina M, Rodríguez JA,<br />
Theoduloz C. Biotransformations of imbricatolic acid by<br />
Aspergillus niger and Rhizopus nigricans cultures. Molecules. 12:<br />
1092-1100, 2007.<br />
Tapia A, Cheel J, Theoduloz C, Rodríguez JA, Schmeda-<br />
Hirschmann G, Gerth A, Wilken D, Jordan M, Jimenez-<br />
Gonzalez E, Gomez-Kosky R, Mendoza, EQ. Free radical<br />
scavengers from Cymbopogon citratus (DC.) Stapf plants cultivated<br />
in bioreactors by the temporary immersion (TIS) principle.<br />
Zeitschrift Fur Naturforschung C-A Journal of Biosciences.<br />
62: 447-457, 2007.<br />
2008<br />
Alarcón J, Astudillo L, Gutiérrez M. Inhibition of<br />
Acetylcholinesterase Activity by Dihydro-beta-agarofuran<br />
Sesquiterpenes Isolated from Chilean Celastraceae. Zeitschrift<br />
Fur Naturforschung Section C-A Journal of Biosciences. 63:<br />
853-856, 2008.<br />
Areche C, Theoduloz C, Yañez T, Souza-Brito A, Barbastefano<br />
V, De Paula D, Ferreira A.L, Schmeda-Hirschmann G, Rodríguez<br />
J A. Gastroprotective activity of ferruginol in mice and rats:<br />
effects on gastric secretion, endogenous prostaglandins and<br />
non-protein sulfhydryls. Journal of Pharmacy and Pharmacology.<br />
60: 245-251, 2008.<br />
Astudillo L, Vallejos G, Correa N, Gutiérrez M, De la Guarda<br />
W, Kouznetsov V. An Efficient Synthesis of 2, 3-Diaryl-2azabicyclooctanones<br />
Via BiCl3-Catalysed Three-Component<br />
aza Diels-Al<strong>de</strong>r Reaction. Letters in Organic Chemistry. 5:<br />
559-562, 2008.<br />
130 Memoria <strong>de</strong> <strong>Investigación</strong> 2007 y 2008<br />
Bispo <strong>de</strong> Jesus M, Zambuzzi W.F, Ruela <strong>de</strong> Sousa R.R, Areche<br />
C, Santos <strong>de</strong> Souza A C, Aoyama H, Schmeda-Hirschmann G,<br />
Rodríguez J A, <strong>de</strong> Souza Brito A R M, Peppelenbosch M P,<br />
Den Hertog J, De Paula E, Ferreira C V. Ferruginol suppresses<br />
survival signaling pathways in androgen-in<strong>de</strong>pen<strong>de</strong>nt human<br />
prostate cancer cells. Biochimie. 90: 843-854, 2008.<br />
Espinoza M, Santos L, Theoduloz C, Schmeda-Hirschmann G,<br />
Rodríguez J. New Gastroprotective Ferruginol Derivatives with<br />
Selective Cytotoxicity against Gastric Cancer Cells Planta<br />
Médica. 74: 802-80, 2008.<br />
Hauenstein E, Peña-Cortés F, Bertrán C, Tapia J, Schlatter<br />
R. Comparación Florística y Estado Trófico Basado en Plantas<br />
Indicadoras <strong>de</strong> Lagunas Costeras <strong>de</strong> la Región <strong>de</strong> La Araucanía.<br />
Ecología Austral. 18:43-53, 2008.<br />
Moore-Carrasco R, Aranguez-Arellano C, Razmilic I, Toloza L,<br />
Morales E, Argiles JM, Palomo I A high fat diet in CF-1 mice:<br />
An experimental mo<strong>de</strong>l for metabolic syndrome. Molecular<br />
Medicine Reports. 1: 401-405, 2008.<br />
San-Martín A, Rovirosa J, Astudillo L, Sepúlveda B, Ruiz D,<br />
San-Martín C. Biotransformation of the marine sesquiterpene<br />
pacifenol by a facultative marine fungus . Natural Product<br />
Research. 22: 1627-1632, 2008.<br />
Santos LS, Metzger JO. On-line monitoring of Brookhart<br />
polymerization by electrospray ionization mass spectrometry<br />
. Rapid Communications in Mass Spectrometry. 22: 898-904,<br />
2008.<br />
Santos LS. Online mechanistic investigations of catalyzed<br />
reactions by electrospray ionization mass spectrometry: A<br />
tool to intercept transient species in solution. European Journal<br />
of Organic Chemistry. 2: 235-253, 2008.<br />
Schmeda-Hirschmann G, Hormazabal E, Rodríguez JA,<br />
Theoduloz C. Cycloaspepti<strong>de</strong> A and pseurotin A from the<br />
endophytic fungus Penicillium janczewskii. Zeitschrift Fur<br />
Naturforschung Section C-A Journal of Biosciences. 63: 383-<br />
388, 2008.<br />
Schmeda-Hirschmann G, Tapia A, Lima B, Pertino M, Sortino<br />
M, Zacchino S, Rojas <strong>de</strong> Arias A, Feresin G.E. A new<br />
antimicrobial and antiprotozoal <strong>de</strong>psi<strong>de</strong> from the An<strong>de</strong>an<br />
lichen Protousnea poepigii. Phytotherapy Research. 22: 349-<br />
355, 2008<br />
Shankaraiah N, Da Silva W, Andra<strong>de</strong> C, Santos LS.<br />
Enantioselective total synthesis of (S)-(-)-quinolactacin B.<br />
Tetrahedron Letters. 49: 4289-4291, 2008.<br />
Shankaraiah N, Pilli R, Santos LS. Enantioselective Total Syntheses<br />
of Ropivacaine and its Analogues Tetrahedron Letters. 49:<br />
5098-5100, 2008.<br />
Val<strong>de</strong>rrama J, Leiva H, Rodríguez J, Theoduloz C, Schmeda-<br />
Hirschmann G. Studies on quinones. Part 43: Synthesis and