Paulo Lee Ho - IPD-Farma

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Transforming the public health needs inbiotechnological opportunities!Development of technological platforms:- high density growth of cell culture- recombinant proteins in microorganisms- biomolecules purification and characterization- scaling up....Economically viable!
In the case of vaccine, Instituto Butantan strategies are:1. Improvement of the present vaccines (efficacy, potency,yield, adjuvancy – Example: influenza)2. Combination of vaccines3. Development of new projects –- radical innovations- incremental innovations- new uses for known substances- biogenericsRadical innovations:Reverse vaccinology applied to Leptospira
Page 1 and 2: 2 0 Encontro Nacional de Inovação
Page 3 and 4: Brasil, país em desenvolvimento- p
Page 5 and 6: Protozoan InfectionsAmebiasisBalant
Page 7 and 8: "Doenças de Pobres""Doenças que a
Page 9 and 10: O nosso compromisso (missão públi
Page 11 and 12: Science 303: 316, 2004
Page 13 and 14: Centro de Biotecnologia:Prospection
Page 15 and 16: Foccus onRecombinant DNAandmonoclon
Page 17 and 18: Sales potentialNature Reviews Drug
Page 19 and 20: Monoclonal antibodiesNature Reviews
Page 21 and 22: To decide what to do, we need:- Qua
Page 23: Indústria - Lógica do mercadoMerc
Page 27 and 28: ORFs fromL. interrogansCloning, exp
Page 29 and 30: PurificationExpression
Page 31 and 32: Production of porcine pulmonary sur
Page 33 and 34: NormalSíndrome do Desconforto Resp
Page 35 and 36: Creation of a multipurpose GMP pilo
Page 37 and 38: Many thanks for your attention!
Page 40 and 41: São poucos os profissionais com t
Page 42 and 43: Nature 436: 480-483, 2005
Page 44: ERROR: stackunderflowOFFENDING COMM

Paulo Lee Ho - IPD-Farma

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