SCLEROSI MULTIPLA E MALATTIE AUTOIMMUNI - Comobrain

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Mult Scler. 2008 Jun;14(5):698-700. Jun;14(5):698 700. Frequency of celiac disease is not increased among multiple sclerosis patients. Nicoletti A, Patti F, Lo Fermo S, Sciacca A, Laisa P, Liberto A, Lanzafame S, Contraffatto D, D'Agate C, Russo A, Zappia M. Dipartimento di Neuroscienze, Università di Catania, Via Santa Sofia no. 78, Catania, Italy. We evaluated the presence of IgA and IgG celiac disease-related disease related antibodies in a sample of 217 patients with multiple sclerosis (MS) and in a sample of 200 controls not affected by neurological disorders. None of the 217 patients with MS presented IgG and IgA anti-gliadin, anti gliadin, anti anti-endomysial endomysial antibodies, anti-tissue anti tissue transglutaminase and anti-reticulin, anti reticulin, whereas only one of the selected controls presented specific antibodies; this subject resulted to be effectively affected by celiac disease. Our data did not show an increased frequency of celiac disease among patients with MS. 1: Clin Neurol Neurosurg. 2007 Oct;109(8):651-3. Epub 2007 May 29. Multiple sclerosis and gluten sensitivity. Borhani Haghighi A, Ansari N, Mokhtari M, Geramizadeh B, Lankarani KB. Department of Neurology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran. borhanihaghighi@yahoo.com OBJECTIVE: To compare the frequency of gluten sensitivity in patients with multiple sclerosis (MS) and healthy controls. PATIENTS AND METHODS: The patients were 161 clinically definite MS patients who referred to neurology outpatient clinic of Nemazee Hospital, Shiraz, south of Iran from March 2004 to October
The GAMES (Genetic Analysis in Multiple sclerosis in EuropeanS) Collaborative Group Geni non MHC candidati alla suscettibilità per SM Jagged 1 (JAG1) Gene implicato nella differenziazione dei precursori degli oligodendrociti POU2AF1 Gene implicato nella regolazione dell’espressione delle cellule B SM - Fattori genetici Screening genomico per linkagedisequilibrium Metanalisi di 13,896 individui
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SCLEROSI MULTIPLA E MALATTIE AUTOIM
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MALATTIE AUTOIMMUNI Autoimmunità:
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Malattie autoimmuni autoimmuni Aut
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MALATTIE AUTOIMMUNI Malattie organo
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MALATTIE AUTOIMMUNI FATTORI GENETIC
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MALATTIE AUTOIMMUNI FATTORI ESOGENI
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Le donne hanno una maggiore propens
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SCLEROSI MULTIPLA (SM) E MALATTIE A
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SM - Fattori genetici Associazioni
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SM - Studi sui gemelli condivisione
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SM - Studi sui gemelli condivisione
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La SM è più frequente in alcune a
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“Molecular mimicry” nella SM
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Molecular mimicry
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Agenti infettivi sospettati nella g
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EBV e SM Persistenza di EBV in tess
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MALATTIE AUTOIMMUNI Fattori ambient
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La Sclerosi Multipla è una malatti
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SM e aCL Transitori riscontri di a
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Gli ANA non sembrano avere un ruolo
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Associazione tra SM e altre malatti
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Associazione tra SM e altre malatti
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Danno assonale Danno mielinico
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ecidivante remittente Tipologia di
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RM midollo Lesioni multiple della s
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Sclerosi multipla remittente-recidi
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Recommended Diagnostic Criteria for
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Lesioni periventricolari
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Lesioni sottocorticali
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Lesioni midollari
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Esame del liquor Assen Assenza za
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LES Ampio spettro di manifestazion
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LES Piccole lesioni focali iperinte
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LES SM-like SM like Immagine assial
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LES Neuropsichiatrico RM encefalo L
Page 74 and 75: LES Neuropsichiatrico Vs. SM Spess
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Page 78 and 79: SM SAP Sindrome da ab anti-fosfolip
Page 80 and 81: Red Flags ! SAP vs. SM RM encefalo
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Page 88 and 89: Sarcoidosi Manifestazioni neurologi
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Page 94 and 95: Neurosarcoidosi MR Zajicek et al.,
Page 96 and 97: Neurosarcoidosi vs. SM Pleiocitosi
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Page 100 and 101: Alterazioni RM: 70 70-80 80% dei c
Page 102 and 103: Red Flags ! M. di Behçet MR Presen
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Page 106 and 107: SM: diagnosi differenziale con MAS
Page 108 and 109: MAS vs. SM Malattie autoimmuni sist
Page 110 and 111: SM: diagnosi differenziale con MAS
Page 112 and 113: LES SAP SM: diagnosi differenziale
Page 114 and 115: LES SAP SM: diagnosi differenziale
Page 117 and 118: SYSTEMIC AUTOIMMUNE CONDITIONS Wege
Page 119 and 120: SYSTEMIC AUTOIMMUNE CONDITIONS WG v
Page 123: Diffuse Brain Damage in SLE Many SL
Page 127 and 128: 1 Sangue periferico Mac Citokine pr
Page 129 and 130: 3 BEE Sangue periferico Citokine pr
Page 131 and 132: Associazione tra SM e altre malatti
Page 133 and 134: Rischio di SM lievemente aumentato
Page 135 and 136: La risposta immunitaria di tipo Th1
Page 137 and 138: Il bersaglio della SM: la guaina mi
Page 139 and 140: Diagnostica elettrofisiologica elet
Page 141 and 142: Neuro Neuro-Be BeÇhet het MS Age a
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SCLEROSI MULTIPLA E MALATTIE AUTOIMMUNI - Comobrain

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