12.07.2015 Views

Barbaros Oral

Barbaros Oral

Barbaros Oral

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• Th17’nin ana sitokini IL-17 : akutinflamatuvar sürecin mediatörleri olanTNF-α, IL-1β, IL-6, IL-8 v.b. Sitokinleri;kemokinlerden CXCL1,2 yapımını uyarır.• Kemokinler nötrofil hareketini uyarır ki,nötrofil birikimi Th17 aracılıinflamasyonun ana patolojik bulgusudur.

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