Vol.16, No.1 (2012) JSCR Newsletter - 日本糖質学会

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ABh¿(C„…kâ»âQBf==[\AI¿1897 7ƒJ Dd’Cbeëb©hrQkfgd’]ìb\ízy/¿(rhABh0“œõî%¬%—ñùhflÈ/õù¿(¿|0“%)CUVTƒCîˆxpœh-OØxPQBóòfiÄWûwBNÕCîˆTMGNÕW>j@h?T=fi.IäkrX@A=BCD[ä˚DcEWF@B%ijDIJGHDr[\AI=hzy/ı´rÎÏ—hı´CóòIDÒÚı´]J@ÕKL@A@BJ]ÜMDh]rÆCf~MGDô%])5rNMIäE]+êgXAI[2]JOTrií]PíCOQk[ä]+êGQ=ßDI=hRc\M^©†=bEÇÉhRí]C|¢EW}ZA@B¿1874 7P22 áƒJnrPQBZ¥¨h.DiÒDx[\A@BJABhg2“flÎÏ—h]ñùhflÈ/õùxZ¥¨h.DhÁkzTr¥“x.fl¥yõ—Töyõ¿ÉNyzœõƒ]¨i%&Ù0“œõî%GàCjâ˜&ÃDÕÖk@A@BJ]r[\î%W?7l&zx%k[äÓ%m˜+©C^IknWŸgô´]Cºóòkoj@gXAIJoògh%&}°WyzxÔ÷Iäp?DIJ[\AIJrC 1 EW£§@A@S^PÎNõ.flYÎrh·ùß¿Îõî%ƒhr@gÉT“J¿Q“ÎõUî%ƒClDóò@BzhV.ßW.î%CXYZDÉÏhœ«UhC§XC§PD[ªC\!+p[1] M. Tako and S. Nakamura. Carbohydr. Res.,155, 200­205(1986).cä]ürh%firïY=^0_=\c [2] ÒbÚ. [\î%®%©%5'9 , 58,ärìD[ä`EhWa˜Dbc@gXB[äÜ0kh 35­45(2011).JSCR Newsletter Vol.16, No.1 (2012) 5

IJKLMNOPQRDSTUVJWÓ´ÿ5„Móò ¯˘˙˚"%&CY;:-D[\hÓ´ÿ5„Móòfl#Ô%óò«õöCq«õö.D[GQBÛÙrXı´rh2011 7 9 Ü 7 !h»CBÃ_stâQA@BJu7 63 vD@BJÛÙı´rh1976 7 4 Ükh´ÿ5ï?¡´w~koâQhrCzh1Çx%Wfgh19937 1 ÜÇ\´ÿ5ï´y%´ÿ5óòÌz6%óòI.h1995 7 5 ÜÇ\fl†6´¨©.h1999 7 3 ÜÇ\fl{.hr@g#ÿïCóò={MâQÓ„ó=|ìâQBä7C 20027 6 ÜkhÓ„óC#ÔóòC—}~]cä#Ô%óò«õöW|ì@h«õö.]cGQA@BJ2008 7 3 ÜklmâQäADC0hW.flœ®A DNA C%Mfi]ÄDCd¡hÅ"ÄC#fiÔCMfiCd”‘Wã^Ç-1,6-ñõ|hÚa’W–ÖIä Ìz6¿OCH1ƒÙñõ|hœõüÚak¢TIäÌz6¿MNN4, MNN6ƒCùͨõŒhABÄC GPI ¥õµöõúù$C´Mfik¢TIäÌz6ÉCÑÖ]°•c¤hÄC#Ô´¨%]#Ô%CdÜkáèâQhNÕCfiÄW[wGQA@BJÜQGCfiÄkà@h19947kr´ÿ5ï)=hAB 2007 7kr®)%&úù)=(TâQgXAIJı´C_úùróòCîk]¤AGìhfâӴ䢘CÈÍ}Ñù.ìthóòC~^ãhr@g˜+î%ïÙÛÙŒ“ÈC?…óò-kàIä¿]åçXxCD@BJL|c†D_}~âQBCrı´Céè@BÿêrxßM˜CÜ]hı´CEÒë]íXìîkÇä]ÜMxîZMòB]PïgXAIJÁk_NïYòB«õö.OÁrhñ0kó7WÜc@hòMGŒ“È2{ÏõŒkcäÜ]x[\A@B=hò†ôÕAD?…óò-ÙghÖù]:§WK£@gEGQBöryDxõúkFògXAIJAB¤˜ck_NïD[ògxhÅ|CYDrDùQBE]X^û˘r[8xd@BÜ]=[\AH˜D@BJcÕhZÖxüÕhņOkr°~xyØõŒWx\x\~¢GQhI¢gkúkΓâ=[\A@BJâGkóòCó7CM0W£ògr§XWaîhØ’§'Wo…@h•§XC0Cß®WENXIä]¤˜ckôÕ]x^©0ükr–ïõ.