2 - Infoset
2 - Infoset
2 - Infoset
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Adhésion à la bithérapie chez les<br />
usagers de drogues<br />
Revue de 16 études cliniques prospectives 2000-2008<br />
(953 pts, 78 % H, 96 % ttt substitution, 50% génotype1,4)<br />
Revue 16 études <br />
Contrôle (2 registraEon <br />
trials in non-‐IDU popul.) <br />
RVS 52 % (44%-‐60%, CI 95%)* 50% (39-‐61%, CI 95%) <br />
Drop out 26 % (18-‐35%, CI 95%) 26% (12-‐41%, CI 95%) <br />
ES psy sévères 2 % (1-‐3%, CI 95%) 2% (0-‐6%, CI 95%) <br />
* Génotype 2,3 : 66 %<br />
Génotype 1,4 : 44 %<br />
Zanini B et al. Clin Therapeutic 2010; 32(3):12139-2160)<br />
Cours_Fordd_2013_E.Castro <br />
50
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