Supporting Information

Table S7. Plant genera with high priority for future screening for overall medicinal bioactivity
These genera were included in the hot nodes of at least two of the study regions (Nepal, New Zealand, and the Cape of South Africa).
Achariaceae: Acharia, Ceratiosicyos, Amaranthaceae: Psilotrichum, Anacardiaceae: Anacardium, Buchanania, Cotinus, Dobinea, Heeria, Laurophyllus, Mangifera,
Pistacia, Rhus, Semecarpus, Spondias, Apocynaceae: Asclepias, Aspidoglossum, Gomphocarpus, Telosma, Xysmalobium, Asteraceae: Marasmodes,
Myriactis, Begoniaceae: Begonia, Betulaceae: Alnus, Betula, Carpinus, Corylus, Brassicaceae: Alliaria, Arabidopsis, Arabis, Barbarea, Brassica, Braya, Cadaba,
Capparis, Capsella, Cardamine, Chamira, Christolea, Cleome, Crateva, Descurainia, Desideria, Dilophia, Diplotaxis, Dontostemon, Draba, Erysimum, Eutrema,
Hedinia, Heliophila, Iberis, Lepidium, Lignariella, Maerua, Megacarpaea, Microsisymbrium, Nasturtium, Notothlaspi, Pachycladon, Pegaeophyton, Phaeonychium,
Raphanus, Rorippa, Sisymbrium, Thlaspi, Torularia, Cannabaceae: Cannabis, Humulus, Caricaceae: Carica, Casuarinaceae: Casuarina, Celastraceae:
Bhesa, Cassine, Celastrus, Elaeodendron, Euonymus, Gloveria, Gymnosporia, Lauridia, Lophopetalum, Maurocenia, Maytenus, Mystroxylon, Putterlickia, Reissantia,
Robsonodendron, Stackhousia, Clusiaceae: Garcinia, Hypericum, Mesua, Combretaceae: Anogeissus, Combretum, Quisqualis, Terminalia, Coriariaceae:
Coriaria, Corynocarpaceae: Corynocarpus, Crassulaceae: Adromischus, Cotyledon, Crassula, Kalanchoe, Sedum, Cucurbitaceae: Benincasa, Biswarea, Bryonia,
Citrullus, Coccinia, Cucumis, Cucurbita, Cyclanthera, Diplocyclos, Edgaria, Gomphogyne, Gymnopetalum, Gynostemma, Herpetospermum, Kedrostis, Lagenaria,
Luffa, Momordica, Mukia, Neoalsomitra, Sechium, Sicyos, Solena, Thladiantha, Trichosanthes, Zehneria, Cunoniaceae: Ackama, Cunonia, Platylophus, Weinmannia,
Daphniphyllaceae: Daphniphyllum, Datiscaceae: Datisca, Tetrameles, Dipterocarpaceae: Shorea, Elaeagnaceae: Elaeagnus, Hippophae, Elaeocarpaceae:
Aristotelia, Elaeocarpus, Sloanea, Elatinaceae: Bergia, Elatine, Escalloniaceae: Ixerba, Euphorbiaceae: Acalypha, Adenocline, Alchornea, Aleurites,
Andrachne, Antidesma, Baccaurea, Baliospermum, Bischofia, Breynia, Bridelia, Chrozophora, Cleidion, Clutia, Croton, Dalechampia, Euphorbia, Excoecaria,
Flueggea, Glochidion, Homalanthus, Hyaenanche, Jatropha, Lachnostylis, Leidesia, Macaranga, Mallotus, Mercurialis, Ostodes, Phyllanthus, Poranthera, Putranjiva,
Ricinus, Sapium, Sauropus, Securinega, Seidelia, Tragia, Trewia, Fabaceae: Abrus, Acacia, Acrocarpus, Aeschynomene, Albizia, Alysicarpus, Amphicarpaea,
Amphithalea, Apios, Arachis, Argyrolobium, Aspalathus, Astragalus, Atylosia, Bauhinia, Bolusafra, Butea, Caesalpinia, Cajanus, Calpurnia, Campylotropis,
Canavalia, Caragana, Carmichaelia, Cassia, Chamaecrista, Chesneya, Cicer, Clianthus, Clitoria, Cochlianthus, Codariocalyx, Colutea, Crotalaria, Cyclopia, Cytisus,