=ògÕä]XòBÇ^kh]kMÕDóò9[E]X^ı´DXGò@´XA@BJ?…CóòTCfixƒsD[\hghÖùkr¨c„ûWTê33hÆcdØCx]kóòWªÃâHh%&Ù § X à D fiÄ d ì C f ~W A H A @BJAB2{Ï õ Œ D r gh Ö ù Y œ Dc Õ { ù ¨ µ“ h ö Î kx ' 9 W ª 7Ãœh±øPW@ B H 3 3 Ùä » W @ A@BJÄ]@g î % ï C ±&Ò–hÌo%@h%GWÿòB{ù¨µ“höÎxNÕhã[ä?…óòTWONÕgBÜ]xı´CîZc_úù]XêäD@S^JABhóòkàIäı´C¥êcµcX#fl:§WÄ@ghºóòWîâQäî%flô´CóòTCoxNÕhABGk¥}¥MGCx%´xONÕpœoQA@BJı´róòYœDcÕhE¥xµ/z·xîZDhî&DrDß“õµkhòXÃDE=?D[\hABµ/z·Dr[î˜CDÄ3£EMGcAäC=?D@BJªÃC/ïõ+º“ADZMXc=Gxhä°r°MGEjWxœxœâQgE\hæY—jkcGcX]]rø¿C¡D@BJAB¬7&DrµõöùÍhCƒDÈßõ.W_òB\hO&«C—kO}hß=~\»AQB\]h|œCâxE@ßCı´D@BJX3xyzCÄóòh#ÔóòCo…íW:§@c=Gh[oD‚k’@X†ÌC¢sx¬QgXcMòBı´DI=hq7 ¤YkœeoïWâQg»=#3M\hÂÀW@c=GCóò´}]c\A@BJrQDxı´rÃ⁄WÕÕÜ]cÕ»]ŒX÷œGQA@B=hØzr_˚œk#–GQc=GnØC—\k%MQB]CÜ]DIJßS^¤ GlycoXXI MG“ògZgh'9W”‘gE#’XkãMcœQ´]ÎògXB÷ıCÜ]D@BCDh_˚œMGÿCŸ'C_˜⁄WXBYZh¤ÿ‹]c\A@BJAYAYóòëDC_îˆÙ%&C^ãÃD_}~XBYœäxC]ìïgE\A@B=h[A\kxüI›äEËQ]còg@AXA@BJı´_ÆxsF\Cfir[òBM]Î6JSCR Newsletter Vol.16, No.1 (2012)

IJKLXAI=hı´CóòkàI䧃]hfljkxe‡kìß…M^ö·rh_îˆXBYXBÅ|Ù?…óòTk‚|]pœÔ=QgXÕxC]ÎXAIJsÇ\hı´C_„‰WEÂ\u@vwAIJ1Ç Dartmouth College C Tillman Gerngross ¿(MGhÜC8CÛÙrXı´C÷stk˙@ghï«}WXBYZA@BJGerngross ¿(rh#Ô%C†C9[ÒTD[\hÛÙı´]rêÊcëärcXxCChÛÙı´CEjMGÁËW^œGQhÄW›»@B#öõúù$´ÓWÈèkUª@gEGQAIJProf. Yoshifumi Jigami, a pioneer of yeast glycoengineeringTillman Gerngross,Prof. of Bioengineering, Dartmouth College, USAThe Glycoengineering community has lost one of its early pioneers. Almost twenty years ago Prof.Yoshifumi Jigami led an academic­industry consortium that demonstrated that bakers yeast can begenetically engineered to produce intermediates of glycosylation, formerly only seen in mammalian cells.His detailed knowledge of yeast genetics and