HDL - C Factor de risc al aterosclerozei - Medikal.ro

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Rolul lipoproteinelor plasmatice in <strong>de</strong>zvoltarea leziunilor ateroclerotice⇒ <strong>HDL</strong> - lipoproteina antiaterogenica majora - protejeaza <strong>de</strong> ATS prin mecanisme multiple:→ Major: inversarea transportului c.facilitand in<strong>de</strong>partarea c.din celulele spumoase sitransportand c.afaradin peretele vascular si inapoi in ficat.→ In plus: protejeaza LDL <strong>de</strong> oxidare in peretele vascular.
Mecanisme <strong>de</strong> protectieH D LInversareatransportuluicolesteroluluiActivitateaantioxidanta- scoate colesteroluldin peretelearteri<strong>al</strong>e- inhiba cresterea,<strong>de</strong>zvoltareaplacilor noi- crestestabilitateaplacilorpreexistente- inhiba rupereaplacilor- protejeazaLDL <strong>de</strong>oxidare- sca<strong>de</strong> expresiamoleculelor <strong>de</strong>a<strong>de</strong>ziune- mentine integritateaendoteliuluivascular
Page 1 and 2: HDL - CFac
Page 4 and 5: Caracteristica personal</st
Page 6 and 7: CLASIFICAREA FACTORILOR DE RISCTRAD
Page 8 and 9: CLASIFICAREA FACTORILOR DE RISC<str
Page 10 and 11: ↓ HDL (< 35 mg /
Page 12 and 13: Studiul FraminghamRiscul CI prin LD
Page 14 and 15: TrialNoLDL-C(mg/dl
Page 16 and 17: Studiul Helsinki- reducerea CI este
Page 18 and 19: Lipoproteinele si apolipoproteinele
Page 22 and 23: Diagrama venin ilustrand relatia <s
Page 24 and 25: Excesul de coleste
Page 26 and 27: HDL - efectul anti
Page 28 and 29: HDL protejand LDL
Page 30 and 31: Ghidul de tratamen
Page 32 and 33: Statinele cresc HDL</strong
Page 34 and 35: Activarea PPAR αPeroxisome prolife
Page 36: C O N C L U Z I IHDL</stron

HDL - C Factor de risc al aterosclerozei - Medikal.ro

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