danarti N 7 - nicergolin-fereini
danarti N 7 - nicergolin-fereini
danarti N 7 - nicergolin-fereini
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gamoyenebis instruqcia<br />
preparat <strong>nicergolin</strong>-<strong>fereini</strong>s ®<br />
НИЦЕРГОЛИН-ФЕРЕЙН®<br />
preparatis savaWro saxelwodeba: <strong>nicergolin</strong>-<strong>fereini</strong><br />
saerTaSoriso arapatentirebuli saxelwodeba: <strong>nicergolin</strong>i<br />
wamlis forma: saineqcio xsnaris dasamzadebeli liofilizati<br />
aRweriloba: forovani masa an TerTi an TiTqmis TeTri feris fxvnili.<br />
Semadgenloba: aqtiuri nivTiereba - <strong>nicergolin</strong>i 0.004 g, damxamare nivTierebebi -<br />
Rvinis mJava, rZis Saqari.<br />
farmalokoTerapiuli jgufi: alfa-adrenoblokatorebi. anatomiur-Terapiuliqimiuri<br />
kodi: С04АЕ02.<br />
farmakologiuri Tvisebebi: Wvavis rqis alkaloidis sinTezuri warmoebuli<br />
nikotinis mJavas bromCabacvlebuli narCenebis mierTebiT. ergolinis narCeni axdens<br />
alfa-adrenomablokirebel qmedebas. iwvevs vazodilatacias da aumjobesebs<br />
mikrocirkulacias. nikotinis mJavas narCenis Semcveloba axdens arteriolebis<br />
kunTovani garsis pirdapir miotropul spazmolizur moqmedebas, zrdis maT<br />
gamtarianobas glukozisaTvis (nivelirebs ergolinis rgolis mopirdapire efeqts).<br />
yvelaze naTlas es moqmedeba gamoixateba Tavis tvinis da kidurebis<br />
sisxlZarRvevis mimarT, aumjobesebs Tavis tvinis, filtvebis da Tirkmelebis<br />
sisxlmomaragebas. amcireba centraluri sisxlZarRvebis winaaRmdegobas, zrdis<br />
arteriul sisxlmomaragebas, zrdis Jangbadis da glukozis miwodebas. aumjobesebs<br />
kidurebis sisxlmomaragebas, gansakuTrebiT funqciuri arteriopaTiis Sedegad<br />
sisxlmomaragebis ukmarisobis dros. Terapiul dozebSi ar moqmedebs arteriul<br />
wnevaze (arteriuli hipertenziiT daavadebul pacientebSi), SeiZleba gamoiwvios<br />
wnevis zomieri daweva.<br />
farmakokinetika.<br />
kargad Seiwova kuWnawlavis traqtis mier. bioSexwevadoba Seadgens 60%. sisxlSi<br />
Cmax ganisazRvreba 2-4 saaTSi. eqvemdebareba biotransformacias RviZlSi<br />
araaqtiuri metabolitebis SeqmniT. ZiriTadad, eqskretirdeba ganavliT.<br />
gamoyenebis Cvenebebi<br />
Tavis tvinis sisxlmomaragebis mwvave da qronikuli daRveva (cerebraluri<br />
aTerosklerozi, cerebruli Trombozi da embolia, tranzitoruli cerebruli<br />
iSemia, posttravmatuli encefalopaTia, fsiqo-organuli sindromi); Tavbrusxveva,<br />
Sakiki: sisxlis mimoqcevis periferuli sistemis sisxlZarRvTa aSliloba<br />
(kidurebis organuli da funqciuri, mwvave da qronikuli arteriopaTiebi,<br />
obliteraciuli endarteriiti, reinos daavadeba, diabeturi angiopaTia). rqovanas<br />
distrofiuli daavadebebi, diabeturi retinopaTia, mxedvelobiTi nervis iSemiuri<br />
neiropaTia. damxmare saSualebis saxiT - arteriuli hipertenziis, hipertonuli<br />
krizis (parenteraluri Seyvanisas) dros.<br />
gamoyenebis wesi da dozebi.<br />
Seyvanis wesi, doza da mkurnalobis kursi damokidebulia pacientis hemodinamikis<br />
individualur maCveneblebze.<br />
<strong>nicergolin</strong>i SehyavT kunTSi, venaSi da arteriSi, winaswar TandarTuli 0.9%<br />
natriumis qloriis xsnarSi preparatis gaxsniT.