glycobiology allowed him to show that specific genedeletions and the introduction of enzymes involved in the processing of glycoproteins can generate yeaststrains that make increasingly human glycan structures. His work provided the encouragement andbelieve that one day it may be possible to produce fully human glycoproteins in yeast. My laboratorybenefited greatly from Prof. Jigami’s insight and pioneering work. He opened the door to a world ofglycoengineering that most thought was impossible and I personally will remain eternally grateful forhis willingness to pave the way for future generations of scientist who followed in his footsteps. Theworld has lost a bold and tenacious scientist who’s work was admired all over the world.JSCR Newsletter Vol.16, No.1 (2012) 7

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-.\]^ICS2012_`\]^?‡î%%© &' ()ICS2012 =h2012 7 7 Ü 22 !R26 !khGyõCñÖœÖkgáàâQA@BJICS r 2 7k 18áàâQhY:C ICS2010 r?¡DáàâQBBÃh‡fiDCáàr 2008 7CzhÍü]c\A@BJ!"Dr˜!^YäÇ^cgâ=÷XgXA@B=hñÖœÖr»õ=”Xc=Gxhi@B»RCHXDhj†k¨k_IÜ]=ÅA@BJ"&:DrÉÑFÇC#Ô¢˜CL|cóòT=1000 Ò¿Õ6A\håçX†CóòklQäÜ]=ÅA@BJy:C%&rhGyõDCáàkx¢£GìhICS2010 COL!"CóòT=ØxNÕ!"IäÄ]c\h!"C#Ôô%kàIäÿ\îCƒsâWmÃgfâIäÜ]=ÅA@BJ%&C!kr Whistler Award Wp)âQBPeter H. Seeberger ¿(Cp)ÑÖ=ã£Qh#ÔC°Mfik3XgCH‚kn\âQBÑÖWÖÕÜ]=ÅA@BJo·kMfi@gXBGfl7xpMä#ÔWqOO0DMfi@g@A^]X^ÿ5rhyzC#Ôô%WdÜâHgXÕvDH‚k»cJ“kcäCDr]ÎXA@BJABhrCzkã£QBØC Plenary Lecture Drh4çÒfiı´kÇä˚rc˚M#$CMfihEÇÉ‘°•c¤k3XgCÑÖ=[\A@BJrC—DxÁkh˚rc#ÔW{|k:\vwgXÕrCÿ5rfl8s#@gxtÕ´M\D@BJä!MGrÏÄÑÖÙ›udåhFlash Communicationhghödå=cA\hF&SD}dc$Å‘v=ã£QgXA@BJy:C%&DrhYoung Investigator Session ]XòB?…óòTC›udå=NÕ|œGQgE\h]gx’wcÑÖWÖÕÜ]=ÅA@BJABh–WFßyù—kã£QgXBghödår˜!