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Tsutsui et al. Page 20

NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author Manuscript

Fig. 1. GnIH actions within the brain and pituitary

GnIH inhibits gonadotropin synthesis and release by directly acting on the pituitary or by

inhibiting the activity of GnRH neurons. GnIH can also inhibit reproductive behavior by

possibly acting within the brain. Stress induces the expression of GnIH in birds and

mammals. Melatonin induces the expression of GnIH in quail, whereas melatonin inhibits

the expression of GnIH in hamsters.

Gen Comp Endocrinol. Author manuscript; available in PMC 2013 July 01.

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