kunTSi SehyavT 2-4 mg 2 jer dReSe, venaSi - wveTebad 4-8 mg dozaze 100 ml<br />
natriumis qloridis fiziologiuri xsnariSi (saWiroebis SemTxvevaSi preparatis<br />
Seyvana SeiZleba gameordes ramdenjerme dReSi), arteriaSi SehyavT 4 mg dozaze 10<br />
ml natriumis qloridis fiziologiuri xsnariSi 2 wuTis ganmavlobaSi.<br />
gverdiTi moqmedeba.<br />
dispepsia: Rebineba, gulisreva, diarea, tkivilebi muclis areSi; saxis kanis da<br />
sxeulis zeda nawilis hiperemia, Zilianoba, uZiloba, arteriuli hipotonia, Tavis<br />
tkivili, Tavbrusxveva, stenokardia, ergotizmis simptomebi: kidurebis gaciveba,<br />
kidurebis tkivili da funqciis moSla; qavili, alergiuli reaqciebi.<br />
ukuCvenebebi.<br />
hipermgrZnobeloba; periferuli sisxlZaRvebis gamoxatuli aTerosklerozi; gulis<br />
organuli dazianebebi; daZabulobis stenokardia; miokardis infarqti; arteriuli<br />
hipotonia; orsuloba; laqtaciis periodi.<br />
urTierTqmedeba sxva samkurnalo saSualebebTan.<br />
aZlierebs hipotenziur saSualebaTa, trankvilizatorebis da neiroleptikebis<br />
moqmedebas. simpatomimetikebTan erToblivad gamoyenebisas SeiZleba gamoiwvios<br />
idiosinkrazia. antacidebi da qolestiraminebi aneleben Sewovas.<br />
gansakuTrebuli Cvenebebi.<br />
preparatis parenteraluri Seyvanis Semdeg ortostatikuri efeqtis Tavidan<br />
asacileblad rekomendirebulia horizontalur mdgomareobaSi yofna 10-15 wuTis<br />
ganmavlobaSi.<br />
Tu umoZraod yofnis dros pulsis sixSire wuTSi 50 dartymaze metia, maSin<br />
preparatis miReba SesaZlebelia mxolod samedicino kontrolis gasvlis Semdeg.<br />
gamoSvebis forma.<br />
moqmedi nivTierebis 0.004 g neitraluri feris minis ampulaSi. pvq firiT<br />
dafaruli 5 ampula konturuli ujredovan SefuTvaSi; pvq an sabeWdi lakirebuli<br />
aluminis an SesafuTi masalis firi.<br />
0.9% natriumis qloridis saineqcio izoTeruli xsnari 5 ml neitraluri feris<br />
minis ampulebSi.<br />
kompleqti; erTi konturul ujredovani SefuTva preparatis 5 ampuliT da 0.9%<br />
natriumis qloridis saineqcio izoTeruli xsnaris 5 ampula, gamoyenebis<br />
instruqciiT - moTavsebulia muyaos kolofSi.<br />
Senaxvis pirobebi.<br />
nusxa b. inaxeba sinaTlisagan dacul bavSvebisaTvis miuwvdomel adgilas araumetes<br />
25°C temperaturaze.<br />
Senaxvis vada.<br />
kompleqtis Senaxvis vadaa 3 weli. vargisinobis vadis gasvlis Semdeg gamoyeneba ar<br />
SeiZleba.<br />
afTiaqidan gacemis pirobebi:<br />
farmacevtuli produqtis jgufi II (gamoiyeneba eqimis daniSnulebiT).<br />
mwarmoebeli. daxuruli saaqcio sazogadoeba “brincalov-a”, 113105, ruseTi,<br />
q.moskovi, nagatinskaias quCa 1.
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