î·CÒDk›£ògE\hdåO0=›gxcE|DƒX:§=M£âQhO0=x\cX¤D@BJ]Æry:hÇ˙&:DC FlashCommunication Wã^&WwZh3õŒœz—ÖHPG­7 CÄMfiWdå@A@BJ5 †]X^yO0CdåDr[\A@B=hdåzk Stephen G.Withers ¿(] Daniel B. Werz ¿(ÁãMGC)dC–ïõ.WwZh]Cj=ÉÑk;6âQBÜ]k¢@gH‚kz@ÕÎXA@BJ5 !0k{ògã£QB ICS r[ò]X^0kΣQA@B=h†=o|¢£GcX†k¢@g}RcE«WBÕâ˜$ÕÜ]=ÅgH‚kªc!|W_IÜ]=ÅA@BJØzkhy:C ICS2012 !"k¢@ghICS2010 m,#$ô%À-Ç\_~„WXBYZA@BJÜÜkJÕP:XB@AIJICS2012_`\]^Éî%î%ï%óòô &" *+926:Ç˙#$—õg}õA(26th InternationalCarbohydrate Symposium; ICS 2012)rÄ201277Ü22!(!)Å27!(-)C&DhGyõCñÖœÖkEXgáàâQA@BJ!"ÒO973ÒÄ!"Ç46ÇÇÄ›udårflash communicationWÉÃg368óD[\Äghödå=645óD@BJICSÌC!"rICS2010k3ÃXgi:ìD@B=Ä#$¢˜CóòT=ÉÑ—MG6AògÕä—õg}õAD[äÜ]WmÃgáP@A@BJWhistler)Wp)âQBSeebergerı´C_ÑÖDµygõhÈÍŒ/A=rïA\Ä4çÒfiı´C_ÑÖÄrCzCwelcome cocktailDr!"T=#KWJÃ]gxÆ&YòB]zê$ZA@B¿árp?@BÑãkÖ\ôQÄrCBr—0œ¥v^Äá&Åk!"DZcX]X^WÖïg@AXA@BƒJâgÄ»Wÿ\ê@gä!MGCÑÖk!"ĤC«—ÜõDx}dc:§=K£âQgXA@BJÁkõúYòBC=F«—Üõkyounginvestigator Cdå=AQÄ?…óòTkdåIä&WTêÇ^]Iäö·=ÈÕPïGQA@BJ]rflash communicationDóò⁄W¥Z“@ÄÚá!Cghödåk*îA@BJàR¯äJSCR Newsletter Vol.16, No.1 (2012) 9

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-op.Sialoglyco 2012Date: September 9 – 12, 2012Venue: Academia Sinica, TaipeiURL: http://symposium.ibms.sinica.edu.tw/sialoglyco2012/index.htmlOrganaizer: Fu-óòôöõúùûõü†°¢£§•ù£õßùôù¢£®FCCA«2 / FCCAŒ/y–µygõh?…ί/A2012!OP2012 7 9 Ü 20 !¿ÚƒSPTUVíWXY“¿TUVƒÉ«ÒPÉ«ÒÁåP›eÒ (?flî%)h;Ï© (Å&± J-zy“2“©)U§§'Phttp://www.geocities.jp/y_glycosci/

-op.Dñ%CÀv]@gC#Ôª´¨%EÇ˙—õg}õA!OP2012 7 11 Ü 30 !¿-ƒæzÅ12 Ü 1 !¿ºƒ!SP?¡î%4ç:!Y“¿X¡µ"æ 7-3-1h?¡î%"æØhõúhƒG àP?¡î%î%ïñ%øóòô´b\¨%¿Iº àP?¡î%ŒÍx“ COE ÈÍŒ/AD%NMkÀÃÕ‚À—h{Ay|0—ÜõEh!"%5¿,&óò¡fi¬fij´D|xyzÇ˙ºóò¿¡fiE¿p?ƒÑÖp?TPTatsuro Irimura (ÁËÑÖ), Nicolai Bovin, Henrik Clausen, James W Dennis, Tamao Endo,Olivera J Finn, Minoru Fukuda, Hideki Hasegawa, Shohei Hori, Jamey D Marth, Kouji Matsushima, HisashiNarimatsu, Gabriel A Rabinovich, Hideaki Tahara!"