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ESTADO DE MAL EPILEPTICO - CTI

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VALPROATO<br />

Presentación: 1 ampolla = 500mg<br />

Carga: 25 - 60 mg/kg en 20 min<br />

No sedante ni hipotensor<br />

80% de efectividad<br />

Inhibidor del sistema P450<br />

Hiperamoniemia, pancreatitis, trombocitopenia<br />

Falla hepática rara<br />

Nivel serico: 150mcg/ml<br />

Uso concomitante de meropenem o amikacina<br />

disminuye niveles sericos<br />

Todos los tipos de crisis incluyendo mioclonias

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