Novità in tema di diabete tipo 1 - Ospedale Luigi Sacco
Novità in tema di diabete tipo 1 - Ospedale Luigi Sacco
Novità in tema di diabete tipo 1 - Ospedale Luigi Sacco
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Beta cell mass<br />
1986 NEJM “Stages” <strong>in</strong> Development of Type1Diabetes<br />
Genetic<br />
Pre<strong>di</strong>sposition<br />
(?Precipitat<strong>in</strong>g Event)<br />
Overt<br />
immunologic<br />
abnormalities<br />
Normal <strong>in</strong>sul<strong>in</strong><br />
release<br />
Progressive<br />
loss <strong>in</strong>sul<strong>in</strong><br />
release<br />
Glucose<br />
normal<br />
Age (years)<br />
Overt<br />
<strong>di</strong>abetes<br />
C-peptide<br />
present No<br />
C-peptide