%PlmõÑFµy.Ç\jY%WENXXB@AIJU§r¿!—óáp?JURLPhttp://glycomindedbiology.jimdo.com/>MıPƒ113-0033 ?¡¬X¡µ"æÒvqv^ ?¡î%î%ïñ%øóòô´b\¨%¿Ij78,-P? h¥V ¡6TELP03-5841-4871, 4870 FAXP03-5841-4879 e-mail: ibutsu@mol.f.u-tokyo.ac.jp12JSCR Newsletter Vol.16, No.1 (2012)

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& 31 '#.;Q@/}3Tù°¢49:40 A4-03 y⁄"¥‰ó/hˇÚe˝%âíˆì%gíâÇn67ï îR/YZ3ùûù°¢ß®410:05 A4-04 Çï˜XcÄÅá⁄ì¬˙LJÔXøy⁄"ì©fŸ˛"jñ4óó„XAP¢£/òu‡ú3£ôU;5Q"ôdU‡Ïû£;5,ö410:30 a4-05 trimeric Tn @P¥‰óäãÜõËÇÔX—¨“”&Ç%G+>Q£/)3ùT‡ù°ø£ú@ù(4()*MB»X/µûÇØ34Uªºs/H;410:45 a4-06 ¨Ùü•˘"†¥:l°9¢…ST8SiaII/STXéèXü‚SNP-7Ê°ÙGñópolySia-NCAMÇÛˆ£§Ä$/)3ù°6¤ÜQU)3Tù°¢˙£411:00 A4-07 O-GlcNAc 12¡D¬…â©J"[ü~kÔҤ͕ [/M}~ú3£ ÔX°˚;5ß411:25 a4-08 $âhˇŸ⁄¨"¥:®9¢…38ü†12¥‰ó¤ÜÒìì\@B j/©3T‡411:40 A4-09 ´¨°¡Ò¬óÄÅÆ˝h⁄eâÔXUdhˇ®e"Çü†üøìÇØ®MB»X/µûÇØX3Tù•p±øUü†ú£;5Q"ôd411:55 A4-10 38O-GlcNAcäãåçéèXEogtÇeˇd“"Ÿì¤Ü%&ö2¥x/)òµ3ùT‡ùÔXÄÅø£49r20)%y( tx B.v()*OPQR/S34U+6Ê/349:00 B4-01 [6¥ª(ñó12!íe©Ãà"Ÿ⁄o!ÇÙG;57ºQL/3£ùÓ–°6UÈ93£ùiCeMS49:25 b4-02 N-‹ÙO"ÙOü†¡ÍÎTIM-3 Immunoglobulin—g"Çåçø£ÙGæqø¿x/ûù°¢øUü†;UMN349:40 b4-03 Úf¿ˇ"F~¡±À!8æÓ¥‰óÄŬ‹ÙOü†Ç‚§%&òBC./}N3£3£T MN°¢ú£;5T "Ùük¤Üø£ŸídP49:55 B4-04 3ÂÕ˚ô"ekƒ¥ïëó3¬l˜XMPIaseǤÜìÍÉ2>X/z"h⁄d°ú«»410:20 B4-05 NMR ¡–l…o⁄[!íeì@Çîöœ–%&…2$/H; ü†ÍÉ°6410:45 B4-06 ⁄âˇ#"Çø£ÙG¡j ìñóü†¤Ü%GÇ;5ö> À/S3TH4()*}2,/)òµ34UîBÉ./H;411:10 b5-07 Alg14 organizes the formation of Alg7/13/14 complex involved in N-glycosylationinitiationÃÕ!/}3Tù°¢411:25 b4-08 ¿hER " -1,2 mannosidase IÇin vitro¥µó˝"¸dâŒæm»Ç»œîBÉ./H;ùj7;411:40 B4-09 [6–XÇ˝geˇ—g"¥±bñóê—ü†12üô"ekÇÍÉì¤Ü@“ ”/)3Tù°¢˙U)3ù°6¤ÜQU⁄dIJ"Ÿ3£TPˇŸf&ùIGER412:05 b4-10 GalNAc-TéèXWBSCR17á"zghd!âÿ‘¡•’ñó¯=÷G/È>3U?Ù°¢4JSCR Newsletter Vol.16, No.1 (2012) 23

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