Linfomi ed esposizioni ambientali - Associazione Italiana Registri ...

Chiu, 2006
The association of non-Hodgkin lymphoma (NHL) with agricultural pesticides and farming
activities according to t(14;18) status
Farming status
Control
subjects *
t(14;18)-positive NHL
vs control subjects
Case OR (95%
subjects † CI) ‡
Nonfarmers 419 19 2.0 (0.7-
5.5)
Farmers
Never used
pesticides
229 5 1.0
(referent)
Used pesticides 730 37 2.1 (0.8-
5.4)
Animal
insecticides
11 y
more
Less than
11 y or
Crop
insecticides
12 y
more
17 y
more
417 27 2.6 (1.0-
6.9)
104 5 2.0 (0.5-
7.0)
107 9 3.2 (1.0-
10.1)
Missing 206 13 2.8 (1.0-
7.9)
Less than
12 y or
301 22 3.0 (1.1-
8.2)
82 4 2.1 (0.5-
8.1)
87 9 3.8 (1.2-
12.2)
Missing 132 9 3.0 (1.0-
9.3)
Herbicides 352 25 2.9 (1.1-
7.9)
Less than
17 y or
104 7 2.9 (0.9-
9.4)
109 9 3.2 (1.0-
10.1)
Missing 139 9 3.0 (1.0-
9.1)
t(14;18)-negative NHL
vs control subjects
Case OR (95%
subjects § CI) ‡
P for
difference
31 0.7 (0.4-1.3) .09
23 1.0
(referent)
NA
48 0.7 (0.4-1.2) .04
27 0.7 (0.4-1.3) .02
8 0.9 (0.4-2.0) .3
9 0.9 (0.4-2.1) .08
10 0.5 (0.2-1.1) .01
21 0.7 (0.4-1.4) .02
7 0.9 (0.4-2.3) .3
6 0.8 (0.3-2.0) .03
8 0.6 (0.2-1.4) .02
22 0.7 (0.3-1.2) .01
8 0.8 (0.3-2.0) .09
8 0.8 (0.3-1.9) .06
6 0.4 (0.1-1.1) .007
Fungicides 59 2 NR 3 NR NA
Rodentcides 523 28 2.2 (0.8-
5.8)
Fumigants 112 14 5.0 (1.7-
14.5)
39 0.8 (0.5-1.4) .07
9 0.8 (0.3-1.8) .006