Antonio Carlos Martins - IPD-Farma

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A Ca++ activated serine protease (LOPAP) could be responsible for thehaemorrhagic syndrome caused by the caterpillar Lonomia obliqua.C.V. Reis, E.M.A Kelen, S.H.P. Farsky, F.C.V. Portaro, C.A.M.Sampaio, B.L. Fernandes, A.C.M. Camargo, A.M. Chudzinski-Tavassi.Volume 353, (9168), 1942, 1999INPI PI 0200269 January 31, 2002INPI PI 008574-RJ August 24, 2004
Proc. Natl. Acad. Sci. USAVol. 94, pp. 1189–1193, February 1997BiochemistryCloning and sequence analysis of a Bothrops jararacacDNA encoding a precursor of seven bradykininpotentiatingpeptides and a C-type natriuretic peptideNOBUHIRO MURAYAMA*, MIRIAN A. F. HAYASHI†, HIROAKI OHI*, LUIZA A. F. FERREIRA†,VIVIAN V. HERMANN†, HIROMI SAITO*, YOSHIAKI FUJITA*, SHIGESADA HIGUCHI*,BEATRIZ L. FERNANDES‡, TETSUO YAMANE§, AND ANTONIO C. M. DE CAMARGO†*School of Pharmaceutical Sciences, Showa University, 1-5-8 Shinagawa Tokyo 142, Japan; †Biochemical andBiophysical Laboratory and §Biotechnology Center, Instituto Butantan, SP 05503-900, São Paulo, Brazil; and‡Department of Microbiology, Biomedical Sciences Institute, University of São Paulo, 05508-900, São Paulo, BrazilCommunicated by S. M. McCann, Louisiana State University, Baton Rouge, LA, December 17, 1996 (received for reviewSeptember 11, 1996)INPI PI 01/01088-3 March 19, 2001PCT 02/00041 March 18, 2002INPI PI 02/05449-3 December 9, 2002
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