12.07.2015 Views

HDL - C Factor de risc al aterosclerozei - Medikal.ro

HDL - C Factor de risc al aterosclerozei - Medikal.ro

HDL - C Factor de risc al aterosclerozei - Medikal.ro

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Mo<st<strong>ro</strong>ng>de</st<strong>ro</strong>ng>lul schematic <st<strong>ro</strong>ng>al</st<strong>ro</strong>ng> particulei plasmatice <st<strong>ro</strong>ng>HDL</st<strong>ro</strong>ng>- suprafata este acoperita cu cap polar interactionand cu mediul apos. - Apolipop<strong>ro</strong>teinele sicoleste<strong>ro</strong>lul sunt interc<st<strong>ro</strong>ng>al</st<strong>ro</strong>ng>ate intre capetele polare <st<strong>ro</strong>ng>al</st<strong>ro</strong>ng>e fosfolipi<st<strong>ro</strong>ng>de</st<strong>ro</strong>ng>lor. - Miezul (“core”) cuprin<st<strong>ro</strong>ng>de</st<strong>ro</strong>ng>lipi<st<strong>ro</strong>ng>de</st<strong>ro</strong>ng> neutre, esteri <st<strong>ro</strong>ng>de</st<strong>ro</strong>ng> coleste<strong>ro</strong>l si trigliceri<st<strong>ro</strong>ng>de</st<strong>ro</strong>ng>. - Diverse apolipop<strong>ro</strong>teine sunt prezente peparticulele lipop<strong>ro</strong>teice(ele functioneaza careceptori pentru liganzi, cofactori pentruenzime, p<strong>ro</strong>teine structur<st<strong>ro</strong>ng>al</st<strong>ro</strong>ng>e pentru sinteza lipop<strong>ro</strong>teinelor.

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