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Possibili eziologie del parto pretermine spontaneo - Associazione ...

Possibili eziologie del parto pretermine spontaneo - Associazione ...

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Cervical Remo<strong>del</strong>ing During Pregnancy<br />

Weeks of Gestation<br />

12 16 18 22 26 28 32 36<br />

Cervical softening<br />

Begins in the first trimester<br />

Slow and incremental<br />

process<br />

↑ compliance<br />

= competence<br />

Labor<br />

Ripening Dilatation Repair<br />

Begins weeks or days preceding birth<br />

More accelerated phase<br />

Maximal loss of tissue compliance<br />

and integrity<br />

Word RA, Li XH Preterm Birth Mechanisms, Mediators, Prediction Prevention and Intervention; Informa UK Ltd:2007

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