Dalbergia, Delonix, Derris, Desmodium, Dipogon, Dolichos, Dumasia, Dunbaria, Entada, Eriosema, Erythrina, Flemingia, Galactia, Geissaspis, Genista, Glycine,
Glycyrrhiza, Gueldenstaedtia, Hedysarum, Hypocalyptus, Indigofera, Kennedia, Lablab, Lathyrus, Lebeckia, Lens, Lespedeza, Lessertia, Leucaena, Liparia,
Lotononis, Lotus, Lupinus, Macrotyloma, Medicago, Melilotus, Melolobium, Millettia, Mimosa, Montigena, Mucuna, Ormosia, Otholobium, Oxytropis, Paracalyx,
Paraserianthes, Parochetus, Phaseolus, Piptanthus, Pisum, Pithecellobium, Podalyria, Polhillia, Pongamia, Pterocarpus, Pueraria, Rafnia, Rhynchosia,
Robinia, Saraca, Schotia, Senna, Sesbania, Shuteria, Smithia, Sophora, Spatholobus, Stirtonanthus, Tadehagi, Tamarindus, Tephrosia, Thermopsis, Trifolium,
Trigonella, Uraria, Vicia, Vigna, Virgilia, Wiborgia, Wisteria, Xiphotheca, Zornia, Fagaceae: Castanopsis, Lithocarpus, Nothofagus, Quercus, Geissolomataceae:
Geissoloma, Geraniaceae: Erodium, Geranium, Monsonia, Pelargonium, Grossulariaceae: Ribes, Haloragaceae: Gonocarpus, Haloragis, Hamamelidaceae: Exbucklandia,
Trichocephalus, Trichocladus, Juglandaceae: Engelhardia, Juglans, Lamiaceae: Ballota, Galeobdolon, Lamium, Leonotis, Leonurus, Marrubium,
Lauraceae: Cryptocarya, Linaceae: Anisadenia, Linum, Reinwardtia, Loranthaceae: Dendrophthoe, Loranthus, Macrosolen, Moquiniella, Peraxilla, Scurrula,
Septulina, Taxillus, Tupeia, Lythraceae: Ammannia, Cuphea, Duabanga, Lagerstroemia, Lawsonia, Lythrum, Punica, Rotala, Trapa, Woodfordia, Malpighiaceae:
Aspidopterys, Hiptage, Malvaceae: Abroma, Abutilon, Adansonia, Alcea, Anisodontea, Bombax, Byttneria, Corchorus, Entelea, Eriolaena, Firmiana, Gossypium,
Grewia, Helicteres, Hermannia, Hibiscus, Hoheria, Kydia, Lavatera, Malva, Malvaviscus, Melochia, Pavonia, Plagianthus, Pterospermum, Sida, Sparrmannia,
Sterculia, Thespesia, Triumfetta, Urena, Melastomataceae: Medinilla, Melastoma, Osbeckia, Meliaceae: Aglaia, Azadirachta, Chukrasia, Cipadessa, Dysoxylum,
Ekebergia, Melia, Munronia, Nymania, Toona, Trichilia, Melianthaceae: Melianthus, Moraceae: Artocarpus, Ficus, Maclura, Morus, Streblus, Moringaceae:
Moringa, Myricaceae: Morella, Callistemon, Eucalyptus, Eugenia, Kunzea, Leptospermum, Lophomyrtus, Metrosideros, Neomyrtus, Psidium, Syzygium, Neuradaceae:
Grielum, Ochnaceae: Ochna, Olacaceae: Erythropalum, Olax, Schoepfia, Oliniaceae: Olinia, Onagraceae: Chamerion, Circaea, Epilobium, Ludwigia,
Oenothera, Opiliaceae: Cansjera, Lepionurus, Oxalidaceae: Biophytum, Oxalis, Paeoniaceae: Paeonia, Parnassiaceae: Parnassia, Passifloraceae: Passiflora,
Penaeaceae: Brachysiphon, Endonema, Glischrocolla, Penaea, Saltera, Sonderothamnus, Stylapterus, Phyllanthaceae: Aporusa, Poaceae: Australopyrum, Podostemaceae:
Hydrobryum, Polygalaceae: Muraltia, Polygala, Securidaca, Resedaceae: Oligomeris, Rhamnaceae: Berchemia, Discaria, Gouania, Helinus, Hovenia,
Noltea, Paliurus, Phylica, Pomaderris, Rhamnella, Rhamnus, Sageretia, Scutia, Ventilago, Ziziphus, Rhizophoraceae: Carallia, Rosaceae: Acaena,
