Homologi - BEA

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”Biologists look at a sequence and say 'protein X is 43%homologous to protein Y'. Well, it's not. The twosequences can be 43% identical or they can be 43%similar, but they can't be 43% homologous. There is nosuch thing as percent homology. The meaning ofhomologous is 'related by divergent evolution from acommon ancestor'. That's the only thing it means. Youcan't be partially homologous: that would be like beingpartially dead, or partially pregnant. You're eitherhomologous or you're not.”Gregory Petsko (2001), Genome Biology
Ameloot et al., 2001Bishop et al., 2002Kuiper et al., 1996Luke et al., 2005Suzuki et al., 2001
Page 1 and 2: Vad är bioinformatik?• Analysera
Page 3 and 4: Exempel:• Sekvensanalys:- Hitta l
Page 5 and 6: Homologi”Nothing in biology makes
Page 7 and 8: groda padda salamander
Page 9 and 10: grön mambakopparödlaödla
Page 11 and 12: “sugar glider”flygekorredelfin
Page 13 and 14: Genomiska DNA sekvenser hos primate
Page 15 and 16: Proteinsekvenser hos primaterSchimp
Page 17 and 18: • Likheter i biologiska sekvenser
Page 19: Vad är sekvenshomologi• Om två
Page 23 and 24: Sekvenskonservering(sequence conser
Page 25 and 26: Kan två sekvenser vara homologa ut
Page 27 and 28: När likhet inte har med gemensamtu
Page 29 and 30: Marklevande sociala insektertermit(
Page 31 and 32: Hur uppstår homologa sekvenser?•
Page 33 and 34: • Homologa sekvenser som separera
Page 35 and 36: Ortologer vs. paralogerPanthera leo
Page 37 and 38: Paraloga sekvenserPanthera leoPanth
Page 39 and 40: Pseudogener• Det är dock sällan
Page 41 and 42: Antal proteinfamiljer?≈ 60,000 9,

Homologi - BEA

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