Agrimonia, Alchemilla, Aruncus, Cliffortia, Cotoneaster, Crataegus, Docynia, Eriobotrya, Filipendula, Fragaria, Geum, Malus, Neillia, Photinia, Potentilla,
Prinsepia, Prunus, Pygeum, Pyracantha, Rosa, Rubus, Sanguisorba, Sibbaldia, Sorbaria, Sorbus, Spiraea, Rutaceae: Acmadenia, Adenandra, Aegle, Agathosma,
Calodendrum, Citrus, Clausena, Coleonema, Diosma, Empleuridium, Empleurum, Euchaetis, Euodia, Glycosmis, Macrostylis, Melicope, Micromelum, Murraya,
Ptaeroxylon, Ruta, Skimmia, Toddalia, Zanthoxylum, Salicaceae: Casearia, Dovyalis, Flacourtia, Gynocardia, Homalium, Kiggelaria, Populus, Salix, Scolopia,
Trimeria, Xylosma, Salvadoraceae: Azima, Santalaceae: Arceuthobium, Dufrenoya, Exocarpus, Korthalsella, Mida, Osyris, Pyrularia, Rhoiacarpos, Santalum,
Thesidium, Thesium, Viscum, Sapindaceae: Acer, Aesculus, Alectryon, Allophylus, Atalaya, Cardiospermum, Dodonaea, Erioglossum, Lepisanthes, Litchi, Pappea,
Sapindus, Schleichera, Smelophyllum, Saxifragaceae: Astilbe, Bergenia, Chrysosplenium, Rodgersia, Saxifraga, Tiarella, Simaroubaceae: Brucea, Picrasma,
Stachyuraceae: Stachyurus, Staphyleaceae: Staphylea, Turpinia, Tamaricaceae: Myricaria, Thymelaeaceae: Aquilaria, Daphne, Drapetes, Edgeworthia, Gnidia,
Lachnaea, Passerina, Pimelea, Stellera, Struthiola, Wikstroemia, Tropaeolaceae: Tropaeolum, Ulmaceae: Celtis, Chaetachme, Holoptelea, Trema, Ulmus, Urticaceae:
Boehmeria, Chamabainia, Dendrocnide, Didymodoxa, Droguetia, Elatostema, Forsskaolea, Girardinia, Gonostegia, Laportea, Lecanthus, Parietaria,
Pilea, Poikilospermum, Procris, Urtica, Violaceae: Hybanthus, Melicytus, Viola, Vitaceae: Ampelocissus, Ampelopsis, Cayratia, Cissus, Cyphostemma, Leea,
Parthenocissus, Rhoicissus, Tetrastigma, Vitis, Zygophyllaceae: Augea, Seetzenia, Tribulus, Zygophyllum.
Table S8. Plant genera with high priority for future screening for conditions related to cardiovascular/blood purity problems
These genera were included in the hot nodes of at least two of the study regions (Nepal, New Zealand, and the Cape of South Africa) for this category of
conditions.
Agavaceae: Cordyline, Anacardiaceae: Anacardium, Buchanania, Cotinus, Dobinea, Heeria, Laurophyllus, Mangifera, Pistacia, Rhus, Semecarpus, Spondias,
Asteraceae: Taraxacum, Fabaceae: Carmichaelia, Sophora, Hemerocallidaceae: Phormium, Loranthaceae: Loranthus, Malvaceae: Alcea, Meliaceae: Aglaia,
Azadirachta, Chukrasia, Cipadessa, Dysoxylum, Ekebergia, Melia, Munronia, Nymania, Toona, Trichilia, Myrtaceae: Leptospermum, Rhamnaceae: Pomaderris,
Rosaceae: Acaena, Rutaceae: Acmadenia, Adenandra, Aegle, Agathosma, Calodendrum, Citrus, Clausena, Coleonema, Diosma, Empleurum, Euchaetis, Euodia,
Glycosmis, Macrostylis, Melicope, Micromelum, Murraya, Ptaeroxylon, Ruta, Skimmia, Toddalia, Zanthoxylum, Sapindaceae: Acer, Aesculus, Alectryon, Allophylus,
Atalaya, Cardiospermum, Dodonaea, Erioglossum, Lepisanthes, Litchi, Pappea, Sapindus, Schleichera, Smelophyllum, Simaroubaceae: Brucea, Picrasma,
Violaceae: Melicytus.
Saslis-Lagoudakis et al. www.pnas.org/cgi/content/short/1202242109 8of25